Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42474630 | . | C | A | CCDS12594.1:NM_152296.4:c.2328gaG>gaT_NP_689509.1:p.776E>D | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | GLU | A:779 | A:779 | 1.0 | 0.005 | H | -71.0 | -17.8 | 1.0 | 0.005 | 0.0 |
NA NA NA PC1 CLR HOH |
5.181 2.478 7.342 9.859 9.073 5.422 |
OE1 OE1 OE1 C C OE1 |
NA NA NA C3C C27 O |
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| GLU | D:779 | C:779 | 1.0 | 0.005 | H | -85.7 | -23.7 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | GLU | A:779 | A:779 | 0.0 | 0.0 | H | -69.5 | -22.2 | 0.0 | 0.0 | 0.0 |
NA NA NA CLR PC1 HOH |
5.416 2.451 7.668 8.902 9.854 5.235 |
OE2 OE1 OE1 C C OE1 |
NA NA NA C27 C3C O |
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| GLU | D:779 | C:779 | 1.0 | 0.005 | H | -82.2 | -34.0 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | GLU | A:784 | A:784 | 4.0 | 0.021 | H | -77.5 | -45.4 | 4.0 | 0.021 | 0.0 |
MG OBN HOH |
1.998 5.830 2.700 |
OE2 O OE2 |
MG C21 O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | GLU | A:784 | A:779 | 3.0 | 0.016 | H | -83.6 | -34.5 | 3.0 | 0.016 | 0.0 |
NA NA NA |
6.089 2.417 7.523 |
OE2 OE2 OE1 |
NA NA NA |
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| GLU | D:784 | C:779 | 3.0 | 0.016 | H | -84.5 | -33.6 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | GLU | A:784 | A:779 | 5.0 | 0.026 | H | -79.4 | -47.6 | 5.0 | 0.026 | 0.0 |
MG OBN HOH |
2.039 6.118 2.932 |
OE2 O OE2 |
MG C21 O |
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| GLU | D:784 | C:779 | 4.0 | 0.021 | H | -79.7 | -47.8 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | GLU | A:784 | A:779 | 4.0 | 0.021 | H | -77.6 | -46.5 | 4.0 | 0.021 | 0.0 |
BUF K K |
4.956 3.947 3.992 |
OE2 OE1 OE2 |
O24 K K |
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| GLU | D:784 | C:779 | 3.0 | 0.016 | H | -77.5 | -46.1 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | GLU | A:784 | A:779 | 4.0 | 0.021 | H | -79.7 | -44.9 | 4.0 | 0.021 | 0.0 |
MG DGX HOH |
2.085 6.081 2.721 |
OE2 O OE2 |
MG C21 O |
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| GLU | D:784 | C:779 | 5.0 | 0.026 | H | -79.7 | -45.1 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | GLU | A:784 | A:779 | 8.0 | 0.042 | H | -87.0 | -28.9 | 8.0 | 0.042 | 0.0 |
MG JEO HOH |
2.346 5.220 2.893 |
OE1 O OE1 |
MG OAA O |
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| GLU | D:784 | C:779 | 4.0 | 0.021 | H | -89.2 | -27.9 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 6.0 | 0.032 | H | -93.7 | -47.0 | 6.0 | 0.032 | 0.0 |
MG HOH |
2.285 3.251 |
OE2 OE2 |
MG O |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 4.0 | 0.021 | H | -92.4 | -43.8 | 4.0 | 0.021 | 0.0 |
MG H0C HOH |
2.210 6.092 2.666 |
OE2 O OE2 |
MG C23 O |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 10.0 | 0.053 | H | -85.2 | -28.3 | 10.0 | 0.053 | 0.0 |
MG H0C HOH |
2.213 5.471 2.737 |
OE2 O OE2 |
MG C18 O |
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| GLU | C:779 | C:779 | 7.0 | 0.037 | H | -86.3 | -27.9 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 8.0 | 0.042 | H | -132.4 | -38.1 | 8.0 | 0.042 | 0.0 |
MG RB BUF HOH |
3.783 3.114 5.590 4.712 |
OE2 OE2 O OE2 |
MG RB C16 O |
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| GLU | D:779 | C:779 | 9.0 | 0.047 | H | -131.9 | -37.3 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 6.0 | 0.032 | H | -86.8 | -26.9 | 6.0 | 0.032 | 0.0 |
MG HOH |
2.153 2.426 |
OE2 OE2 |
MG O |
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| GLU | D:779 | C:779 | 8.0 | 0.042 | H | -87.9 | -28.7 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 7.0 | 0.037 | H | -86.9 | -26.7 | 7.0 | 0.037 | 0.0 |
MG DGX HOH |
2.202 5.407 2.828 |
OE2 O OE2 |
MG C16 O |
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| GLU | D:779 | C:779 | 7.0 | 0.037 | H | -87.5 | -26.4 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 7.0 | 0.037 | H | -86.1 | -30.1 | 7.0 | 0.037 | 0.0 |
MG F9R HOH |
2.229 5.466 2.747 |
OE2 O OE2 |
MG C21 O |
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| GLU | D:779 | C:779 | 6.0 | 0.032 | H | -86.3 | -29.6 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 11.0 | 0.058 | H | -85.5 | -28.6 | 11.0 | 0.058 | 0.0 |
MG OBN HOH |
2.235 5.095 2.869 |
OE2 O OE2 |
MG C21 O |
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| GLU | D:779 | C:779 | 7.0 | 0.037 | H | -85.5 | -28.6 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 6.0 | 0.032 | H | -85.9 | -30.8 | 6.0 | 0.032 | 0.0 |
MG E4R HOH |
2.256 5.423 2.791 |
OE2 O OE2 |
MG C22 O |
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| GLU | D:779 | C:779 | 6.0 | 0.032 | H | -87.8 | -29.7 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLU | A:779 | A:779 | 10.0 | 0.053 | H | -86.7 | -27.7 | 10.0 | 0.053 | 0.0 |
MG BUF HOH |
2.236 5.269 2.451 |
OE2 O OE2 |
MG C22 O |
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| GLU | D:779 | C:779 | 7.0 | 0.037 | H | -87.9 | -27.2 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | GLU | A:761 | A:779 | 2.0 | 0.011 | H | -100.8 | -24.7 | 2.0 | 0.011 | 0.0 |
RB RB |
3.521 3.496 |
OE1 OE2 |
RB RB |
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| GLU | D:761 | C:779 | 1.0 | 0.005 | G | -154.2 | 8.0 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | GLU | A:761 | A:779 | 0.0 | 0.0 | H | -144.9 | -35.4 | 0.0 | 0.0 | 0.0 |
RB RB |
3.192 3.188 |
OE2 OE2 |
RB RB |
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| GLU | D:761 | C:779 | 0.0 | 0.0 | H | -145.5 | -35.7 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLU | A:755 | A:779 | 6.0 | 0.032 | H | -100.0 | -28.6 | 6.0 | 0.032 | 0.0 |
OBN |
5.837 |
O |
O23 |
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| GLU | D:755 | C:779 | 6.0 | 0.032 | H | -100.7 | -28.7 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
K K HOH |
3.793 2.924 5.116 |
OE2 OE2 OE1 |
K K O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | GLU | A:791 | A:786 | 4.0 | 0.021 | H | -91.7 | -24.6 | 4.0 | 0.021 | 0.0 |
K K OBN CLR HOH |
3.543 3.079 5.934 9.891 4.688 |
OE2 OE2 O C OE1 |
K K C21 C26 O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
K TL K TL HOH |
3.793 3.793 2.924 2.924 5.115 |
OE2 OE2 OE2 OE2 OE1 |
K TL K TL O |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.6 | 0.0 | 0.0 | 0.0 |
K TL K TL HOH |
3.793 3.793 2.923 2.923 5.115 |
OE2 OE2 OE2 OE2 OE1 |
K TL K TL O |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -97.9 | -25.7 | 0.0 | 0.0 | 0.0 |
K TL TL HOH |
3.792 3.792 2.923 5.114 |
OE2 OE2 OE2 OE1 |
K TL TL O |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.8 | 0.0 | 0.0 | 0.0 |
K TL TL HOH |
3.793 3.793 2.924 5.115 |
OE2 OE2 OE2 OE1 |
K TL TL O |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
K TL TL HOH |
3.793 3.793 2.923 5.116 |
OE2 OE2 OE2 OE1 |
K TL TL O |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.793 2.924 5.116 |
OE2 OE2 OE1 |
TL TL O |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.793 2.923 5.116 |
OE2 OE2 OE1 |
TL TL O |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.1 | -25.6 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.793 2.923 5.117 |
OE2 OE2 OE1 |
TL TL O |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.1 | -25.7 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.794 2.923 5.115 |
OE2 OE2 OE1 |
TL TL O |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.793 2.924 5.116 |
OE2 OE2 OE1 |
TL TL O |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.6 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.793 2.925 5.116 |
OE2 OE2 OE1 |
TL TL O |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
K TL TL HOH |
3.793 3.793 2.923 5.116 |
OE2 OE2 OE2 OE1 |
K TL TL O |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.6 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.794 2.925 5.115 |
OE2 OE2 OE1 |
TL TL O |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
TL TL HOH |
3.793 2.925 5.115 |
OE2 OE2 OE1 |
TL TL O |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
K RB K RB HOH |
3.792 3.792 2.924 2.924 5.117 |
OE2 OE2 OE2 OE2 OE1 |
K RB K RB O |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.7 | 0.0 | 0.0 | 0.0 |
K RB K RB HOH |
3.792 3.792 2.923 2.923 5.118 |
OE2 OE2 OE2 OE2 OE1 |
K RB K RB O |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -97.9 | -25.6 | 0.0 | 0.0 | 0.0 |
K RB K RB HOH |
3.793 3.793 2.924 2.924 5.116 |
OE2 OE2 OE2 OE2 OE1 |
K RB K RB O |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.1 | -25.7 | 0.0 | 0.0 | 0.0 |
K RB RB HOH |
3.793 3.793 2.923 5.117 |
OE2 OE2 OE2 OE1 |
K RB RB O |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.0 | -25.6 | 0.0 | 0.0 | 0.0 |
RB RB HOH |
3.793 2.925 5.117 |
OE2 OE2 OE1 |
RB RB O |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLU | A:791 | A:786 | 0.0 | 0.0 | H | -98.7 | -25.6 | 0.0 | 0.0 | 0.0 |
K K CLR HOH |
3.648 3.038 9.914 5.414 |
OE2 OE2 C OE1 |
K K C26 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | GLU | A:776 | A:776 | 0.0 | 0.0 | H | -90.0 | -38.4 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | GLU | A:783 | A:783 | 0.0 | 0.0 | H | -90.0 | -38.6 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | GLU | A:786 | A:786 | 0.0 | 0.0 | H | -87.2 | -39.6 | |