Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42474543 | . | G | A | CCDS12594.1:NM_152296.4:c.2415gaC>gaT_NP_689509.1:p.805D>D | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:808 | A:808 | 0.0 | 0.0 | S | -94.2 | 29.5 | 0.0 | 0.0 | 0.0 |
NA NA NA PC1 HOH |
4.795 2.815 3.059 8.313 3.104 |
OD1 OD1 OD2 C CB |
NA NA NA C3B O |
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| ASP | D:808 | C:808 | 3.0 | 0.02 | S | -103.8 | 5.6 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:808 | A:808 | 1.0 | 0.007 | S | -94.3 | 23.8 | 1.0 | 0.007 | 0.0 |
NA NA NA PC1 HOH |
4.836 2.742 3.224 8.528 3.059 |
OD1 OD1 OD2 C OD1 |
NA NA NA C39 O |
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| ASP | D:808 | C:808 | 3.0 | 0.02 | S | -103.0 | 11.7 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | ASP | A:813 | A:813 | 2.0 | 0.013 | T | -53.1 | -15.9 | 2.0 | 0.013 | 0.0 |
MG HOH |
6.829 5.528 |
OD2 OD2 |
MG O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | ASP | A:813 | A:808 | 1.0 | 0.007 | T | -120.6 | -19.5 | 1.0 | 0.007 | 0.0 |
NA NA NA |
4.712 3.598 5.715 |
OD2 OD2 OD1 |
NA NA NA |
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| ASP | D:813 | C:808 | 0.0 | 0.0 | T | -120.1 | -20.4 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | ASP | A:813 | A:808 | 4.0 | 0.027 | T | -53.1 | -17.9 | 4.0 | 0.027 | 0.0 |
MG HOH |
7.111 6.011 |
OD2 OD2 |
MG O |
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| ASP | D:813 | C:808 | 3.0 | 0.02 | T | -53.2 | -18.0 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:813 | A:808 | 4.0 | 0.027 | T | -50.5 | -23.0 | 4.0 | 0.027 | 0.0 |
K K |
5.481 9.276 |
OD2 OD2 |
K K |
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| ASP | D:813 | C:808 | 3.0 | 0.02 | T | -50.5 | -22.7 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:813 | A:808 | 4.0 | 0.027 | T | -53.8 | -16.8 | 4.0 | 0.027 | 0.0 |
MG HOH |
6.984 5.992 |
OD2 OD2 |
MG O |
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| ASP | D:813 | C:808 | 4.0 | 0.027 | T | -53.6 | -16.9 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | ASP | A:813 | A:808 | 5.0 | 0.033 | T | -65.5 | -9.3 | 5.0 | 0.033 | 0.0 |
MG HOH |
6.892 6.149 |
OD2 OD2 |
MG O |
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| ASP | D:813 | C:808 | 4.0 | 0.027 | T | -67.4 | -11.9 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 5.0 | 0.033 | T | -64.3 | 2.1 | 5.0 | 0.033 | 0.0 |
MG PCW PCW |
7.875 9.171 8.454 |
OD2 O O |
MG O31 C32 |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 5.0 | 0.033 | T | -63.7 | 0.7 | 5.0 | 0.033 | 0.0 |
MG HOH |
7.509 6.791 |
OD2 OD2 |
MG O |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 7.0 | 0.047 | T | -52.8 | -16.6 | 7.0 | 0.047 | 0.0 |
MG PCW HOH |
7.179 8.307 6.651 |
OD2 C OD2 |
MG C32 O |
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| ASP | C:808 | C:808 | 7.0 | 0.047 | T | -53.1 | -16.8 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 5.0 | 0.033 | T | -50.7 | -18.2 | 5.0 | 0.033 | 0.0 |
MG RB PCW HOH |
8.803 5.493 9.330 4.659 |
OD2 OD2 O CB |
MG RB C32 O |
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| ASP | D:808 | C:808 | 4.0 | 0.027 | T | -50.4 | -17.1 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 5.0 | 0.033 | T | -62.5 | -2.0 | 5.0 | 0.033 | 0.0 |
MG PCW HOH |
7.347 8.269 6.651 |
OD2 O OD2 |
MG C32 O |
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| ASP | D:808 | C:808 | 3.0 | 0.02 | T | -62.9 | -1.4 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 3.0 | 0.02 | T | -65.2 | 4.9 | 3.0 | 0.02 | 0.0 |
MG HOH |
7.068 6.617 |
OD2 OD2 |
MG O |
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| ASP | D:808 | C:808 | 4.0 | 0.027 | T | -65.9 | 5.1 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 4.0 | 0.027 | T | -59.8 | -8.4 | 4.0 | 0.027 | 0.0 |
MG PCW HOH |
7.361 8.360 6.528 |
OD2 O OD2 |
MG O31 O |
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| ASP | D:808 | C:808 | 6.0 | 0.04 | T | -59.9 | -8.7 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 6.0 | 0.04 | T | -52.7 | -16.5 | 6.0 | 0.04 | 0.0 |
MG HOH |
7.258 6.686 |
OD2 OD2 |
MG O |
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| ASP | D:808 | C:808 | 5.0 | 0.033 | T | -51.3 | -18.3 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 6.0 | 0.04 | T | -59.3 | -4.6 | 6.0 | 0.04 | 0.0 |
MG PCW HOH |
7.919 8.570 7.102 |
OD2 O OD2 |
MG O31 O |
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| ASP | D:808 | C:808 | 7.0 | 0.047 | T | -58.3 | -6.5 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:808 | A:808 | 8.0 | 0.053 | T | -50.5 | -17.1 | 8.0 | 0.053 | 0.0 |
MG PCW HOH |
7.196 7.223 6.628 |
OD2 O OD2 |
MG O31 O |
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| ASP | D:808 | C:808 | 6.0 | 0.04 | T | -50.9 | -15.7 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | ASP | A:790 | A:808 | 0.0 | 0.0 | S | -62.2 | -0.4 | 0.0 | 0.0 | 0.0 |
RB RB |
4.765 8.118 |
OD2 OD2 |
RB RB |
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| ASP | D:790 | C:808 | 3.0 | 0.02 | I | -54.4 | -19.4 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | ASP | A:790 | A:808 | 1.0 | 0.007 | T | -75.9 | -31.8 | 1.0 | 0.007 | 0.0 |
RB RB |
4.327 8.200 |
OD2 OD2 |
RB RB |
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| ASP | D:790 | C:808 | 3.0 | 0.02 | T | -75.8 | -30.0 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ASP | A:784 | A:808 | 4.0 | 0.027 | S | -89.2 | 29.8 | 4.0 | 0.027 | 0.0 | ||||||
| ASP | D:784 | C:808 | 4.0 | 0.027 | S | -89.2 | 30.8 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.1 | 4.0 | 0.027 | 0.0 |
K K HOH |
4.404 7.858 2.668 |
OD2 OD2 OD2 |
K K O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -82.0 | -11.0 | 4.0 | 0.027 | 0.0 |
K K HOH |
4.629 7.901 2.643 |
OD2 OD2 OD1 |
K K O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.1 | 4.0 | 0.027 | 0.0 |
K TL K TL HOH |
4.404 4.404 7.858 7.858 2.668 |
OD2 OD2 OD2 OD2 OD2 |
K TL K TL O |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.4 | -15.1 | 4.0 | 0.027 | 0.0 |
K TL K TL HOH |
4.403 4.403 7.857 7.857 2.668 |
OD2 OD2 OD2 OD2 OD2 |
K TL K TL O |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.1 | 4.0 | 0.027 | 0.0 |
K TL TL HOH |
4.403 4.403 7.858 2.668 |
OD2 OD2 OD2 OD2 |
K TL TL O |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.2 | -15.2 | 4.0 | 0.027 | 0.0 |
K TL TL HOH |
4.403 4.403 7.858 2.668 |
OD2 OD2 OD2 OD2 |
K TL TL O |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.2 | 4.0 | 0.027 | 0.0 |
K TL TL HOH |
4.403 4.403 7.857 2.668 |
OD2 OD2 OD2 OD2 |
K TL TL O |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.3 | -15.1 | 3.0 | 0.02 | 0.0 |
TL TL HOH |
4.403 7.858 2.668 |
OD2 OD2 OD2 |
TL TL O |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.2 | 4.0 | 0.027 | 0.0 |
TL TL HOH |
4.403 7.857 2.668 |
OD2 OD2 OD2 |
TL TL O |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.3 | -15.1 | 3.0 | 0.02 | 0.0 |
TL TL HOH |
4.405 7.858 2.670 |
OD2 OD2 OD2 |
TL TL O |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.4 | -15.0 | 3.0 | 0.02 | 0.0 |
TL TL HOH |
4.404 7.858 2.668 |
OD2 OD2 OD2 |
TL TL O |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.2 | -15.2 | 4.0 | 0.027 | 0.0 |
TL TL HOH |
4.404 7.858 2.668 |
OD2 OD2 OD2 |
TL TL O |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.4 | -15.1 | 3.0 | 0.02 | 0.0 |
TL TL HOH |
4.404 7.858 2.669 |
OD2 OD2 OD2 |
TL TL O |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.3 | -15.1 | 3.0 | 0.02 | 0.0 |
K TL TL HOH |
4.404 4.404 7.858 2.668 |
OD2 OD2 OD2 OD2 |
K TL TL O |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.3 | -15.2 | 3.0 | 0.02 | 0.0 |
TL TL HOH |
4.403 7.857 2.668 |
OD2 OD2 OD2 |
TL TL O |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.4 | -15.0 | 3.0 | 0.02 | 0.0 |
TL TL HOH |
4.404 7.858 2.669 |
OD2 OD2 OD2 |
TL TL O |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.1 | 4.0 | 0.027 | 0.0 |
K RB K RB HOH |
4.405 4.405 7.858 7.858 2.670 |
OD2 OD2 OD2 OD2 OD2 |
K RB K RB O |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -71.4 | -15.0 | 3.0 | 0.02 | 0.0 |
K RB K RB HOH |
4.404 4.404 7.858 7.858 2.669 |
OD2 OD2 OD2 OD2 OD2 |
K RB K RB O |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.1 | 4.0 | 0.027 | 0.0 |
K RB K RB HOH |
4.404 4.404 7.859 7.859 2.669 |
OD2 OD2 OD2 OD2 OD2 |
K RB K RB O |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.3 | -15.2 | 4.0 | 0.027 | 0.0 |
K RB RB HOH |
4.404 4.404 7.858 2.669 |
OD2 OD2 OD2 OD2 |
K RB RB O |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 4.0 | 0.027 | T | -71.2 | -15.2 | 4.0 | 0.027 | 0.0 |
RB RB HOH |
4.404 7.858 2.669 |
OD2 OD2 OD2 |
RB RB O |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:820 | A:815 | 3.0 | 0.02 | T | -74.3 | -19.8 | 3.0 | 0.02 | 0.0 |
K K HOH |
4.417 7.797 2.776 |
OD2 OD2 OD2 |
K K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | ASP | A:805 | A:805 | 2.0 | 0.013 | T | -83.8 | -11.9 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | ASP | A:812 | A:812 | 3.0 | 0.02 | T | -85.6 | -11.9 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | ASP | A:815 | A:815 | 3.0 | 0.02 | T | -81.6 | -12.2 | |