Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42474620 . A C CCDS12594.1:NM_152296.4:c.2338Ttc>Gtc_NP_689509.1:p.780F>V Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 PHE A:783 A:783 4.0 0.019 H -55.1 -28.5 4.0 0.019 0.0 PC1
PC1
CLR
 8.519
8.299
8.456
 O
CE2
C
 C3I
C3F
C27
PHE D:783 C:783 1.0 0.005 H -56.4 -32.5 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 PHE A:783 A:783 4.0 0.019 H -56.4 -28.8 4.0 0.019 0.0 CLR
PC1
PC1
 8.206
8.477
8.213
 C
O
CE2
 C27
C3I
C3F
PHE D:783 C:783 4.0 0.019 H -60.8 -37.1 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 PHE A:788 A:788 58.0 0.276 H -77.8 -16.8 58.0 0.276 0.0 OBN
 3.460
 CG
 C15
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 PHE A:788 A:783 17.0 0.081 H -66.5 -27.5 17.0 0.081 0.0
PHE D:788 C:783 14.0 0.067 H -67.6 -27.5 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 PHE A:788 A:783 52.0 0.248 H -71.7 -16.6 52.0 0.248 0.0 OBN
 3.256
 CG
 C15
PHE D:788 C:783 53.0 0.252 H -71.6 -16.8 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 PHE A:788 A:783 53.0 0.252 H -81.2 -20.0 53.0 0.252 0.0 BUF
 3.264
 CG
 C15
PHE D:788 C:783 51.0 0.243 H -81.8 -19.5 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 PHE A:788 A:783 53.0 0.252 H -71.5 -19.8 53.0 0.252 0.0 DGX
 3.362
 CE1
 C2
PHE D:788 C:783 52.0 0.248 H -71.8 -19.7 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 PHE A:788 A:783 55.0 0.262 H -69.8 -24.5 55.0 0.262 0.0 JEO
CLR
HOH
 3.824
8.631
9.737
 CB
C
CB
 CAC
C26
O
PHE D:788 C:783 54.0 0.257 H -70.0 -28.4 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 74.0 0.352 H -65.5 -37.3 74.0 0.352 0.0 HOH
 9.920
 CB
 O
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 58.0 0.276 H -67.6 -27.8 58.0 0.276 0.0 H0C
CLR
HOH
 3.440
9.729
9.484
 CD1
C
CD2
 C24
C26
O
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 54.0 0.257 H -68.7 -36.2 54.0 0.257 0.0 H0C
HOH
 3.585
9.959
 CD1
CD2
 C24
O
PHE C:783 C:783 55.0 0.262 H -69.2 -36.7 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 51.0 0.243 H -67.7 -37.6 51.0 0.243 0.0 BUF
HOH
 3.515
9.778
 CE1
CD2
 C2
O
PHE D:783 C:783 52.0 0.248 H -68.2 -37.6 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 64.0 0.305 H -66.5 -28.2 64.0 0.305 0.0 CLR
HOH
 8.675
9.679
 C
CB
 C26
O
PHE D:783 C:783 58.0 0.276 H -66.6 -29.7 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 56.0 0.267 H -71.1 -29.4 56.0 0.267 0.0 DGX
CLR
HOH
 3.580
8.510
9.896
 CG
C
CB
 C15
C26
O
PHE D:783 C:783 55.0 0.262 H -72.3 -32.1 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 50.0 0.238 H -69.7 -36.0 50.0 0.238 0.0 F9R
HOH
 3.463
9.776
 CD1
CB
 C15
O
PHE D:783 C:783 49.0 0.233 H -70.8 -36.2 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 47.0 0.224 H -68.7 -36.6 47.0 0.224 0.0 OBN
 3.439
 CG
 C15
PHE D:783 C:783 51.0 0.243 H -68.9 -36.9 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 53.0 0.252 H -70.7 -27.1 53.0 0.252 0.0 E4R
CLR
HOH
 3.460
8.545
9.981
 CD1
C
CB
 C15
C26
O
PHE D:783 C:783 54.0 0.257 H -71.1 -29.5 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 PHE A:783 A:783 51.0 0.243 H -69.2 -38.8 51.0 0.243 0.0 BUF
CLR
HOH
 3.511
8.467
9.976
 CD2
C
CB
 C16
C26
O
PHE D:783 C:783 50.0 0.238 H -69.0 -38.1 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 PHE A:765 A:783 6.0 0.029 H -54.7 -32.5 6.0 0.029 0.0 RB
 9.230
 CE2
 RB
PHE D:765 C:783 9.0 0.043 H -91.2 -31.4 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 PHE A:765 A:783 7.0 0.033 H -50.1 -19.6 7.0 0.033 0.0 RB
CLR
 9.518
9.010
 CE2
C
 RB
C27
PHE D:765 C:783 6.0 0.029 H -51.4 -17.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 PHE A:759 A:783 75.0 0.357 H -105.5 -11.9 75.0 0.357 0.0 OBN
 2.845
 CE1
 C16
PHE D:759 C:783 70.0 0.333 H -105.5 -11.2 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 K
CLR
HOH
 9.486
9.058
5.019
 CE2
C
CE1
 K
C26
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 PHE A:795 A:790 52.0 0.248 H -67.1 -36.7 52.0 0.248 0.0 OBN
CLR
HOH
 3.513
8.511
9.289
 CG
C
CE1
 C16
C26
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 K
TL
CLR
 9.485
9.485
9.059
 CE2
CE2
C
 K
TL
C26
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 K
TL
CLR
 9.486
9.486
9.058
 CE2
CE2
C
 K
TL
C26
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.3 7.0 0.033 0.0 TL
CLR
 9.486
9.058
 CE2
C
 TL
C26
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.3 -35.3 7.0 0.033 0.0 TL
CLR
 9.486
9.057
 CE2
C
 TL
C26
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 TL
CLR
 9.486
9.058
 CE2
C
 TL
C26
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.1 -35.2 7.0 0.033 0.0 TL
CLR
 9.486
9.059
 CE2
C
 TL
C26
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 TL
CLR
 9.486
9.058
 CE2
C
 TL
C26
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 TL
CLR
 9.485
9.060
 CE2
C
 TL
C26
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 TL
CLR
 9.486
9.060
 CE2
C
 TL
C26
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.1 7.0 0.033 0.0 TL
CLR
 9.486
9.058
 CE2
C
 TL
C26
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 TL
CLR
 9.487
9.058
 CE2
C
 TL
C26
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.3 -35.1 7.0 0.033 0.0 TL
CLR
 9.485
9.058
 CE2
C
 TL
C26
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 TL
CLR
 9.486
9.058
 CE2
C
 TL
C26
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.3 7.0 0.033 0.0 TL
CLR
 9.486
9.058
 CE2
C
 TL
C26
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.3 -35.1 7.0 0.033 0.0 K
RB
CLR
 9.487
9.487
9.059
 CE1
CE1
C
 K
RB
C26
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.3 -35.2 7.0 0.033 0.0 K
RB
CLR
 9.486
9.486
9.059
 CE1
CE1
C
 K
RB
C26
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.1 -35.2 7.0 0.033 0.0 K
RB
CLR
 9.485
9.485
9.058
 CE1
CE1
C
 K
RB
C26
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 RB
CLR
 9.486
9.058
 CE1
C
 RB
C26
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -66.2 -35.2 7.0 0.033 0.0 RB
CLR
 9.486
9.059
 CE1
C
 RB
C26
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 PHE A:795 A:790 7.0 0.033 H -67.2 -37.6 7.0 0.033 0.0 K
CLR
HOH
 9.658
8.921
4.855
 CE1
C
CE2
 K
C26
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 PHE A:780 A:780 13.0 0.062 H -66.9 -37.9
af-p50993-f1 1 P50993 88.81 0.0 PHE A:787 A:787 11.0 0.052 H -67.7 -37.9
af-p05023-f1 1 P05023 88.03 0.0 PHE A:790 A:790 15.0 0.071 H -67.8 -39.2