Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42479820 . C A CCDS12594.1:NM_152296.4:c.2224Gac>Tac_NP_689509.1:p.742D>Y Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ASP A:745 A:745 58.0 0.387 T -91.2 12.6 58.0 0.387 0.0 HOH
 7.621
 O
 O
ASP D:745 C:745 57.0 0.38 T -99.9 -5.2 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ASP A:745 A:745 58.0 0.387 T -94.6 2.2 58.0 0.387 0.0 HOH
 7.170
 O
 O
ASP D:745 C:745 59.0 0.393 T -95.0 -2.5 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 ASP A:750 A:750 66.0 0.44 S -93.6 1.5 66.0 0.44 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 ASP A:750 A:745 59.0 0.393 T -106.7 1.5 59.0 0.393 0.0
ASP D:750 C:745 59.0 0.393 T -106.5 2.3 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 ASP A:750 A:745 63.0 0.42 T -89.2 1.7 63.0 0.42 0.0
ASP D:750 C:745 60.0 0.4 T -89.2 2.4 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ASP A:750 A:745 66.0 0.44 T -80.9 -6.6 66.0 0.44 0.0
ASP D:750 C:745 66.0 0.44 T -81.3 -6.7 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ASP A:750 A:745 61.0 0.407 S -92.9 -3.1 61.0 0.407 0.0
ASP D:750 C:745 65.0 0.433 S -92.0 -0.9 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 ASP A:750 A:745 57.0 0.38 T -89.8 -7.0 57.0 0.38 0.0
ASP D:750 C:745 61.0 0.407 T -90.9 -5.2 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 62.0 0.413 T -90.6 -4.2 62.0 0.413 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 62.0 0.413 T -87.8 -1.9 62.0 0.413 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 55.0 0.367 T -105.3 -3.2 55.0 0.367 0.0
ASP C:745 C:745 58.0 0.387 T -105.1 -1.1 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 56.0 0.373 T -104.8 -3.0 56.0 0.373 0.0
ASP D:745 C:745 60.0 0.4 T -105.2 -1.5 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 64.0 0.427 T -91.3 -6.0 64.0 0.427 0.0
ASP D:745 C:745 62.0 0.413 T -91.1 -3.3 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 63.0 0.42 T -113.9 5.0 63.0 0.42 0.0
ASP D:745 C:745 64.0 0.427 T -112.6 5.2 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 57.0 0.38 T -96.3 -8.2 57.0 0.38 0.0
ASP D:745 C:745 55.0 0.367 T -97.0 -8.8 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 57.0 0.38 T -105.8 -4.0 57.0 0.38 0.0
ASP D:745 C:745 60.0 0.4 T -106.0 -2.5 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 60.0 0.4 T -92.8 -0.7 60.0 0.4 0.0
ASP D:745 C:745 62.0 0.413 T -92.0 -0.3 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ASP A:745 A:745 54.0 0.36 T -105.1 -3.0 54.0 0.36 0.0
ASP D:745 C:745 58.0 0.387 T -105.2 -1.3 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 ASP A:727 A:745 60.0 0.4 S -124.5 4.7 60.0 0.4 0.0
ASP D:727 C:745 60.0 0.4 S -123.9 4.8 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 ASP A:727 A:745 66.0 0.44 T -104.6 15.9 66.0 0.44 0.0
ASP D:727 C:745 67.0 0.447 T -102.8 14.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ASP A:721 A:745 64.0 0.427 S -121.7 -0.5 64.0 0.427 0.0
ASP D:721 C:745 63.0 0.42 S -121.5 -0.5 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0 HOH
 2.755
 OD1
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 ASP A:757 A:752 56.0 0.373 T -102.9 6.3 56.0 0.373 0.0 HOH
 2.707
 OD1
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.2 54.0 0.36 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 55.0 0.367 T -118.0 7.1 55.0 0.367 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 55.0 0.367 T -118.0 7.1 55.0 0.367 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 55.0 0.367 T -118.1 7.1 55.0 0.367 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.1 7.1 54.0 0.36 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 55.0 0.367 T -118.0 7.1 55.0 0.367 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.1 7.1 54.0 0.36 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.1 7.1 54.0 0.36 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.2 54.0 0.36 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.2 54.0 0.36 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.2 54.0 0.36 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.1 7.2 54.0 0.36 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 54.0 0.36 T -118.0 7.1 54.0 0.36 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ASP A:757 A:752 55.0 0.367 T -109.3 8.2 55.0 0.367 0.0 HOH
 2.813
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 ASP A:742 A:742 53.0 0.353 T -105.9 7.1
af-p50993-f1 1 P50993 88.81 0.0 ASP A:749 A:749 55.0 0.367 T -105.7 7.2
af-p05023-f1 1 P05023 88.03 0.0 ASP A:752 A:752 55.0 0.367 T -105.4 7.2