Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42479849 . G A CCDS12594.1:NM_152296.4:c.2195tCc>tTc_NP_689509.1:p.732S>F Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 SER A:735 A:735 0.0 0.0 H -81.3 -39.3 0.0 0.0 0.0 MG
ALF
MG
HOH
 9.912
9.378
7.929
8.422
 OG
OG
OG
OG
 MG
F2
MG
O
SER D:735 C:735 0.0 0.0 H -75.7 -23.7 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 SER A:735 A:735 0.0 0.0 H -71.8 -37.2 0.0 0.0 0.0 ALF
MG
HOH
 9.074
8.257
8.422
 OG
OG
O
 F2
MG
O
SER D:735 C:735 0.0 0.0 H -70.7 -32.4 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 SER A:740 A:740 0.0 0.0 H -69.7 -20.1 0.0 0.0 0.0 MG
MG
HOH
 8.374
9.279
7.655
 OG
O
OG
 MG
MG
O
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 SER A:740 A:735 0.0 0.0 H -74.5 -23.7 0.0 0.0 0.0 ALF
MG
 9.565
8.294
 OG
OG
 F1
MG
SER D:740 C:735 1.0 0.009 H -74.5 -24.6 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 SER A:740 A:735 1.0 0.009 H -76.2 -23.7 1.0 0.009 0.0 MG
MG
 9.180
9.016
 OG
O
 MG
MG
SER D:740 C:735 1.0 0.009 H -75.9 -24.1 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 SER A:740 A:735 2.0 0.017 H -87.7 -10.5 2.0 0.017 0.0 K
MG
 8.871
8.834
 O
OG
 K
MG
SER D:740 C:735 2.0 0.017 H -87.0 -11.4 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 SER A:740 A:735 1.0 0.009 H -67.7 -25.6 1.0 0.009 0.0 MG
MG
 8.922
9.120
 OG
O
 MG
MG
SER D:740 C:735 2.0 0.017 H -67.3 -26.2 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 SER A:740 A:735 0.0 0.0 H -66.8 -19.5 0.0 0.0 0.0 MG
NA
HOH
 7.458
9.287
6.686
 OG
O
OG
 MG
NA
O
SER D:740 C:735 0.0 0.0 H -68.2 -20.2 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -68.9 -16.4 0.0 0.0 0.0 MG
MG
HOH
 7.689
9.244
6.655
 OG
O
OG
 MG
MG
O
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -67.2 -20.3 0.0 0.0 0.0 MG
MG
HOH
 7.672
9.153
6.874
 OG
O
OG
 MG
MG
O
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -69.8 -22.9 0.0 0.0 0.0 MG
NA
HOH
 7.631
9.665
6.538
 OG
O
OG
 MG
NA
O
SER C:735 C:735 0.0 0.0 H -70.8 -22.6 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -69.0 -24.5 0.0 0.0 0.0 MG
NA
HOH
 7.633
9.519
6.551
 OG
O
OG
 MG
NA
O
SER D:735 C:735 1.0 0.009 H -70.7 -23.1 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -66.7 -19.2 0.0 0.0 0.0 MG
NA
HOH
 7.826
9.957
7.142
 OG
O
OG
 MG
NA
O
SER D:735 C:735 0.0 0.0 H -67.2 -20.7 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 1.0 0.009 H -65.4 -31.3 1.0 0.009 0.0 MG
NA
HOH
 7.692
9.311
6.831
 OG
O
OG
 MG
NA
O
SER D:735 C:735 1.0 0.009 H -65.9 -31.7 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -64.1 -27.8 0.0 0.0 0.0 MG
NA
HOH
 7.711
9.514
6.787
 OG
O
OG
 MG
NA
O
SER D:735 C:735 0.0 0.0 H -65.2 -28.3 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -69.5 -22.8 0.0 0.0 0.0 MG
NA
HOH
 7.628
9.866
6.664
 OG
O
OG
 MG
NA
O
SER D:735 C:735 0.0 0.0 H -70.7 -21.8 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -62.5 -30.2 0.0 0.0 0.0 MG
NA
HOH
 7.711
8.973
7.067
 OG
O
OG
 MG
NA
O
SER D:735 C:735 0.0 0.0 H -64.4 -31.5 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:735 A:735 0.0 0.0 H -70.3 -24.3 0.0 0.0 0.0 MG
NA
HOH
 7.607
9.499
6.476
 OG
O
OG
 MG
NA
O
SER D:735 C:735 0.0 0.0 H -71.7 -24.6 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 SER A:717 A:735 0.0 0.0 H -42.0 -44.8 0.0 0.0 0.0 MG
RB
MF4
 8.042
9.742
9.385
 OG
O
OG
 MG
RB
F2
SER D:717 C:735 0.0 0.0 H -41.6 -44.7 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 SER A:717 A:735 0.0 0.0 H -19.9 -53.1 0.0 0.0 0.0 MF4
MG
RB
 9.400
7.948
9.082
 CB
CB
O
 F2
MG
RB
SER D:717 C:735 0.0 0.0 H -19.6 -53.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 SER A:711 A:735 2.0 0.017 H -70.9 -42.7 2.0 0.017 0.0 MG
 8.122
 OG
 MG
SER D:711 C:735 2.0 0.017 H -71.2 -42.9 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 SER A:747 A:742 0.0 0.0 H -56.6 -42.4 0.0 0.0 0.0 MF4
MG
K
HOH
 9.498
8.062
8.953
5.657
 CB
CB
O
N
 F2
MG
K
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 SER A:747 A:742 0.0 0.0 H -53.8 -48.5 0.0 0.0 0.0 MF4
MG
K
HOH
 9.436
7.985
9.707
6.673
 CB
OG
O
CB
 F2
MG
K
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.498
8.063
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
K
TL
 9.498
8.063
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.498
8.063
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.497
8.062
8.953
8.953
 CB
CB
O
O
 F2
MG
K
TL
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
K
TL
 9.497
8.062
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.3 0.0 0.0 0.0 MF4
MG
K
TL
 9.498
8.063
8.953
8.953
 CB
CB
O
O
 F2
MG
K
TL
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.499
8.063
8.954
8.954
 CB
CB
O
O
 F2
MG
K
TL
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.498
8.062
8.953
8.953
 CB
CB
O
O
 F2
MG
K
TL
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
K
TL
 9.497
8.061
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.498
8.062
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.497
8.062
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.7 -42.4 0.0 0.0 0.0 MF4
MG
K
TL
 9.497
8.061
8.953
8.953
 CB
CB
O
O
 F2
MG
K
TL
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
K
TL
 9.499
8.064
8.953
8.953
 CB
CB
O
O
 F2
MG
K
TL
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.3 0.0 0.0 0.0 MF4
MG
K
TL
 9.497
8.062
8.952
8.952
 CB
CB
O
O
 F2
MG
K
TL
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
K
RB
 9.498
8.062
8.952
8.952
 CB
CB
O
O
 F2
MG
K
RB
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
K
RB
 9.498
8.064
8.953
8.953
 CB
CB
O
O
 F2
MG
K
RB
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.6 -42.5 0.0 0.0 0.0 MF4
MG
K
RB
 9.499
8.063
8.952
8.952
 CB
CB
O
O
 F2
MG
K
RB
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.4 0.0 0.0 0.0 MF4
MG
K
RB
 9.499
8.063
8.952
8.952
 CB
CB
O
O
 F2
MG
K
RB
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -56.5 -42.5 0.0 0.0 0.0 MF4
MG
RB
 9.498
8.063
8.953
 CB
CB
O
 F2
MG
RB
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:747 A:742 0.0 0.0 H -57.7 -44.1 0.0 0.0 0.0 MF4
MG
K
HOH
 9.510
7.930
8.906
5.760
 CB
CB
O
N
 F2
MG
K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 SER A:732 A:732 0.0 0.0 H -66.1 -43.2
af-p50993-f1 1 P50993 88.81 0.0 SER A:739 A:739 0.0 0.0 H -61.0 -42.4
af-p05023-f1 1 P05023 88.03 0.0 SER A:742 A:742 0.0 0.0 H -65.8 -43.0