Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42473622 | . | C | A | CCDS12594.1:NM_152296.4:c.2653Gtc>Ttc_NP_689509.1:p.885V>F | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | ILE | A:888 | A:888 | 59.0 | 0.337 | -69.2 | 113.9 | 59.0 | 0.337 | 0.0 | |||||||
| ILE | D:888 | C:888 | 41.0 | 0.234 | -86.1 | 112.0 | NA | NA | NA | ||||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | ILE | A:888 | A:888 | 61.0 | 0.349 | -68.8 | 109.6 | 61.0 | 0.349 | 0.0 | |||||||
| ILE | D:888 | C:888 | 43.0 | 0.246 | -87.5 | 118.2 | NA | NA | NA | ||||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | ILE | A:893 | A:893 | 48.0 | 0.274 | -94.6 | 105.8 | 38.0 | 0.217 | 0.057 |
B:G3MWR4:0.057 |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | ILE | A:893 | A:888 | 59.0 | 0.337 | -97.2 | 105.1 | 35.0 | 0.2 | 0.137 |
B:P05027:0.137 |
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| ILE | D:893 | C:888 | 57.0 | 0.326 | -97.1 | 104.6 | NA | NA | NA | ||||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | ILE | A:893 | A:888 | 45.0 | 0.257 | -92.8 | 104.8 | 37.0 | 0.211 | 0.046 |
B:P05027:0.046 |
||||||
| ILE | D:893 | C:888 | 43.0 | 0.246 | -93.1 | 104.8 | NA | NA | NA | ||||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | ILE | A:893 | A:888 | 41.0 | 0.234 | -91.2 | 103.1 | 35.0 | 0.2 | 0.034 |
B:P05027:0.034 |
||||||
| ILE | D:893 | C:888 | 43.0 | 0.246 | -91.7 | 102.6 | NA | NA | NA | ||||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | ILE | A:893 | A:888 | 46.0 | 0.263 | -93.1 | 105.2 | 38.0 | 0.217 | 0.046 |
B:P05027:0.046 |
DGX |
9.222 |
CD1 |
O3Z |
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| ILE | D:893 | C:888 | 43.0 | 0.246 | -93.1 | 105.2 | NA | NA | NA | ||||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | ILE | A:893 | A:888 | 51.0 | 0.291 | -79.9 | 87.7 | 40.0 | 0.229 | 0.062 |
B:P05027:0.063 |
||||||
| ILE | D:893 | C:888 | 45.0 | 0.257 | -79.3 | 88.2 | NA | NA | NA | ||||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 49.0 | 0.28 | -85.3 | 95.0 | 38.0 | 0.217 | 0.063 |
B:P05027:0.063 |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 50.0 | 0.286 | -84.6 | 88.6 | 38.0 | 0.217 | 0.069 |
B:P05027:0.069 |
H0C |
9.568 |
N |
C40 |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 48.0 | 0.274 | -77.6 | 91.4 | 35.0 | 0.2 | 0.074 |
B:P05027:0.074 |
H0C |
9.088 |
N |
C40 |
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| ILE | C:888 | C:888 | 44.0 | 0.251 | -77.0 | 90.8 | NA | NA | NA | ||||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 50.0 | 0.286 | -77.5 | 91.6 | 37.0 | 0.211 | 0.075 |
B:P05027:0.074 |
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| ILE | D:888 | C:888 | 43.0 | 0.246 | -76.4 | 90.3 | NA | NA | NA | ||||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 51.0 | 0.291 | -81.7 | 88.3 | 41.0 | 0.234 | 0.057 |
B:P05027:0.057 |
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| ILE | D:888 | C:888 | 44.0 | 0.251 | -80.3 | 88.8 | NA | NA | NA | ||||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 42.0 | 0.24 | -82.4 | 88.3 | 32.0 | 0.183 | 0.057 |
B:P05027:0.057 |
DGX |
9.269 |
CD1 |
C6Y |
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| ILE | D:888 | C:888 | 44.0 | 0.251 | -80.9 | 88.1 | NA | NA | NA | ||||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 42.0 | 0.24 | -80.9 | 89.1 | 34.0 | 0.194 | 0.046 |
B:P05027:0.046 |
F9R |
8.430 |
CD1 |
C6Y |
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| ILE | D:888 | C:888 | 42.0 | 0.24 | -78.6 | 91.0 | NA | NA | NA | ||||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 51.0 | 0.291 | -77.8 | 92.5 | 37.0 | 0.211 | 0.08 |
B:P05027:0.08 |
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| ILE | D:888 | C:888 | 46.0 | 0.263 | -77.2 | 90.6 | NA | NA | NA | ||||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 50.0 | 0.286 | -82.7 | 85.6 | 39.0 | 0.223 | 0.063 |
B:P05027:0.063 |
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| ILE | D:888 | C:888 | 45.0 | 0.257 | -81.6 | 86.4 | NA | NA | NA | ||||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:888 | A:888 | 48.0 | 0.274 | -79.5 | 91.8 | 37.0 | 0.211 | 0.063 |
B:P05027:0.063 |
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| ILE | D:888 | C:888 | 44.0 | 0.251 | -77.8 | 91.3 | NA | NA | NA | ||||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | ILE | A:870 | A:888 | 138.0 | 0.789 | -142.7 | 175.6 | 138.0 | 0.789 | 0.0 | |||||||
| ILE | D:870 | C:888 | 117.0 | 0.669 | -135.2 | 170.1 | NA | NA | NA | ||||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | ILE | A:870 | A:888 | 37.0 | 0.211 | -68.5 | 69.0 | 35.0 | 0.2 | 0.011 |
B:P05027:0.011 |
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| ILE | D:870 | C:888 | 39.0 | 0.223 | -68.7 | 68.6 | NA | NA | NA | ||||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ILE | A:864 | A:888 | 40.0 | 0.229 | -45.6 | 107.1 | 38.0 | 0.217 | 0.012 |
B:P05027:0.011 |
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| ILE | D:864 | C:888 | 44.0 | 0.251 | -46.4 | 107.7 | NA | NA | NA | ||||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 24.0 | 0.137 | 0.057 |
B:None:0.057 |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | ILE | A:900 | A:895 | 33.0 | 0.189 | -67.4 | 120.5 | 28.0 | 0.16 | 0.029 |
B:None:0.029 |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 99.0 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 99.0 | 22.0 | 0.126 | 0.068 |
B:C4IX13:0.069 |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 35.0 | 0.2 | -92.9 | 98.9 | 24.0 | 0.137 | 0.063 |
B:C4IX13:0.063 |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.7 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.8 | 22.0 | 0.126 | 0.068 |
B:C4IX13:0.069 |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 22.0 | 0.126 | 0.068 |
B:C4IX13:0.069 |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.9 | 99.0 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 35.0 | 0.2 | -92.8 | 99.0 | 23.0 | 0.131 | 0.069 |
B:C4IX13:0.069 |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 35.0 | 0.2 | -92.8 | 98.9 | 23.0 | 0.131 | 0.069 |
B:C4IX13:0.069 |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 35.0 | 0.2 | -92.7 | 99.0 | 23.0 | 0.131 | 0.069 |
B:C4IX13:0.069 |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.7 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 35.0 | 0.2 | -92.8 | 98.9 | 23.0 | 0.131 | 0.069 |
B:C4IX13:0.069 |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.7 | 98.9 | 22.0 | 0.126 | 0.068 |
B:C4IX13:0.069 |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.7 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -92.8 | 98.9 | 23.0 | 0.131 | 0.063 |
B:C4IX13:0.063 |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:900 | A:895 | 34.0 | 0.194 | -79.5 | 105.0 | 21.0 | 0.12 | 0.074 |
B:C4IX13:0.074 |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | VAL | A:885 | A:885 | 27.0 | 0.174 | -81.9 | 106.7 | ||
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | MET | A:892 | A:892 | 43.0 | 0.232 | -82.7 | 112.9 | ||
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | ILE | A:895 | A:895 | 44.0 | 0.251 | -77.7 | 107.5 | ||