Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42474688 . A C CCDS12594.1:NM_152296.4:c.2270cTg>cGg_NP_689509.1:p.757L>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:760 A:760 12.0 0.071 H -72.1 -41.4 12.0 0.071 0.0 HOH
 8.239
 CD2
 O
LEU D:760 C:760 12.0 0.071 H -68.4 -48.5 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:760 A:760 15.0 0.088 H -72.6 -43.8 15.0 0.088 0.0 HOH
 8.182
 CD2
 O
LEU D:760 C:760 13.0 0.076 H -74.9 -39.6 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 LEU A:765 A:765 19.0 0.112 H -79.2 -49.4 19.0 0.112 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 LEU A:765 A:760 10.0 0.059 H -53.2 -48.5 10.0 0.059 0.0
LEU D:765 C:760 10.0 0.059 H -52.8 -48.1 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 LEU A:765 A:760 15.0 0.088 H -76.3 -47.2 15.0 0.088 0.0
LEU D:765 C:760 13.0 0.076 H -75.9 -48.0 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LEU A:765 A:760 27.0 0.159 H -71.3 -57.8 27.0 0.159 0.0
LEU D:765 C:760 27.0 0.159 H -71.5 -57.8 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LEU A:765 A:760 18.0 0.106 H -77.0 -50.6 18.0 0.106 0.0
LEU D:765 C:760 20.0 0.118 H -76.7 -50.7 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 LEU A:765 A:760 22.0 0.129 H -62.0 -53.1 22.0 0.129 0.0
LEU D:765 C:760 21.0 0.124 H -62.2 -53.1 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 6.0 0.035 H -62.6 -46.4 6.0 0.035 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 6.0 0.035 H -61.5 -47.5 6.0 0.035 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 23.0 0.135 H -59.4 -56.5 23.0 0.135 0.0
LEU C:760 C:760 19.0 0.112 H -59.5 -54.0 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 22.0 0.129 H -59.3 -57.0 22.0 0.129 0.0
LEU D:760 C:760 20.0 0.118 H -59.7 -55.5 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 22.0 0.129 H -66.0 -46.2 22.0 0.129 0.0
LEU D:760 C:760 22.0 0.129 H -70.0 -49.6 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 22.0 0.129 H -58.9 -57.0 22.0 0.129 0.0
LEU D:760 C:760 20.0 0.118 H -59.4 -55.3 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 22.0 0.129 H -51.1 -63.5 22.0 0.129 0.0
LEU D:760 C:760 19.0 0.112 H -50.9 -63.8 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 23.0 0.135 H -59.4 -56.1 23.0 0.135 0.0
LEU D:760 C:760 19.0 0.112 H -60.1 -53.4 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 22.0 0.129 H -59.0 -55.4 22.0 0.129 0.0
LEU D:760 C:760 22.0 0.129 H -58.7 -54.8 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:760 A:760 21.0 0.124 H -58.2 -57.9 21.0 0.124 0.0
LEU D:760 C:760 20.0 0.118 H -58.8 -55.5 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 LEU A:742 A:760 17.0 0.1 H -59.5 -59.0 17.0 0.1 0.0
LEU D:742 C:760 11.0 0.065 H -59.3 -59.3 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 LEU A:742 A:760 17.0 0.1 H -87.8 -42.1 17.0 0.1 0.0
LEU D:742 C:760 14.0 0.082 H -87.5 -43.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LEU A:736 A:760 29.0 0.171 H -67.6 -50.0 29.0 0.171 0.0
LEU D:736 C:760 28.0 0.165 H -67.3 -50.2 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0 HOH
 3.356
 CD1
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 LEU A:772 A:767 20.0 0.118 H -51.8 -55.2 20.0 0.118 0.0 HOH
 3.978
 CD2
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.4 -44.3 20.0 0.118 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.4 -44.2 20.0 0.118 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.4 20.0 0.118 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.4 -44.2 20.0 0.118 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.2 -44.3 20.0 0.118 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.2 -44.4 20.0 0.118 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.4 20.0 0.118 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.4 -44.3 20.0 0.118 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.3 20.0 0.118 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.2 -44.3 20.0 0.118 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.4 20.0 0.118 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.4 20.0 0.118 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.3 -44.4 20.0 0.118 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 20.0 0.118 H -60.2 -44.4 20.0 0.118 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:772 A:767 17.0 0.1 H -58.0 -49.1 17.0 0.1 0.0 HOH
 3.445
 CD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 LEU A:757 A:757 17.0 0.1 H -66.1 -47.9
af-p50993-f1 1 P50993 88.81 0.0 LEU A:764 A:764 17.0 0.1 H -66.1 -47.4
af-p05023-f1 1 P05023 88.03 0.0 LEU A:767 A:767 18.0 0.106 H -66.3 -47.5