Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42480703 | . | G | A | CCDS12594.1:NM_152296.4:c.1959tgC>tgT_NP_689509.1:p.653C>C | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | CYS | A:656 | A:656 | 9.0 | 0.067 | E | -153.3 | 156.4 | 9.0 | 0.067 | 0.0 |
HOH |
6.938 |
SG |
O |
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| CYS | D:656 | C:656 | 11.0 | 0.081 | E | -161.4 | 146.0 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | CYS | A:656 | A:656 | 11.0 | 0.081 | E | -154.5 | 160.5 | 11.0 | 0.081 | 0.0 |
HOH |
7.684 |
SG |
O |
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| CYS | D:656 | C:656 | 11.0 | 0.081 | E | -160.7 | 139.9 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | CYS | A:661 | A:661 | 11.0 | 0.081 | E | -144.8 | 141.2 | 11.0 | 0.081 | 0.0 | ||||||
| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | CYS | A:661 | A:656 | 9.0 | 0.067 | E | -167.5 | 150.6 | 9.0 | 0.067 | 0.0 | ||||||
| CYS | D:661 | C:656 | 9.0 | 0.067 | E | -167.1 | 151.0 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | CYS | A:661 | A:656 | 12.0 | 0.089 | E | -147.5 | 141.0 | 12.0 | 0.089 | 0.0 | ||||||
| CYS | D:661 | C:656 | 12.0 | 0.089 | E | -147.6 | 140.7 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | CYS | A:661 | A:656 | 8.0 | 0.059 | E | -143.7 | 151.0 | 8.0 | 0.059 | 0.0 | ||||||
| CYS | D:661 | C:656 | 8.0 | 0.059 | E | -144.2 | 150.6 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | CYS | A:661 | A:656 | 12.0 | 0.089 | E | -147.2 | 140.7 | 12.0 | 0.089 | 0.0 | ||||||
| CYS | D:661 | C:656 | 12.0 | 0.089 | E | -147.5 | 140.4 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | CYS | A:661 | A:656 | 14.0 | 0.104 | E | -156.4 | 140.6 | 14.0 | 0.104 | 0.0 | ||||||
| CYS | D:661 | C:656 | 9.0 | 0.067 | E | -158.9 | 144.8 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 10.0 | 0.074 | E | -158.1 | 148.2 | 10.0 | 0.074 | 0.0 | ||||||
| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 8.0 | 0.059 | E | -158.4 | 146.2 | 8.0 | 0.059 | 0.0 | ||||||
| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 6.0 | 0.044 | E | -157.9 | 142.3 | 6.0 | 0.044 | 0.0 | ||||||
| CYS | C:656 | C:656 | 6.0 | 0.044 | E | -157.6 | 143.6 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 7.0 | 0.052 | E | -158.0 | 142.7 | 7.0 | 0.052 | 0.0 | ||||||
| CYS | D:656 | C:656 | 6.0 | 0.044 | E | -157.5 | 143.2 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 10.0 | 0.074 | E | -159.7 | 144.5 | 10.0 | 0.074 | 0.0 | ||||||
| CYS | D:656 | C:656 | 7.0 | 0.052 | E | -159.7 | 144.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 10.0 | 0.074 | E | -153.5 | 139.6 | 10.0 | 0.074 | 0.0 | ||||||
| CYS | D:656 | C:656 | 8.0 | 0.059 | E | -152.8 | 141.1 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 9.0 | 0.067 | E | -155.2 | 148.3 | 9.0 | 0.067 | 0.0 | ||||||
| CYS | D:656 | C:656 | 7.0 | 0.052 | E | -155.7 | 149.3 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 6.0 | 0.044 | E | -158.4 | 141.9 | 6.0 | 0.044 | 0.0 | ||||||
| CYS | D:656 | C:656 | 6.0 | 0.044 | E | -159.3 | 142.5 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 9.0 | 0.067 | E | -155.2 | 146.1 | 9.0 | 0.067 | 0.0 | ||||||
| CYS | D:656 | C:656 | 6.0 | 0.044 | E | -153.3 | 145.2 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | CYS | A:656 | A:656 | 9.0 | 0.067 | E | -158.0 | 142.3 | 9.0 | 0.067 | 0.0 | ||||||
| CYS | D:656 | C:656 | 5.0 | 0.037 | E | -157.4 | 142.7 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | CYS | A:638 | A:656 | 17.0 | 0.126 | -153.9 | 165.9 | 17.0 | 0.126 | 0.0 | |||||||
| CYS | D:638 | C:656 | 17.0 | 0.126 | -153.8 | 166.2 | NA | NA | NA | ||||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | CYS | A:638 | A:656 | 8.0 | 0.059 | E | -167.0 | 147.7 | 8.0 | 0.059 | 0.0 | ||||||
| CYS | D:638 | C:656 | 8.0 | 0.059 | E | -166.3 | 151.0 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | CYS | A:632 | A:656 | 9.0 | 0.067 | -172.1 | 176.8 | 9.0 | 0.067 | 0.0 | |||||||
| CYS | D:632 | C:656 | 9.0 | 0.067 | -171.9 | 177.0 | NA | NA | NA | ||||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.5 | 13.0 | 0.096 | 0.0 |
HOH |
3.191 |
CA |
O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | CYS | A:668 | A:663 | 12.0 | 0.089 | E | -139.7 | 166.6 | 12.0 | 0.089 | 0.0 |
HOH |
3.348 |
CB |
O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.7 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.5 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.7 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.7 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.7 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.5 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.7 | 152.5 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.5 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -143.6 | 152.6 | 13.0 | 0.096 | 0.0 | ||||||
| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | CYS | A:668 | A:663 | 13.0 | 0.096 | E | -139.5 | 152.0 | 13.0 | 0.096 | 0.0 |
HOH |
3.441 |
CA |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | CYS | A:653 | A:653 | 5.0 | 0.037 | E | -139.4 | 149.5 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | CYS | A:660 | A:660 | 11.0 | 0.081 | E | -140.5 | 149.3 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | CYS | A:663 | A:663 | 11.0 | 0.081 | E | -141.9 | 149.8 | |