Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42479928 | . | C | A | CCDS12594.1:NM_152296.4:c.2116Ggg>Tgg_NP_689509.1:p.706G>W | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -119.3 | -169.7 | 0.0 | 0.0 | 0.0 |
MG ALF MG ADP HOH |
9.631 6.900 5.654 9.762 7.426 |
C C C C C |
MG F4 MG O1B O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -124.1 | 174.3 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -133.2 | -150.9 | 0.0 | 0.0 | 0.0 |
MG ALF MG ADP HOH |
9.455 6.931 5.475 9.611 7.329 |
C C C CA C |
MG F2 MG O3B O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -124.2 | -178.5 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | GLY | A:714 | A:714 | 0.0 | 0.0 | -153.4 | -178.7 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.441 5.696 |
C CA |
MG O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | GLY | A:714 | A:709 | 2.0 | 0.027 | E | -162.2 | -162.9 | 2.0 | 0.027 | 0.0 |
ADP ALF MG |
9.429 7.210 5.729 |
CA C C |
O3B F3 MG |
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| GLY | D:714 | C:709 | 2.0 | 0.027 | E | -160.0 | -163.4 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | GLY | A:714 | A:709 | 1.0 | 0.013 | -146.9 | 167.0 | 1.0 | 0.013 | 0.0 |
MG |
6.251 |
C |
MG |
|||
| GLY | D:714 | C:709 | 1.0 | 0.013 | -147.4 | 167.4 | NA | NA | NA | ||||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:714 | A:709 | 3.0 | 0.04 | -150.8 | -177.7 | 3.0 | 0.04 | 0.0 |
MG |
6.009 |
C |
MG |
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| GLY | D:714 | C:709 | 4.0 | 0.053 | -150.4 | -178.1 | NA | NA | NA | ||||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:714 | A:709 | 1.0 | 0.013 | -149.9 | 170.7 | 1.0 | 0.013 | 0.0 |
MG |
5.962 |
C |
MG |
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| GLY | D:714 | C:709 | 2.0 | 0.027 | -149.5 | 169.9 | NA | NA | NA | ||||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | GLY | A:714 | A:709 | 0.0 | 0.0 | E | -140.4 | -178.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.355 5.626 |
C C |
MG O |
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| GLY | D:714 | C:709 | 0.0 | 0.0 | E | -140.3 | -179.3 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -142.1 | 173.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.392 5.188 |
C C |
MG O |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -142.1 | 170.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.243 5.311 |
C C |
MG O |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -146.8 | -176.0 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.674 5.420 |
C C |
MG O |
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| GLY | C:709 | C:709 | 1.0 | 0.013 | E | -146.1 | -176.7 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -145.9 | -175.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.541 5.270 |
C C |
MG O |
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| GLY | D:709 | C:709 | 1.0 | 0.013 | E | -146.0 | -176.0 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -143.5 | -179.9 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.516 5.445 |
C CA |
MG O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -143.8 | 179.5 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -149.4 | -178.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.284 5.543 |
C C |
MG O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -149.6 | -179.1 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -139.6 | -179.9 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.521 5.407 |
C C |
MG O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -138.9 | 179.8 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -145.9 | -175.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.582 5.480 |
C C |
MG O |
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| GLY | D:709 | C:709 | 1.0 | 0.013 | E | -145.7 | -176.1 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -140.2 | 178.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.359 5.564 |
C C |
MG O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -142.4 | 179.7 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:709 | A:709 | 0.0 | 0.0 | E | -147.9 | -178.8 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.590 5.179 |
C C |
MG O |
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| GLY | D:709 | C:709 | 0.0 | 0.0 | E | -147.4 | -178.5 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | GLY | A:691 | A:709 | 0.0 | 0.0 | -140.0 | -172.3 | 0.0 | 0.0 | 0.0 |
MG MF4 |
6.078 7.243 |
C CA |
MG F1 |
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| GLY | D:691 | C:709 | 0.0 | 0.0 | -140.5 | -171.0 | NA | NA | NA | ||||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | GLY | A:691 | A:709 | 0.0 | 0.0 | -160.3 | -176.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.992 5.709 |
CA C |
F2 MG |
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| GLY | D:691 | C:709 | 0.0 | 0.0 | -164.6 | -176.9 | NA | NA | NA | ||||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLY | A:685 | A:709 | 3.0 | 0.04 | E | -128.4 | 175.3 | 3.0 | 0.04 | 0.0 |
MG |
5.879 |
C |
MG |
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| GLY | D:685 | C:709 | 3.0 | 0.04 | E | -128.4 | 174.9 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
6.860 5.376 5.119 |
CA C C |
F2 MG O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -160.1 | -179.5 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
6.975 5.510 5.105 |
CA C C |
F2 MG O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.377 |
CA C |
F2 MG |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.861 5.377 |
CA C |
F2 MG |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.3 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.861 5.376 |
CA C |
F2 MG |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.375 |
CA C |
F2 MG |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.859 5.376 |
CA C |
F2 MG |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.5 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.376 |
CA C |
F2 MG |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.3 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.862 5.376 |
CA C |
F2 MG |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.376 |
CA C |
F2 MG |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.376 |
CA C |
F2 MG |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.376 |
CA C |
F2 MG |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.859 5.376 |
CA C |
F2 MG |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.5 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.859 5.376 |
CA C |
F2 MG |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | 180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.861 5.376 |
CA C |
F2 MG |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.377 |
CA C |
F2 MG |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.376 |
CA C |
F2 MG |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.377 |
CA C |
F2 MG |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.377 |
CA C |
F2 MG |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -180.0 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.860 5.376 |
CA C |
F2 MG |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -163.4 | -179.9 | 0.0 | 0.0 | 0.0 |
MF4 MG |
6.861 5.377 |
CA C |
F2 MG |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:721 | A:716 | 0.0 | 0.0 | E | -156.5 | -176.0 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
7.046 5.478 5.212 |
CA C C |
F2 MG O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | GLY | A:706 | A:706 | 0.0 | 0.0 | E | -159.4 | 168.2 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | GLY | A:713 | A:713 | 0.0 | 0.0 | E | -159.3 | 167.5 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | GLY | A:716 | A:716 | 0.0 | 0.0 | E | -161.9 | 167.2 | |