Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42482193 . G A CCDS12594.1:NM_152296.4:c.1838aCg>aTg_NP_689509.1:p.613T>M Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:616 A:616 2.0 0.014 H -54.8 -38.8 2.0 0.014 0.0 ALF
ADP
HOH
 8.762
7.077
9.698
 CG2
OG1
N
 F1
O3'
O
THR D:616 C:616 0.0 0.0 H -71.4 -41.0 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:616 A:616 1.0 0.007 H -61.7 -41.7 1.0 0.007 0.0 ALF
ADP
HOH
 8.951
7.440
9.805
 CG2
CB
N
 F1
O3'
O
THR D:616 C:616 0.0 0.0 H -67.4 -31.8 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 THR A:621 A:621 9.0 0.064 H -78.8 -40.5 9.0 0.064 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 THR A:621 A:616 0.0 0.0 H -58.5 -48.1 0.0 0.0 0.0 ADP
ALF
 7.615
7.639
 CB
CG2
 O3'
F2
THR D:621 C:616 0.0 0.0 H -57.3 -47.6 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 THR A:621 A:616 8.0 0.057 H -80.2 -39.3 8.0 0.057 0.0
THR D:621 C:616 13.0 0.093 H -80.2 -39.1 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:621 A:616 13.0 0.093 H -75.8 -46.9 13.0 0.093 0.0
THR D:621 C:616 13.0 0.093 H -75.6 -47.0 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:621 A:616 12.0 0.086 H -78.8 -39.0 12.0 0.086 0.0
THR D:621 C:616 20.0 0.143 H -78.4 -39.2 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 THR A:621 A:616 10.0 0.071 H -90.4 -32.9 10.0 0.071 0.0
THR D:621 C:616 5.0 0.036 H -88.0 -35.5 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 6.0 0.043 H -82.6 -36.2 6.0 0.043 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 5.0 0.036 H -83.1 -33.7 5.0 0.036 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 12.0 0.086 H -94.0 -34.3 12.0 0.086 0.0
THR C:616 C:616 8.0 0.057 H -93.1 -34.3 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 10.0 0.071 H -92.6 -35.3 10.0 0.071 0.0
THR D:616 C:616 9.0 0.064 H -92.9 -35.0 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 19.0 0.136 H -91.0 -34.9 19.0 0.136 0.0
THR D:616 C:616 8.0 0.057 H -88.1 -37.2 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 15.0 0.107 H -90.4 -38.2 15.0 0.107 0.0
THR D:616 C:616 6.0 0.043 H -89.4 -39.2 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 11.0 0.079 H -92.6 -37.4 11.0 0.079 0.0
THR D:616 C:616 6.0 0.043 H -92.6 -38.3 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 11.0 0.079 H -92.8 -35.5 11.0 0.079 0.0
THR D:616 C:616 7.0 0.05 H -92.4 -36.0 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 13.0 0.093 H -100.3 -35.4 13.0 0.093 0.0
THR D:616 C:616 7.0 0.05 H -97.2 -36.6 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:616 A:616 11.0 0.079 H -92.3 -34.6 11.0 0.079 0.0
THR D:616 C:616 9.0 0.064 H -92.2 -35.2 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 THR A:598 A:616 35.0 0.25 H -54.0 -60.3 35.0 0.25 0.0 MF4
 8.430
 CG2
 F4
THR D:598 C:616 31.0 0.221 H -54.2 -60.4 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 THR A:598 A:616 35.0 0.25 H -67.8 -64.2 35.0 0.25 0.0 MF4
 9.055
 CG2
 F4
THR D:598 C:616 34.0 0.243 H -64.8 -65.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:592 A:616 17.0 0.121 H -71.1 -34.2 17.0 0.121 0.0
THR D:592 C:616 17.0 0.121 H -71.5 -33.5 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 THR A:628 A:623 36.0 0.257 H -70.0 -44.5 36.0 0.257 0.0 MF4
HOH
 7.975
3.242
 CG2
CG2
 F3
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 THR A:628 A:623 37.0 0.264 H -66.6 -48.7 37.0 0.264 0.0 MF4
HOH
 8.340
3.498
 CG2
CG2
 F4
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 36.0 0.257 H -70.0 -44.5 36.0 0.257 0.0 MF4
 7.974
 CG2
 F3
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.4 35.0 0.25 0.0 MF4
 7.974
 CG2
 F3
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -69.9 -44.5 35.0 0.25 0.0 MF4
 7.976
 CG2
 F3
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 36.0 0.257 H -69.8 -44.5 36.0 0.257 0.0 MF4
 7.975
 CG2
 F3
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 36.0 0.257 H -69.9 -44.5 36.0 0.257 0.0 MF4
 7.975
 CG2
 F3
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.1 -44.5 35.0 0.25 0.0 MF4
 7.974
 CG2
 F3
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -69.9 -44.5 35.0 0.25 0.0 MF4
 7.975
 CG2
 F3
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.5 35.0 0.25 0.0 MF4
 7.975
 CG2
 F3
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.4 35.0 0.25 0.0 MF4
 7.974
 CG2
 F3
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 36.0 0.257 H -70.0 -44.5 36.0 0.257 0.0 MF4
 7.974
 CG2
 F3
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.5 35.0 0.25 0.0 MF4
 7.974
 CG2
 F3
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -69.9 -44.5 35.0 0.25 0.0 MF4
 7.975
 CG2
 F3
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.4 35.0 0.25 0.0 MF4
 7.976
 CG2
 F3
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.5 35.0 0.25 0.0 MF4
 7.975
 CG2
 F3
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -69.9 -44.5 35.0 0.25 0.0 MF4
 7.974
 CG2
 F3
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -69.9 -44.5 35.0 0.25 0.0 MF4
 7.975
 CG2
 F3
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 36.0 0.257 H -69.9 -44.5 36.0 0.257 0.0 MF4
 7.975
 CG2
 F3
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 35.0 0.25 H -70.0 -44.4 35.0 0.25 0.0 MF4
 7.975
 CG2
 F3
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 36.0 0.257 H -69.9 -44.5 36.0 0.257 0.0 MF4
 7.975
 CG2
 F3
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:628 A:623 38.0 0.271 H -66.8 -52.1 38.0 0.271 0.0 MF4
HOH
 7.908
3.202
 CG2
CG2
 F3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 THR A:613 A:613 28.0 0.2 H -65.2 -42.2
af-p50993-f1 1 P50993 88.81 0.0 THR A:620 A:620 28.0 0.2 H -66.8 -42.7
af-p05023-f1 1 P05023 88.03 0.0 THR A:623 A:623 27.0 0.193 H -61.9 -45.9