Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42474635 | . | G | A | CCDS12594.1:NM_152296.4:c.2323Ccg>Tcg_NP_689509.1:p.775P>S | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | PRO | A:778 | A:778 | 2.0 | 0.014 | H | -64.3 | -26.6 | 2.0 | 0.014 | 0.0 |
NA NA PC1 CLR |
7.342 7.616 8.923 7.791 |
CD CG N N |
NA NA C3C C27 |
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| PRO | D:778 | C:778 | 2.0 | 0.014 | H | -67.6 | -4.8 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | PRO | A:778 | A:778 | 1.0 | 0.007 | H | -69.0 | -22.8 | 1.0 | 0.007 | 0.0 |
NA NA CLR PC1 |
7.363 7.997 7.829 8.825 |
CD CG N N |
NA NA C27 C3C |
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| PRO | D:778 | C:778 | 1.0 | 0.007 | H | -68.5 | -10.2 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | PRO | A:783 | A:783 | 0.0 | 0.0 | H | -69.7 | -14.8 | 0.0 | 0.0 | 0.0 |
MG OBN HOH |
7.914 9.248 7.790 |
C O CD |
MG C21 O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | PRO | A:783 | A:778 | 0.0 | 0.0 | H | -70.0 | -9.2 | 0.0 | 0.0 | 0.0 |
NA NA |
7.401 6.329 |
CD CG |
NA NA |
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| PRO | D:783 | C:778 | 0.0 | 0.0 | H | -69.6 | -8.6 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | PRO | A:783 | A:778 | 0.0 | 0.0 | H | -70.9 | -13.9 | 0.0 | 0.0 | 0.0 |
MG OBN HOH |
7.891 9.488 7.560 |
C O CD |
MG C21 O |
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| PRO | D:783 | C:778 | 0.0 | 0.0 | H | -70.8 | -13.8 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | PRO | A:783 | A:778 | 0.0 | 0.0 | H | -69.5 | -13.9 | 0.0 | 0.0 | 0.0 |
BUF K K |
9.201 7.788 9.562 |
C CD C |
C23 K K |
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| PRO | D:783 | C:778 | 0.0 | 0.0 | H | -69.7 | -13.8 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | PRO | A:783 | A:778 | 0.0 | 0.0 | H | -70.8 | -15.2 | 0.0 | 0.0 | 0.0 |
MG DGX HOH |
8.007 9.620 7.788 |
C O CD |
MG C21 O |
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| PRO | D:783 | C:778 | 0.0 | 0.0 | H | -70.8 | -15.2 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | PRO | A:783 | A:778 | 0.0 | 0.0 | H | -72.0 | -8.8 | 0.0 | 0.0 | 0.0 |
MG JEO HOH |
8.103 8.938 7.829 |
C O C |
MG CAC O |
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| PRO | D:783 | C:778 | 0.0 | 0.0 | H | -71.1 | -7.5 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -72.9 | 3.3 | 0.0 | 0.0 | 0.0 |
MG HOH |
8.473 8.882 |
C C |
MG O |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -70.6 | -0.6 | 0.0 | 0.0 | 0.0 |
MG H0C CLR HOH |
8.442 9.878 9.484 7.666 |
C O N CD |
MG C23 C23 O |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -73.2 | -7.9 | 0.0 | 0.0 | 0.0 |
MG H0C HOH |
8.225 9.211 7.729 |
C O C |
MG C18 O |
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| PRO | C:778 | C:778 | 0.0 | 0.0 | H | -72.9 | -7.7 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -79.9 | 36.4 | 0.0 | 0.0 | 0.0 |
MG RB BUF HOH |
8.940 7.448 9.522 9.178 |
C CD O C |
MG RB C23 O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -79.8 | 36.3 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -74.1 | -8.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
8.214 7.569 |
C C |
MG O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -73.2 | -5.9 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -71.3 | -9.2 | 0.0 | 0.0 | 0.0 |
MG DGX HOH |
8.278 9.235 7.903 |
C O C |
MG C16 O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -71.1 | -8.5 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -72.9 | -7.8 | 0.0 | 0.0 | 0.0 |
MG F9R HOH |
8.252 9.319 7.751 |
C O C |
MG C21 O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -73.3 | -7.4 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -72.9 | -8.4 | 0.0 | 0.0 | 0.0 |
MG OBN HOH |
8.304 8.932 7.905 |
C O C |
MG C21 O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -72.4 | -7.7 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -73.6 | -6.6 | 0.0 | 0.0 | 0.0 |
MG E4R HOH |
8.321 9.094 7.996 |
C O C |
MG O23 O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -73.5 | -5.9 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:778 | A:778 | 0.0 | 0.0 | H | -73.4 | -8.8 | 0.0 | 0.0 | 0.0 |
MG BUF HOH |
8.409 8.945 7.839 |
C O C |
MG C23 O |
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| PRO | D:778 | C:778 | 0.0 | 0.0 | H | -74.5 | -8.6 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | PRO | A:760 | A:778 | 0.0 | 0.0 | H | -50.2 | -11.1 | 0.0 | 0.0 | 0.0 |
RB RB |
7.158 8.204 |
CD C |
RB RB |
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| PRO | D:760 | C:778 | 1.0 | 0.007 | G | -62.1 | 26.8 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | PRO | A:760 | A:778 | 0.0 | 0.0 | H | -74.9 | 46.5 | 0.0 | 0.0 | 0.0 |
RB RB |
7.427 8.414 |
CD C |
RB RB |
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| PRO | D:760 | C:778 | 0.0 | 0.0 | H | -73.3 | 46.6 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | PRO | A:754 | A:778 | 0.0 | 0.0 | H | -77.9 | 6.1 | 0.0 | 0.0 | 0.0 |
OBN |
9.740 |
C |
O23 |
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| PRO | D:754 | C:778 | 0.0 | 0.0 | H | -77.5 | 5.8 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.2 | 0.0 | 0.0 | 0.0 |
K K CLR HOH |
7.163 8.402 9.224 8.650 |
CG C N CG |
K K C26 O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -10.6 | 0.0 | 0.0 | 0.0 |
K K OBN CLR HOH |
7.423 8.616 9.766 9.391 8.570 |
CG C O N CG |
K K C16 C26 O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.2 | 0.0 | 0.0 | 0.0 |
K TL K TL CLR HOH |
7.163 7.163 8.402 8.402 9.225 8.649 |
CG CG C C N CG |
K TL K TL C26 O |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.3 | 0.0 | 0.0 | 0.0 |
K TL K TL CLR HOH |
7.163 7.163 8.402 8.402 9.223 8.650 |
CG CG C C N CG |
K TL K TL C26 O |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.3 | 0.0 | 0.0 | 0.0 |
K TL TL CLR HOH |
7.162 7.162 8.402 9.224 8.648 |
CG CG C N CG |
K TL TL C26 O |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.2 | 0.0 | 0.0 | 0.0 |
K TL TL CLR HOH |
7.163 7.163 8.402 9.224 8.651 |
CG CG C N CG |
K TL TL C26 O |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.3 | 0.0 | 0.0 | 0.0 |
K TL TL CLR HOH |
7.163 7.163 8.401 9.224 8.650 |
CG CG C N CG |
K TL TL C26 O |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.2 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.164 8.402 9.224 8.650 |
CG C N CG |
TL TL C26 O |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.2 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.163 8.401 9.224 8.651 |
CG C N CG |
TL TL C26 O |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.2 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.163 8.401 9.224 8.651 |
CG C N CG |
TL TL C26 O |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.2 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.163 8.401 9.224 8.650 |
CG C N CG |
TL TL C26 O |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.3 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.162 8.402 9.223 8.650 |
CG C N CG |
TL TL C26 O |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.2 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.163 8.402 9.224 8.650 |
CG C N CG |
TL TL C26 O |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.3 | 0.0 | 0.0 | 0.0 |
K TL TL CLR HOH |
7.163 7.163 8.402 9.224 8.650 |
CG CG C N CG |
K TL TL C26 O |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.8 | -8.3 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.164 8.403 9.224 8.651 |
CG C N CG |
TL TL C26 O |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.2 | 0.0 | 0.0 | 0.0 |
TL TL CLR HOH |
7.163 8.402 9.225 8.651 |
CG C N CG |
TL TL C26 O |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.2 | 0.0 | 0.0 | 0.0 |
K RB K RB CLR HOH |
7.164 7.164 8.401 8.401 9.223 8.651 |
CG CG C C N CG |
K RB K RB C26 O |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.1 | 0.0 | 0.0 | 0.0 |
K RB K RB CLR HOH |
7.164 7.164 8.401 8.401 9.223 8.652 |
CG CG C C N CG |
K RB K RB C26 O |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -62.9 | -8.3 | 0.0 | 0.0 | 0.0 |
K RB K RB CLR HOH |
7.164 7.164 8.401 8.401 9.224 8.651 |
CG CG C C N CG |
K RB K RB C26 O |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.1 | 0.0 | 0.0 | 0.0 |
K RB RB CLR HOH |
7.163 7.163 8.401 9.224 8.651 |
CG CG C N CG |
K RB RB C26 O |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -63.0 | -8.3 | 0.0 | 0.0 | 0.0 |
RB RB CLR HOH |
7.164 8.402 9.224 8.651 |
CG C N CG |
RB RB C26 O |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:790 | A:785 | 0.0 | 0.0 | H | -68.5 | -5.7 | 0.0 | 0.0 | 0.0 |
K K CLR HOH |
7.289 8.290 9.162 8.719 |
CG C N CG |
K K C26 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | PRO | A:775 | A:775 | 0.0 | 0.0 | H | -62.1 | -14.3 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | PRO | A:782 | A:782 | 0.0 | 0.0 | H | -62.3 | -14.1 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | PRO | A:785 | A:785 | 0.0 | 0.0 | H | -62.6 | -15.1 | |