Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42486143 | . | G | A | CCDS12594.1:NM_152296.4:c.1109aCc>aTc_NP_689509.1:p.370T>I | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -134.0 | -69.0 | 0.0 | 0.0 | 0.0 |
MG ALF MG ADP HOH |
8.883 4.553 4.719 7.620 6.032 |
OG1 OG1 OG1 OG1 OG1 |
MG F4 MG O3B O |
||
| THR | D:373 | C:373 | 0.0 | 0.0 | I | -70.6 | -86.0 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -136.4 | -70.3 | 0.0 | 0.0 | 0.0 |
MG ALF MG ADP HOH |
8.729 5.090 4.368 7.466 6.156 |
OG1 OG1 OG1 OG1 N |
MG F4 MG O3B O |
||
| THR | D:373 | C:373 | 0.0 | 0.0 | I | -81.6 | -83.9 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | THR | A:378 | A:378 | 0.0 | 0.0 | I | -113.0 | -72.5 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.317 5.542 |
OG1 OG1 |
MG O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | THR | A:378 | A:373 | 0.0 | 0.0 | I | -108.9 | -72.6 | 0.0 | 0.0 | 0.0 |
ADP ALF MG |
7.591 5.266 4.278 |
OG1 OG1 OG1 |
O3B F3 MG |
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| THR | D:378 | C:373 | 0.0 | 0.0 | I | -109.0 | -73.7 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | THR | A:378 | A:373 | 0.0 | 0.0 | I | -105.2 | -74.2 | 0.0 | 0.0 | 0.0 |
MG |
4.733 |
OG1 |
MG |
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| THR | D:378 | C:373 | 0.0 | 0.0 | I | -104.9 | -73.8 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | THR | A:378 | A:373 | 0.0 | 0.0 | T | -121.6 | -74.4 | 0.0 | 0.0 | 0.0 |
MG |
4.431 |
OG1 |
MG |
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| THR | D:378 | C:373 | 0.0 | 0.0 | I | -121.8 | -74.3 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | THR | A:378 | A:373 | 0.0 | 0.0 | I | -111.7 | -71.2 | 0.0 | 0.0 | 0.0 |
MG |
4.692 |
OG1 |
MG |
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| THR | D:378 | C:373 | 0.0 | 0.0 | I | -111.4 | -70.9 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | THR | A:378 | A:373 | 0.0 | 0.0 | I | -90.9 | -64.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.478 5.722 |
OG1 OG1 |
MG O |
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| THR | D:378 | C:373 | 0.0 | 0.0 | I | -93.4 | -65.5 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -90.4 | -59.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.582 5.393 |
OG1 OG1 |
MG O |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -84.5 | -62.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.221 5.293 |
OG1 OG1 |
MG O |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -111.2 | -65.8 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.665 5.403 |
OG1 OG1 |
MG O |
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| THR | C:373 | C:373 | 0.0 | 0.0 | I | -111.0 | -66.4 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -111.8 | -63.7 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.615 5.348 |
OG1 OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -112.5 | -65.7 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -99.9 | -62.7 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.681 5.500 |
OG1 OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -98.8 | -66.3 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -100.1 | -61.7 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.524 5.740 |
OG1 OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -97.4 | -63.6 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -87.8 | -62.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.582 5.453 |
OG1 OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -89.0 | -61.9 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -112.0 | -65.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.553 5.401 |
OG1 OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -110.9 | -65.5 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -88.3 | -65.9 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.528 5.705 |
N OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -89.6 | -66.3 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | THR | A:373 | A:373 | 0.0 | 0.0 | I | -112.5 | -61.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.749 5.314 |
OG1 OG1 |
MG O |
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| THR | D:373 | C:373 | 0.0 | 0.0 | I | -111.5 | -62.1 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | THR | A:355 | A:373 | 0.0 | 0.0 | I | -101.5 | -76.4 | 0.0 | 0.0 | 0.0 |
MG MF4 |
5.339 6.440 |
N OG1 |
MG F2 |
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| THR | D:355 | C:373 | 0.0 | 0.0 | I | -101.1 | -77.0 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | THR | A:355 | A:373 | 0.0 | 0.0 | I | -93.0 | -75.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.906 4.794 |
OG1 OG1 |
F2 MG |
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| THR | D:355 | C:373 | 0.0 | 0.0 | I | -93.9 | -76.1 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | THR | A:349 | A:373 | 0.0 | 0.0 | I | -102.6 | -75.4 | 0.0 | 0.0 | 0.0 |
MG |
5.060 |
OG1 |
MG |
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| THR | D:349 | C:373 | 0.0 | 0.0 | I | -102.6 | -74.8 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
5.556 4.179 5.235 |
OG1 OG1 OG1 |
F2 MG O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -109.5 | -70.2 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
5.493 4.145 5.223 |
OG1 OG1 OG1 |
F2 MG O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.8 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.179 |
OG1 OG1 |
F2 MG |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.179 |
OG1 OG1 |
F2 MG |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.8 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.179 |
OG1 OG1 |
F2 MG |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.177 |
OG1 OG1 |
F2 MG |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.555 4.178 |
OG1 OG1 |
F2 MG |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.178 |
OG1 OG1 |
F2 MG |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.6 | -75.8 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.178 |
OG1 OG1 |
F2 MG |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.8 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.179 |
OG1 OG1 |
F2 MG |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.6 | -75.8 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.178 |
OG1 OG1 |
F2 MG |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.8 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.177 |
OG1 OG1 |
F2 MG |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.8 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.8 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.179 |
OG1 OG1 |
F2 MG |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.7 | -75.7 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | I | -113.8 | -75.6 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.557 4.178 |
OG1 OG1 |
F2 MG |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | THR | A:385 | A:380 | 0.0 | 0.0 | T | -111.9 | -68.4 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
5.622 4.327 5.158 |
OG1 OG1 OG1 |
F2 MG O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | THR | A:370 | A:370 | 0.0 | 0.0 | I | -97.0 | -68.9 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | THR | A:378 | A:378 | 0.0 | 0.0 | I | -100.0 | -69.2 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | THR | A:380 | A:380 | 0.0 | 0.0 | I | -96.7 | -70.1 | |