Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42486248 . G A CCDS12594.1:NM_152296.4:c.1004aCg>aTg_NP_689509.1:p.335T>M Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:338 A:338 6.0 0.043 H -52.5 -37.6 6.0 0.043 0.0 PC1
 5.584
 CG2
 O12
THR D:338 C:338 1.0 0.007 H -59.9 -30.2 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:338 A:338 6.0 0.043 H -62.0 -40.6 6.0 0.043 0.0 PC1
 5.713
 CG2
 O12
THR D:338 C:338 1.0 0.007 H -54.7 -34.0 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 THR A:343 A:343 4.0 0.029 H -61.4 -40.3 4.0 0.029 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 THR A:343 A:338 2.0 0.014 H -60.3 -42.9 2.0 0.014 0.0
THR D:343 C:338 1.0 0.007 H -59.2 -43.5 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 THR A:343 A:338 5.0 0.036 H -59.6 -41.5 5.0 0.036 0.0
THR D:343 C:338 5.0 0.036 H -59.3 -41.1 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:343 A:338 4.0 0.029 H -63.0 -36.2 4.0 0.029 0.0
THR D:343 C:338 4.0 0.029 H -62.4 -35.6 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:343 A:338 6.0 0.043 H -61.6 -41.4 6.0 0.043 0.0
THR D:343 C:338 4.0 0.029 H -61.7 -41.3 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 THR A:343 A:338 4.0 0.029 H -65.6 -36.3 4.0 0.029 0.0 PCW
PCW
 5.830
8.698
 CG2
C
 O1P
O2P
THR D:343 C:338 5.0 0.036 H -67.4 -34.8 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 4.0 0.029 H -63.3 -39.3 4.0 0.029 0.0 PCW
PCW
PCW
 6.143
7.910
4.806
 CG2
O
CG2
 O1P
O1P
O2P
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 3.0 0.021 H -65.5 -43.1 3.0 0.021 0.0 PCW
PCW
 6.057
7.418
 CG2
CG2
 O1P
O1P
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 18.0 0.129 H -64.6 -39.6 18.0 0.129 0.0 PCW
PCW
 6.946
8.253
 CG2
CG2
 O1P
C7
THR C:338 C:338 3.0 0.021 H -63.8 -39.3 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 5.0 0.036 H -64.0 -39.7 5.0 0.036 0.0 PCW
PCW
 5.333
6.287
 CG2
O
 O1P
O2P
THR D:338 C:338 2.0 0.014 H -65.0 -39.0 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 3.0 0.021 H -66.6 -40.8 3.0 0.021 0.0 PCW
PCW
 5.744
8.678
 CG2
O
 O1P
O2P
THR D:338 C:338 4.0 0.029 H -67.5 -38.0 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 3.0 0.021 H -62.0 -38.6 3.0 0.021 0.0 PCW
PCW
 5.519
9.471
 CG2
O
 O1P
O2P
THR D:338 C:338 3.0 0.021 H -62.5 -35.4 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 4.0 0.029 H -67.7 -38.2 4.0 0.029 0.0 PCW
PCW
 6.405
8.567
 CG2
O
 O1P
O2P
THR D:338 C:338 5.0 0.036 H -67.7 -37.3 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 5.0 0.036 H -63.9 -39.6 5.0 0.036 0.0 PCW
 6.887
 CG2
 O1P
THR D:338 C:338 3.0 0.021 H -64.6 -37.3 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 5.0 0.036 H -62.8 -39.8 5.0 0.036 0.0 PCW
PCW
 5.681
9.975
 CG2
O
 O1P
O2P
THR D:338 C:338 6.0 0.043 H -64.2 -36.5 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:338 A:338 5.0 0.036 H -64.1 -41.8 5.0 0.036 0.0 PCW
PCW
 5.323
9.441
 CG2
C
 O1P
O2P
THR D:338 C:338 4.0 0.029 H -65.1 -38.7 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 THR A:320 A:338 28.0 0.2 H -30.2 -35.1 28.0 0.2 0.0
THR D:320 C:338 24.0 0.171 H -35.7 -31.3 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 THR A:320 A:338 17.0 0.121 H -34.9 -13.9 17.0 0.121 0.0
THR D:320 C:338 19.0 0.136 H -48.8 -17.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:314 A:338 9.0 0.064 H -45.5 -51.5 9.0 0.064 0.0
THR D:314 C:338 9.0 0.064 H -45.3 -51.9 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0 HOH
 6.758
 OG1
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 THR A:350 A:345 24.0 0.171 H -57.8 -44.7 24.0 0.171 0.0 HOH
 6.793
 CG2
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.8 32.0 0.229 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.8 32.0 0.229 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.3 -45.6 32.0 0.229 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.2 -45.7 32.0 0.229 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.3 -45.6 32.0 0.229 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 32.0 0.229 H -52.1 -45.7 32.0 0.229 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:350 A:345 31.0 0.221 H -54.7 -45.7 31.0 0.221 0.0 HOH
 6.798
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 THR A:335 A:335 31.0 0.221 H -61.2 -40.0
af-p50993-f1 1 P50993 88.81 0.0 THR A:343 A:343 46.0 0.329 H -62.0 -40.3
af-p05023-f1 1 P05023 88.03 0.0 THR A:345 A:345 28.0 0.2 H -61.3 -39.9