Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42474454 . C A CCDS12594.1:NM_152296.4:c.2425Gcc>Tcc_NP_689509.1:p.809A>S Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ALA A:812 A:812 1.0 0.009 H -67.5 -49.6 1.0 0.009 0.0 NA
NA
NA
PC1
HOH
 9.182
9.319
7.235
8.089
7.002
 CB
CB
CB
C
CB
 NA
NA
NA
C35
O
ALA D:812 C:812 0.0 0.0 H -61.4 -49.6 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ALA A:812 A:812 0.0 0.0 H -73.6 -40.8 0.0 0.0 0.0 NA
NA
NA
PC1
HOH
 9.020
9.186
6.890
8.256
7.022
 CB
CB
CB
C
CB
 NA
NA
NA
C35
O
ALA D:812 C:812 0.0 0.0 H -64.2 -46.4 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 ALA A:817 A:817 1.0 0.009 H -62.0 -36.3 1.0 0.009 0.0 HOH
 9.304
 CB
 O
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 ALA A:817 A:812 2.0 0.017 H -54.8 -40.5 2.0 0.017 0.0 NA
NA
NA
 8.705
9.787
9.348
 CB
CB
N
 NA
NA
NA
ALA D:817 C:812 2.0 0.017 H -54.3 -40.7 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 ALA A:817 A:812 1.0 0.009 H -62.4 -28.0 1.0 0.009 0.0 HOH
 9.548
 CB
 O
ALA D:817 C:812 1.0 0.009 H -62.7 -28.8 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ALA A:817 A:812 4.0 0.035 H -64.7 -37.1 4.0 0.035 0.0 K
 9.237
 CB
 K
ALA D:817 C:812 3.0 0.026 H -63.7 -37.4 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ALA A:817 A:812 2.0 0.017 H -62.6 -32.7 2.0 0.017 0.0 HOH
 9.414
 CB
 O
ALA D:817 C:812 1.0 0.009 H -62.7 -32.7 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 ALA A:817 A:812 1.0 0.009 H -66.0 -43.4 1.0 0.009 0.0 HOH
 9.158
 CB
 O
ALA D:817 C:812 1.0 0.009 H -65.6 -43.9 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 0.0 0.0 H -65.2 -32.1 0.0 0.0 0.0 PCW
PCW
 7.653
7.484
 C
C
 O31
C32
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 0.0 0.0 H -69.5 -29.2 0.0 0.0 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 1.0 0.009 H -63.3 -34.5 1.0 0.009 0.0 PCW
HOH
 8.317
9.630
 C
CB
 C32
O
ALA C:812 C:812 2.0 0.017 H -62.8 -35.8 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 1.0 0.009 H -62.4 -34.9 1.0 0.009 0.0 RB
PCW
HOH
 9.432
8.085
6.092
 CB
C
CB
 RB
C32
O
ALA D:812 C:812 1.0 0.009 H -62.0 -36.3 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 1.0 0.009 H -66.1 -33.4 1.0 0.009 0.0 PCW
HOH
 6.865
9.462
 C
CB
 O31
O
ALA D:812 C:812 0.0 0.0 H -66.9 -35.3 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 1.0 0.009 H -60.1 -44.2 1.0 0.009 0.0 PCW
HOH
 9.989
9.860
 C
CB
 O31
O
ALA D:812 C:812 0.0 0.0 H -58.6 -42.8 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 0.0 0.0 H -65.4 -39.7 0.0 0.0 0.0 PCW
HOH
 7.350
9.248
 C
CB
 O31
O
ALA D:812 C:812 1.0 0.009 H -64.7 -39.6 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 0.0 0.0 H -62.5 -34.4 0.0 0.0 0.0 PCW
HOH
 9.980
9.855
 N
CB
 O31
O
ALA D:812 C:812 2.0 0.017 H -63.0 -35.7 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 0.0 0.0 H -63.5 -43.3 0.0 0.0 0.0 PCW
HOH
 7.461
9.786
 C
CB
 O31
O
ALA D:812 C:812 1.0 0.009 H -62.5 -44.2 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:812 A:812 1.0 0.009 H -61.8 -39.7 1.0 0.009 0.0 PCW
HOH
 6.597
9.520
 C
CB
 O31
O
ALA D:812 C:812 1.0 0.009 H -62.4 -39.1 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 ALA A:794 A:812 0.0 0.0 H -64.9 -53.0 0.0 0.0 0.0 RB
 9.467
 CB
 RB
ALA D:794 C:812 1.0 0.009 H -63.5 -51.8 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 ALA A:794 A:812 0.0 0.0 H -77.9 -54.2 0.0 0.0 0.0 RB
 9.196
 CB
 RB
ALA D:794 C:812 0.0 0.0 H -76.9 -53.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ALA A:788 A:812 0.0 0.0 H -46.7 -65.3 0.0 0.0 0.0
ALA D:788 C:812 0.0 0.0 H -46.4 -65.7 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 K
HOH
 8.804
5.453
 CB
CB
 K
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 ALA A:824 A:819 1.0 0.009 H -48.3 -56.4 1.0 0.009 0.0 K
HOH
 8.827
6.513
 CB
N
 K
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -42.0 1.0 0.009 0.0 K
TL
HOH
 8.805
8.805
6.667
 CB
CB
CB
 K
TL
O
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 K
TL
HOH
 8.803
8.803
6.666
 CB
CB
CB
 K
TL
O
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -41.9 1.0 0.009 0.0 K
TL
HOH
 8.804
8.804
6.666
 CB
CB
CB
 K
TL
O
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -41.9 1.0 0.009 0.0 K
TL
HOH
 8.804
8.804
6.666
 CB
CB
CB
 K
TL
O
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -42.0 1.0 0.009 0.0 K
TL
HOH
 8.803
8.803
6.665
 CB
CB
CB
 K
TL
O
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.5 -42.0 1.0 0.009 0.0 TL
HOH
 8.803
6.665
 CB
CB
 TL
O
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -41.9 1.0 0.009 0.0 TL
HOH
 8.803
6.665
 CB
CB
 TL
O
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 TL
HOH
 8.804
6.665
 CB
CB
 TL
O
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -41.9 1.0 0.009 0.0 TL
HOH
 8.803
6.665
 CB
CB
 TL
O
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 TL
HOH
 8.804
6.665
 CB
CB
 TL
O
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -42.0 1.0 0.009 0.0 TL
HOH
 8.804
6.666
 CB
CB
 TL
O
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -42.0 1.0 0.009 0.0 K
TL
HOH
 8.805
8.805
6.667
 CB
CB
CB
 K
TL
O
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -42.0 1.0 0.009 0.0 TL
HOH
 8.803
6.665
 CB
CB
 TL
O
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 TL
HOH
 8.804
6.666
 CB
CB
 TL
O
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -41.9 1.0 0.009 0.0 K
RB
HOH
 8.803
8.803
6.665
 CB
CB
CB
 K
RB
O
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.7 -41.9 1.0 0.009 0.0 K
RB
HOH
 8.804
8.804
6.664
 CB
CB
CB
 K
RB
O
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 K
RB
HOH
 8.804
8.804
6.666
 CB
CB
CB
 K
RB
O
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.9 1.0 0.009 0.0 K
RB
HOH
 8.805
8.805
6.665
 CB
CB
CB
 K
RB
O
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -58.6 -41.8 1.0 0.009 0.0 RB
HOH
 8.804
6.664
 CB
CB
 RB
O
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:824 A:819 1.0 0.009 H -59.2 -46.6 1.0 0.009 0.0 K
HOH
 8.753
5.262
 CB
CB
 K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 ALA A:809 A:809 1.0 0.009 H -64.1 -40.2
af-p50993-f1 1 P50993 88.81 0.0 ALA A:816 A:816 0.0 0.0 H -63.1 -44.7
af-p05023-f1 1 P05023 88.03 0.0 ALA A:819 A:819 1.0 0.009 H -64.3 -40.6