Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42474646 . G A CCDS12594.1:NM_152296.4:c.2312aCc>aTc_NP_689509.1:p.771T>I Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:774 A:774 1.0 0.007 H -46.8 -67.4 1.0 0.007 0.0 NA
NA
NA
PC1
CLR
HOH
 8.984
5.531
2.491
9.617
9.708
7.861
 N
C
OG1
O
O
N
 NA
NA
NA
C3B
C16
O
THR D:774 C:774 1.0 0.007 H -42.9 -71.9 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:774 A:774 0.0 0.0 H -51.4 -63.4 0.0 0.0 0.0 NA
NA
NA
CLR
PC1
HOH
 9.368
5.554
2.629
9.452
9.538
7.643
 N
C
OG1
O
O
N
 NA
NA
NA
C16
C3B
O
THR D:774 C:774 2.0 0.014 H -61.3 -49.9 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 THR A:779 A:779 2.0 0.014 H -77.3 -25.1 2.0 0.014 0.0 MG
HOH
 7.176
5.923
 C
N
 MG
O
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 THR A:779 A:774 0.0 0.0 H -69.6 -23.7 0.0 0.0 0.0 NA
NA
 6.491
2.366
 C
OG1
 NA
NA
THR D:779 C:774 0.0 0.0 H -69.0 -25.1 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 THR A:779 A:774 3.0 0.021 H -70.0 -27.4 3.0 0.021 0.0 MG
HOH
 7.389
5.904
 C
C
 MG
O
THR D:779 C:774 3.0 0.021 H -69.9 -27.7 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:779 A:774 3.0 0.021 H -71.5 -23.3 3.0 0.021 0.0 K
K
 5.691
9.970
 N
C
 K
K
THR D:779 C:774 3.0 0.021 H -71.4 -23.9 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:779 A:774 3.0 0.021 H -72.0 -28.7 3.0 0.021 0.0 MG
HOH
 7.403
6.022
 C
N
 MG
O
THR D:779 C:774 3.0 0.021 H -71.5 -29.1 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 THR A:779 A:774 3.0 0.021 H -78.2 -40.0 3.0 0.021 0.0 MG
HOH
 7.884
6.195
 C
N
 MG
O
THR D:779 C:774 2.0 0.014 H -76.9 -39.5 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -74.4 -30.9 3.0 0.021 0.0 MG
HOH
 8.115
9.880
 C
C
 MG
O
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -69.8 -33.8 3.0 0.021 0.0 MG
HOH
 8.275
6.290
 C
C
 MG
O
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -80.3 -39.0 3.0 0.021 0.0 MG
HOH
 8.076
6.253
 C
N
 MG
O
THR C:774 C:774 3.0 0.021 H -78.6 -38.4 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -72.7 -34.0 3.0 0.021 0.0 MG
RB
HOH
 9.074
5.961
8.958
 C
C
N
 MG
RB
O
THR D:774 C:774 3.0 0.021 H -74.2 -33.8 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 2.0 0.014 H -74.9 -39.5 2.0 0.014 0.0 MG
HOH
 8.159
6.308
 C
N
 MG
O
THR D:774 C:774 2.0 0.014 H -74.4 -39.7 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -76.0 -39.6 3.0 0.021 0.0 MG
HOH
 8.121
6.380
 C
N
 MG
O
THR D:774 C:774 3.0 0.021 H -75.2 -39.0 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 2.0 0.014 H -77.0 -39.2 2.0 0.014 0.0 MG
HOH
 8.156
6.368
 C
N
 MG
O
THR D:774 C:774 3.0 0.021 H -75.5 -38.5 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -80.8 -39.8 3.0 0.021 0.0 MG
HOH
 8.214
6.501
 C
N
 MG
O
THR D:774 C:774 3.0 0.021 H -80.3 -37.7 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -77.5 -39.7 3.0 0.021 0.0 MG
HOH
 8.324
6.529
 C
N
 MG
O
THR D:774 C:774 2.0 0.014 H -77.3 -40.3 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:774 A:774 3.0 0.021 H -78.5 -34.4 3.0 0.021 0.0 MG
HOH
 8.176
6.492
 C
N
 MG
O
THR D:774 C:774 3.0 0.021 H -78.0 -32.5 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 THR A:756 A:774 1.0 0.007 H -49.7 -38.8 1.0 0.007 0.0 RB
RB
 5.383
8.596
 N
C
 RB
RB
THR D:756 C:774 3.0 0.021 T -98.3 -16.8 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 THR A:756 A:774 3.0 0.021 H -51.4 -43.0 3.0 0.021 0.0 RB
RB
 5.789
9.093
 C
C
 RB
RB
THR D:756 C:774 3.0 0.021 H -51.8 -44.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:750 A:774 2.0 0.014 H -60.8 -38.8 2.0 0.014 0.0
THR D:750 C:774 2.0 0.014 H -60.2 -39.6 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
K
HOH
 5.635
8.596
6.988
 C
C
N
 K
K
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 THR A:786 A:781 3.0 0.021 H -55.5 -46.1 3.0 0.021 0.0 K
K
HOH
 5.703
8.604
7.012
 C
C
N
 K
K
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
TL
K
TL
HOH
 5.635
5.635
8.596
8.596
6.987
 C
C
C
C
N
 K
TL
K
TL
O
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
TL
K
TL
HOH
 5.634
5.634
8.594
8.594
6.988
 C
C
C
C
N
 K
TL
K
TL
O
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
TL
TL
HOH
 5.635
5.635
8.596
6.987
 C
C
C
N
 K
TL
TL
O
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.8 0.0 0.0 0.0 K
TL
TL
HOH
 5.636
5.636
8.596
6.988
 C
C
C
N
 K
TL
TL
O
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.4 -42.0 0.0 0.0 0.0 K
TL
TL
HOH
 5.635
5.635
8.595
6.988
 C
C
C
N
 K
TL
TL
O
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 TL
TL
HOH
 5.636
8.596
6.987
 C
C
N
 TL
TL
O
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.6 -41.9 0.0 0.0 0.0 TL
TL
HOH
 5.636
8.595
6.987
 C
C
N
 TL
TL
O
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.6 -41.8 0.0 0.0 0.0 TL
TL
HOH
 5.635
8.596
6.986
 C
C
N
 TL
TL
O
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.6 -41.8 0.0 0.0 0.0 TL
TL
HOH
 5.635
8.596
6.987
 C
C
N
 TL
TL
O
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.4 -41.9 0.0 0.0 0.0 TL
TL
HOH
 5.635
8.596
6.988
 C
C
N
 TL
TL
O
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 TL
TL
HOH
 5.635
8.596
6.986
 C
C
N
 TL
TL
O
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
TL
TL
HOH
 5.635
5.635
8.595
6.987
 C
C
C
N
 K
TL
TL
O
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.4 -41.9 0.0 0.0 0.0 TL
TL
HOH
 5.636
8.596
6.989
 C
C
N
 TL
TL
O
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 TL
TL
HOH
 5.636
8.596
6.988
 C
C
N
 TL
TL
O
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.8 0.0 0.0 0.0 K
RB
K
RB
HOH
 5.636
5.636
8.595
8.595
6.987
 C
C
C
C
N
 K
RB
K
RB
O
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
RB
K
RB
HOH
 5.636
5.636
8.596
8.596
6.988
 C
C
C
C
N
 K
RB
K
RB
O
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.9 0.0 0.0 0.0 K
RB
K
RB
HOH
 5.636
5.636
8.596
8.596
6.987
 C
C
C
C
N
 K
RB
K
RB
O
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.5 -41.8 0.0 0.0 0.0 K
RB
RB
HOH
 5.635
5.635
8.596
6.987
 C
C
C
N
 K
RB
RB
O
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 0.0 0.0 H -50.4 -41.9 0.0 0.0 0.0 RB
RB
HOH
 5.637
8.597
6.988
 C
C
N
 RB
RB
O
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:786 A:781 1.0 0.007 H -49.0 -47.5 1.0 0.007 0.0 K
K
HOH
 5.665
8.452
6.923
 C
C
N
 K
K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 THR A:771 A:771 2.0 0.014 H -62.2 -38.7
af-p50993-f1 1 P50993 88.81 0.0 THR A:778 A:778 2.0 0.014 H -63.2 -38.3
af-p05023-f1 1 P05023 88.03 0.0 THR A:781 A:781 2.0 0.014 H -71.5 -35.0