Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42486240 . C A CCDS12594.1:NM_152296.4:c.1012Gcc>Tcc_NP_689509.1:p.338A>S Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ALA A:341 A:341 8.0 0.07 H -66.0 -24.0 8.0 0.07 0.0
ALA D:341 C:341 9.0 0.078 H -47.3 -56.9 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ALA A:341 A:341 7.0 0.061 H -69.2 -28.1 7.0 0.061 0.0
ALA D:341 C:341 8.0 0.07 H -51.1 -60.3 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 ALA A:346 A:346 25.0 0.217 H -60.7 -33.5 25.0 0.217 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 ALA A:346 A:341 4.0 0.035 H -63.5 -43.0 4.0 0.035 0.0
ALA D:346 C:341 4.0 0.035 H -64.0 -42.3 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 ALA A:346 A:341 12.0 0.104 H -59.6 -35.7 12.0 0.104 0.0
ALA D:346 C:341 12.0 0.104 H -58.7 -36.6 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ALA A:346 A:341 18.0 0.157 H -67.5 -18.9 18.0 0.157 0.0
ALA D:346 C:341 16.0 0.139 H -67.4 -18.7 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ALA A:346 A:341 20.0 0.174 H -59.7 -33.3 20.0 0.174 0.0
ALA D:346 C:341 17.0 0.148 H -59.5 -33.4 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 ALA A:346 A:341 14.0 0.122 H -66.0 -31.9 14.0 0.122 0.0 PCW
 9.823
 C
 O1P
ALA D:346 C:341 14.0 0.122 H -66.8 -30.7 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 13.0 0.113 H -69.3 -33.7 13.0 0.113 0.0 PCW
 9.204
 N
 O2P
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 10.0 0.087 H -64.4 -31.4 10.0 0.087 0.0 PCW
 9.986
 C
 O1P
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 13.0 0.113 H -66.5 -29.3 13.0 0.113 0.0 PCW
 9.695
 C
 C7
ALA C:341 C:341 15.0 0.13 H -66.7 -27.7 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 13.0 0.113 H -66.9 -29.5 13.0 0.113 0.0 PCW
PCW
 9.783
8.396
 C
C
 O1P
O2P
ALA D:341 C:341 15.0 0.13 H -66.9 -27.4 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 16.0 0.139 H -63.5 -26.0 16.0 0.139 0.0 PCW
 9.305
 C
 O1P
ALA D:341 C:341 17.0 0.148 H -64.4 -26.9 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 12.0 0.104 H -70.3 -27.1 12.0 0.104 0.0 PCW
 9.621
 CB
 O1P
ALA D:341 C:341 15.0 0.13 H -68.2 -29.1 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 15.0 0.13 H -63.6 -34.0 15.0 0.13 0.0 PCW
 9.946
 C
 O1P
ALA D:341 C:341 15.0 0.13 H -63.2 -33.7 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 13.0 0.113 H -66.9 -29.0 13.0 0.113 0.0
ALA D:341 C:341 15.0 0.13 H -66.9 -27.9 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 16.0 0.139 H -64.5 -32.6 16.0 0.139 0.0 PCW
 9.926
 C
 O1P
ALA D:341 C:341 18.0 0.157 H -64.4 -32.5 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:341 A:341 11.0 0.096 H -66.2 -28.8 11.0 0.096 0.0 PCW
 9.725
 C
 O1P
ALA D:341 C:341 15.0 0.13 H -65.7 -27.9 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 ALA A:323 A:341 13.0 0.113 H -96.3 -65.8 13.0 0.113 0.0
ALA D:323 C:341 18.0 0.157 H -76.2 -72.7 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 ALA A:323 A:341 7.0 0.061 H -61.6 -74.9 7.0 0.061 0.0
ALA D:323 C:341 5.0 0.043 H -91.9 -67.3 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ALA A:317 A:341 14.0 0.122 H -65.7 -26.6 14.0 0.122 0.0
ALA D:317 C:341 14.0 0.122 H -65.1 -27.1 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 ALA A:353 A:348 14.0 0.122 H -64.8 -31.6 14.0 0.122 0.0 HOH
 6.126
 CB
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 ALA A:353 A:348 17.0 0.148 H -50.6 -40.3 17.0 0.148 0.0 HOH
 5.768
 CB
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.6 14.0 0.122 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.6 14.0 0.122 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 13.0 0.113 H -64.8 -31.7 13.0 0.113 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 13.0 0.113 H -64.9 -31.6 13.0 0.113 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.9 -31.5 14.0 0.122 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.6 14.0 0.122 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.7 14.0 0.122 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.9 -31.6 14.0 0.122 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.9 -31.6 14.0 0.122 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.8 -31.6 14.0 0.122 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.9 -31.6 14.0 0.122 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 14.0 0.122 H -64.7 -31.7 14.0 0.122 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:353 A:348 15.0 0.13 H -64.5 -32.1 15.0 0.13 0.0 HOH
 6.072
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 ALA A:338 A:338 12.0 0.104 H -57.6 -42.1
af-p50993-f1 1 P50993 88.81 0.0 ALA A:346 A:346 11.0 0.096 H -57.6 -42.3
af-p05023-f1 1 P05023 88.03 0.0 ALA A:348 A:348 13.0 0.113 H -57.5 -43.2