Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42474390 | . | C | A | CCDS12594.1:NM_152296.4:c.2489cGg>cTg_NP_689509.1:p.830R>L | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | LYS | A:833 | A:833 | 129.0 | 0.645 | T | -99.0 | 20.7 | 72.0 | 0.36 | 0.285 |
B:P05027:0.285 |
PC1 PC1 |
6.006 7.172 |
O O |
O14 C14 |
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| LYS | D:833 | C:833 | 165.0 | 0.825 | T | -93.7 | 2.4 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | LYS | A:833 | A:833 | 130.0 | 0.65 | T | -93.0 | 10.2 | 72.0 | 0.36 | 0.29 |
B:P05027:0.29 |
PC1 PC1 |
5.743 7.169 |
O O |
O14 O12 |
|
| LYS | D:833 | C:833 | 161.0 | 0.805 | T | -83.5 | 7.4 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | GLN | A:838 | A:838 | 167.0 | 0.928 | T | -76.5 | -47.4 | 167.0 | 0.928 | 0.0 | ||||||
| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | LYS | A:838 | A:833 | 172.0 | 0.86 | T | -76.7 | -35.4 | 172.0 | 0.86 | 0.0 | ||||||
| LYS | D:838 | C:833 | 175.0 | 0.875 | T | -76.0 | -35.6 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | LYS | A:838 | A:833 | 151.0 | 0.755 | T | -77.0 | -44.0 | 143.0 | 0.715 | 0.04 |
B:P05027:0.04 |
17F 17F |
6.051 9.287 |
O O |
O5 N1 |
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| LYS | D:838 | C:833 | 145.0 | 0.725 | T | -77.2 | -43.5 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | LYS | A:838 | A:833 | 162.0 | 0.81 | T | -82.2 | -41.7 | 162.0 | 0.81 | 0.0 | ||||||
| LYS | D:838 | C:833 | 160.0 | 0.8 | T | -82.4 | -42.3 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | LYS | A:838 | A:833 | 148.0 | 0.74 | T | -78.9 | -42.5 | 148.0 | 0.74 | 0.0 |
17F 17F |
5.203 8.624 |
O O |
O4 N1 |
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| LYS | D:838 | C:833 | 146.0 | 0.73 | T | -78.8 | -42.3 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | LYS | A:838 | A:833 | 143.0 | 0.715 | T | -79.0 | -15.5 | 138.0 | 0.69 | 0.025 |
B:P05027:0.025 |
PCW PCW |
3.802 5.663 |
O CG |
C7 C7 |
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| LYS | D:838 | C:833 | 154.0 | 0.77 | T | -79.0 | -15.8 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 161.0 | 0.805 | T | -96.8 | -6.0 | 161.0 | 0.805 | 0.0 |
PCW PCW |
4.812 9.528 |
O CG |
C8 C6 |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 161.0 | 0.805 | T | -99.1 | -3.7 | 161.0 | 0.805 | 0.0 |
PCW |
6.087 |
O |
C8 |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 147.0 | 0.735 | T | -81.9 | -10.8 | 147.0 | 0.735 | 0.0 |
PCW |
3.851 |
O |
C8 |
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| LYS | C:833 | C:833 | 140.0 | 0.7 | T | -83.9 | -13.4 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 147.0 | 0.735 | T | -81.7 | -11.3 | 147.0 | 0.735 | 0.0 |
PCW |
4.481 |
O |
C7 |
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| LYS | D:833 | C:833 | 140.0 | 0.7 | T | -83.8 | -13.8 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 144.0 | 0.72 | T | -90.5 | -16.2 | 144.0 | 0.72 | 0.0 |
PCW |
4.881 |
O |
C7 |
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| LYS | D:833 | C:833 | 149.0 | 0.745 | T | -91.1 | -17.5 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 150.0 | 0.75 | T | -84.0 | -31.9 | 150.0 | 0.75 | 0.0 |
PCW PCW |
4.407 6.726 |
O CG |
C7 C7 |
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| LYS | D:833 | C:833 | 149.0 | 0.745 | T | -86.3 | -32.9 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 142.0 | 0.71 | T | -77.6 | -11.5 | 142.0 | 0.71 | 0.0 |
PCW PCW |
4.434 5.979 |
O CG |
C7 C7 |
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| LYS | D:833 | C:833 | 149.0 | 0.745 | T | -76.9 | -14.4 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 147.0 | 0.735 | T | -81.9 | -10.8 | 147.0 | 0.735 | 0.0 |
PCW |
3.901 |
O |
C6 |
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| LYS | D:833 | C:833 | 137.0 | 0.685 | T | -84.3 | -13.1 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 144.0 | 0.72 | T | -85.0 | -7.4 | 144.0 | 0.72 | 0.0 |
PCW |
4.691 |
O |
C7 |
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| LYS | D:833 | C:833 | 146.0 | 0.73 | T | -84.6 | -8.9 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | LYS | A:833 | A:833 | 144.0 | 0.72 | T | -84.0 | -11.5 | 144.0 | 0.72 | 0.0 |
PCW PCW |
4.606 5.973 |
O CG |
C7 C7 |
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| LYS | D:833 | C:833 | 140.0 | 0.7 | T | -85.0 | -12.3 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | LYS | A:815 | A:833 | 144.0 | 0.72 | S | -88.2 | -33.0 | 144.0 | 0.72 | 0.0 | ||||||
| LYS | D:815 | C:833 | 160.0 | 0.8 | T | -93.0 | -16.3 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | LYS | A:815 | A:833 | 142.0 | 0.71 | T | -79.8 | -54.9 | 142.0 | 0.71 | 0.0 | ||||||
| LYS | D:815 | C:833 | 148.0 | 0.74 | T | -80.0 | -54.0 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | LYS | A:809 | A:833 | 125.0 | 0.625 | T | -86.2 | -16.0 | 125.0 | 0.625 | 0.0 | ||||||
| LYS | D:809 | C:833 | 126.0 | 0.63 | T | -87.4 | -15.6 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | LYS | A:845 | A:840 | 136.0 | 0.68 | T | -86.0 | -33.0 | 136.0 | 0.68 | 0.0 |
HOH |
3.373 |
CE |
O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | LYS | A:845 | A:840 | 132.0 | 0.66 | T | -79.8 | -39.6 | 132.0 | 0.66 | 0.0 |
HOH |
3.241 |
CG |
O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -85.9 | -33.1 | 135.0 | 0.675 | 0.0 | ||||||
| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.1 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 136.0 | 0.68 | T | -86.0 | -33.0 | 136.0 | 0.68 | 0.0 | ||||||
| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 136.0 | 0.68 | T | -86.1 | -32.9 | 136.0 | 0.68 | 0.0 | ||||||
| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 136.0 | 0.68 | T | -86.0 | -33.0 | 136.0 | 0.68 | 0.0 | ||||||
| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.1 | 135.0 | 0.675 | 0.0 | ||||||
| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -85.9 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 136.0 | 0.68 | T | -86.0 | -33.0 | 136.0 | 0.68 | 0.0 | ||||||
| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -85.9 | -33.1 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.1 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.1 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 136.0 | 0.68 | T | -86.0 | -33.0 | 136.0 | 0.68 | 0.0 | ||||||
| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 135.0 | 0.675 | T | -86.0 | -33.0 | 135.0 | 0.675 | 0.0 | ||||||
| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | LYS | A:845 | A:840 | 138.0 | 0.69 | T | -78.3 | -38.1 | 138.0 | 0.69 | 0.0 |
HOH |
3.341 |
CE |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | ARG | A:830 | A:830 | 187.0 | 0.831 | T | -86.8 | -36.3 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | GLN | A:837 | A:837 | 143.0 | 0.794 | T | -86.6 | -36.4 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | LYS | A:840 | A:840 | 158.0 | 0.79 | T | -84.5 | -35.6 | |