Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42474427 . C A CCDS12594.1:NM_152296.4:c.2452Gaa>Taa_NP_689509.1:p.818E>* Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLU A:821 A:821 13.0 0.068 -71.2 -164.8 13.0 0.068 0.0 HOH
 5.585
 O
 O
GLU D:821 C:821 11.0 0.058 -72.8 -175.5 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLU A:821 A:821 13.0 0.068 -68.7 -157.5 13.0 0.068 0.0 HOH
 5.453
 O
 O
GLU D:821 C:821 12.0 0.063 -79.0 -179.0 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 GLU A:826 A:826 26.0 0.137 S -80.0 -19.7 26.0 0.137 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 GLU A:826 A:821 13.0 0.068 S -51.1 -89.3 13.0 0.068 0.0
GLU D:826 C:821 14.0 0.074 S -49.8 -86.9 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 GLU A:826 A:821 21.0 0.111 S -82.1 -16.2 21.0 0.111 0.0
GLU D:826 C:821 20.0 0.105 S -81.6 -16.3 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLU A:826 A:821 27.0 0.142 S -70.7 -20.6 27.0 0.142 0.0
GLU D:826 C:821 27.0 0.142 S -70.0 -20.7 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLU A:826 A:821 21.0 0.111 S -79.6 -14.4 21.0 0.111 0.0 GLC
 9.983
 O
 O6
GLU D:826 C:821 21.0 0.111 S -79.9 -14.5 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 GLU A:826 A:821 41.0 0.216 S -78.6 -33.3 41.0 0.216 0.0
GLU D:826 C:821 41.0 0.216 S -78.2 -33.3 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 38.0 0.2 S -84.7 -19.5 38.0 0.2 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 37.0 0.195 S -84.4 -18.8 37.0 0.195 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 39.0 0.205 S -85.9 -35.9 39.0 0.205 0.0
GLU C:821 C:821 40.0 0.211 S -86.9 -35.2 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 39.0 0.205 S -85.8 -34.9 39.0 0.205 0.0
GLU D:821 C:821 40.0 0.211 S -87.5 -35.9 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 38.0 0.2 S -84.6 -17.8 38.0 0.2 0.0
GLU D:821 C:821 36.0 0.189 S -85.5 -15.3 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 39.0 0.205 S -77.1 -33.6 39.0 0.205 0.0
GLU D:821 C:821 39.0 0.205 S -76.5 -32.4 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 34.0 0.179 S -69.1 -24.4 34.0 0.179 0.0
GLU D:821 C:821 38.0 0.2 S -69.1 -25.7 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 37.0 0.195 S -86.1 -36.0 37.0 0.195 0.0
GLU D:821 C:821 38.0 0.2 S -87.6 -34.8 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 34.0 0.179 S -79.5 -32.1 34.0 0.179 0.0
GLU D:821 C:821 36.0 0.189 S -81.2 -30.1 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:821 A:821 37.0 0.195 S -85.2 -32.5 37.0 0.195 0.0
GLU D:821 C:821 38.0 0.2 S -86.7 -33.4 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 GLU A:803 A:821 36.0 0.189 -156.0 2.6 36.0 0.189 0.0
GLU D:803 C:821 38.0 0.2 S -144.1 8.7 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 GLU A:803 A:821 32.0 0.168 S -145.5 2.4 32.0 0.168 0.0
GLU D:803 C:821 35.0 0.184 S -146.7 2.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLU A:797 A:821 28.0 0.147 S -74.7 13.7 28.0 0.147 0.0
GLU D:797 C:821 30.0 0.158 S -75.2 13.3 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 GLU A:833 A:828 31.0 0.163 S -84.9 -23.2 31.0 0.163 0.0 HOH
 3.752
 N
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 GLU A:833 A:828 23.0 0.121 S -89.7 -0.5 23.0 0.121 0.0 HOH
 3.434
 N
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.2 31.0 0.163 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.3 31.0 0.163 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.1 31.0 0.163 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.3 31.0 0.163 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -85.0 -23.2 31.0 0.163 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -85.0 -23.1 31.0 0.163 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.1 31.0 0.163 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.2 31.0 0.163 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.2 31.0 0.163 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.2 31.0 0.163 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.3 31.0 0.163 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.1 31.0 0.163 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.3 31.0 0.163 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.2 31.0 0.163 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.3 31.0 0.163 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.2 31.0 0.163 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.2 31.0 0.163 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.8 -23.2 31.0 0.163 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 31.0 0.163 S -84.9 -23.2 31.0 0.163 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:833 A:828 32.0 0.168 S -80.9 -24.4 32.0 0.168 0.0 HOH
 3.479
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 GLU A:818 A:818 36.0 0.189 S -83.5 -19.1
af-p50993-f1 1 P50993 88.81 0.0 GLU A:825 A:825 38.0 0.2 S -82.9 -19.4
af-p05023-f1 1 P05023 88.03 0.0 GLU A:828 A:828 35.0 0.184 S -82.9 -18.1