Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42479900 . A C CCDS12594.1:NM_152296.4:c.2144cTg>cGg_NP_689509.1:p.715L>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:718 A:718 0.0 0.0 H -46.2 -34.4 0.0 0.0 0.0 ALF
MG
NA
HOH
 9.962
9.128
5.274
3.742
 CD1
CD1
O
O
 F2
MG
NA
O
LEU D:718 C:718 0.0 0.0 H -47.4 -41.7 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:718 A:718 0.0 0.0 H -67.8 -11.2 0.0 0.0 0.0 ALF
MG
NA
HOH
 9.763
9.257
5.708
3.459
 CD1
CD1
O
O
 F2
MG
NA
O
LEU D:718 C:718 0.0 0.0 H -40.9 -44.2 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 LEU A:723 A:723 0.0 0.0 H -53.9 -29.8 0.0 0.0 0.0 MG
MG
HOH
 8.892
4.638
8.115
 CD1
O
CD1
 MG
MG
O
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 SER A:723 A:718 3.0 0.026 H -78.7 -0.3 3.0 0.026 0.0
SER D:723 C:718 3.0 0.026 H -79.0 -0.0 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 SER A:723 A:718 0.0 0.0 H -58.1 -30.0 0.0 0.0 0.0 MG
 4.316
 O
 MG
SER D:723 C:718 0.0 0.0 H -58.1 -30.7 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 SER A:723 A:718 2.0 0.017 H -70.0 -18.9 2.0 0.017 0.0 K
 3.695
 O
 K
SER D:723 C:718 3.0 0.026 H -71.2 -18.1 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 SER A:723 A:718 1.0 0.009 H -56.7 -32.5 1.0 0.009 0.0 MG
 4.433
 O
 MG
SER D:723 C:718 1.0 0.009 H -56.5 -32.8 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 SER A:723 A:718 0.0 0.0 H -72.8 -34.7 0.0 0.0 0.0 MG
NA
HOH
 9.677
4.486
8.671
 OG
O
OG
 MG
NA
O
SER D:723 C:718 1.0 0.009 H -75.1 -32.9 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -78.3 -18.0 0.0 0.0 0.0 MG
MG
HOH
 9.525
3.851
4.880
 OG
O
O
 MG
MG
O
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -77.4 -14.7 0.0 0.0 0.0 MG
MG
HOH
 9.359
3.862
4.832
 OG
O
O
 MG
MG
O
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -72.6 -30.0 0.0 0.0 0.0 MG
NA
HOH
 9.923
4.305
8.474
 OG
O
OG
 MG
NA
O
SER C:718 C:718 1.0 0.009 H -73.6 -28.3 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -71.1 -30.7 0.0 0.0 0.0 MG
NA
HOH
 9.691
4.268
8.249
 OG
O
OG
 MG
NA
O
SER D:718 C:718 0.0 0.0 H -72.6 -29.3 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -82.2 -24.9 0.0 0.0 0.0 MG
NA
HOH
 9.868
4.813
8.755
 OG
O
OG
 MG
NA
O
SER D:718 C:718 0.0 0.0 H -83.6 -24.7 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -67.3 -10.1 0.0 0.0 0.0 MG
NA
HOH
 9.454
4.596
8.541
 OG
O
OG
 MG
NA
O
SER D:718 C:718 0.0 0.0 H -67.5 -8.0 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -76.3 -27.4 0.0 0.0 0.0 MG
NA
HOH
 9.813
4.617
8.587
 OG
O
OG
 MG
NA
O
SER D:718 C:718 0.0 0.0 H -78.4 -27.0 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -73.3 -30.5 0.0 0.0 0.0 MG
NA
HOH
 9.806
4.599
8.540
 OG
O
OG
 MG
NA
O
SER D:718 C:718 1.0 0.009 H -75.1 -28.6 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 0.0 0.0 H -72.9 -30.8 0.0 0.0 0.0 MG
NA
HOH
 9.618
4.371
8.797
 OG
O
OG
 MG
NA
O
SER D:718 C:718 0.0 0.0 H -76.0 -27.8 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:718 A:718 1.0 0.009 H -71.4 -30.0 1.0 0.009 0.0 MG
NA
HOH
 9.814
4.417
8.207
 OG
O
OG
 MG
NA
O
SER D:718 C:718 0.0 0.0 H -73.1 -28.6 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 SER A:700 A:718 2.0 0.017 H -83.5 18.9 2.0 0.017 0.0 RB
 4.923
 O
 RB
SER D:700 C:718 2.0 0.017 H -83.9 19.2 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 SER A:700 A:718 2.0 0.017 H -53.4 -7.6 2.0 0.017 0.0 RB
 4.741
 O
 RB
SER D:700 C:718 2.0 0.017 H -56.2 -9.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 SER A:694 A:718 3.0 0.026 H -80.9 -24.5 3.0 0.026 0.0
SER D:694 C:718 4.0 0.035 H -80.0 -24.4 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 LEU A:730 A:725 0.0 0.0 H -66.6 -38.2 0.0 0.0 0.0 MG
K
HOH
 9.239
2.982
4.260
 CD1
O
O
 MG
K
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 LEU A:730 A:725 1.0 0.006 H -56.7 -44.4 1.0 0.006 0.0 MF4
MG
K
HOH
 9.881
9.096
3.763
4.976
 CD1
CD1
O
N
 F1
MG
K
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.1 0.0 0.0 0.0 MG
K
TL
 9.240
2.982
2.982
 CD1
O
O
 MG
K
TL
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.2 0.0 0.0 0.0 MG
K
TL
 9.240
2.981
2.981
 CD1
O
O
 MG
K
TL
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.2 0.0 0.0 0.0 MG
K
TL
 9.239
2.982
2.982
 CD1
O
O
 MG
K
TL
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.2 0.0 0.0 0.0 MG
K
TL
 9.238
2.982
2.982
 CD1
O
O
 MG
K
TL
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.3 0.0 0.0 0.0 MG
K
TL
 9.239
2.982
2.982
 CD1
O
O
 MG
K
TL
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.3 0.0 0.0 0.0 MG
K
TL
 9.239
2.982
2.982
 CD1
O
O
 MG
K
TL
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.3 0.0 0.0 0.0 MG
K
TL
 9.239
2.983
2.983
 CD1
O
O
 MG
K
TL
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.3 0.0 0.0 0.0 MG
K
TL
 9.240
2.983
2.983
 CD1
O
O
 MG
K
TL
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.8 -38.1 0.0 0.0 0.0 MG
K
TL
 9.239
2.981
2.981
 CD1
O
O
 MG
K
TL
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.1 0.0 0.0 0.0 MG
K
TL
 9.239
2.982
2.982
 CD1
O
O
 MG
K
TL
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.2 0.0 0.0 0.0 MG
K
TL
 9.239
2.981
2.981
 CD1
O
O
 MG
K
TL
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.2 0.0 0.0 0.0 MG
K
TL
 9.239
2.983
2.983
 CD1
O
O
 MG
K
TL
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.5 -38.3 0.0 0.0 0.0 MG
K
TL
 9.239
2.982
2.982
 CD1
O
O
 MG
K
TL
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.2 0.0 0.0 0.0 MG
K
TL
 9.240
2.983
2.983
 CD1
O
O
 MG
K
TL
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.2 0.0 0.0 0.0 MG
K
RB
 9.239
2.983
2.983
 CD1
O
O
 MG
K
RB
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.3 0.0 0.0 0.0 MG
K
RB
 9.240
2.984
2.984
 CD1
O
O
 MG
K
RB
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.3 0.0 0.0 0.0 MG
K
RB
 9.240
2.981
2.981
 CD1
O
O
 MG
K
RB
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.6 -38.3 0.0 0.0 0.0 MG
K
RB
 9.239
2.983
2.983
 CD1
O
O
 MG
K
RB
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -66.7 -38.3 0.0 0.0 0.0 MG
RB
 9.240
2.982
 CD1
O
 MG
RB
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:730 A:725 0.0 0.0 H -60.6 -38.6 0.0 0.0 0.0 MG
K
HOH
 9.134
2.966
4.668
 CD1
O
O
 MG
K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 LEU A:715 A:715 0.0 0.0 H -57.0 -41.1
af-p50993-f1 1 P50993 88.81 0.0 LEU A:722 A:722 0.0 0.0 H -56.9 -40.1
af-p05023-f1 1 P05023 88.03 0.0 LEU A:725 A:725 0.0 0.0 H -57.1 -41.3