Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42486254 . C A CCDS12594.1:NM_152296.4:c.998tGt>tTt_NP_689509.1:p.333C>F Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 CYS A:336 A:336 5.0 0.037 H -53.1 -45.4 5.0 0.037 0.0 PC1
HOH
 9.280
9.081
 N
CB
 O14
O
CYS D:336 C:336 3.0 0.022 H -55.6 -49.9 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 CYS A:336 A:336 3.0 0.022 H -58.1 -39.8 3.0 0.022 0.0 PC1
 9.414
 N
 O14
CYS D:336 C:336 4.0 0.03 H -50.9 -56.7 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 CYS A:341 A:341 3.0 0.022 H -60.5 -56.9 3.0 0.022 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 CYS A:341 A:336 0.0 0.0 H -50.7 -54.0 0.0 0.0 0.0
CYS D:341 C:336 0.0 0.0 H -51.4 -53.6 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 CYS A:341 A:336 1.0 0.007 H -51.1 -57.6 1.0 0.007 0.0
CYS D:341 C:336 1.0 0.007 H -51.4 -57.5 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 CYS A:341 A:336 2.0 0.015 H -58.6 -56.1 2.0 0.015 0.0
CYS D:341 C:336 2.0 0.015 H -58.2 -56.2 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 CYS A:341 A:336 2.0 0.015 H -53.9 -58.0 2.0 0.015 0.0
CYS D:341 C:336 3.0 0.022 H -54.4 -58.2 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 CYS A:341 A:336 0.0 0.0 H -60.5 -42.1 0.0 0.0 0.0
CYS D:341 C:336 0.0 0.0 H -61.5 -42.8 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -58.7 -44.7 0.0 0.0 0.0 PCW
PCW
 9.223
6.975
 N
N
 O2
C32
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -60.3 -54.9 0.0 0.0 0.0 PCW
 9.670
 O
 O2P
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 1.0 0.007 H -58.1 -53.1 1.0 0.007 0.0 PCW
 9.252
 N
 O1P
CYS C:336 C:336 2.0 0.015 H -59.6 -52.1 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -58.2 -53.2 0.0 0.0 0.0 PCW
 8.840
 O
 O2P
CYS D:336 C:336 0.0 0.0 H -60.6 -50.5 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 1.0 0.007 H -60.0 -49.7 1.0 0.007 0.0 PCW
 9.375
 N
 C31
CYS D:336 C:336 2.0 0.015 H -60.1 -48.0 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 1.0 0.007 H -55.5 -38.5 1.0 0.007 0.0
CYS D:336 C:336 0.0 0.0 H -55.7 -39.8 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -59.1 -53.1 0.0 0.0 0.0 PCW
 8.542
 N
 O31
CYS D:336 C:336 2.0 0.015 H -59.2 -53.4 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -59.2 -54.2 0.0 0.0 0.0
CYS D:336 C:336 2.0 0.015 H -60.4 -51.5 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -57.9 -53.7 0.0 0.0 0.0
CYS D:336 C:336 0.0 0.0 H -57.9 -53.2 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:336 A:336 0.0 0.0 H -59.1 -52.6 0.0 0.0 0.0 PCW
 9.625
 N
 O2
CYS D:336 C:336 1.0 0.007 H -61.0 -50.3 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 CYS A:318 A:336 0.0 0.0 H -53.4 -30.8 0.0 0.0 0.0
CYS D:318 C:336 0.0 0.0 H -65.8 -59.8 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 CYS A:318 A:336 0.0 0.0 H -46.7 -42.6 0.0 0.0 0.0
CYS D:318 C:336 0.0 0.0 H -67.9 -43.1 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 CYS A:312 A:336 1.0 0.007 H -56.5 -63.6 1.0 0.007 0.0
CYS D:312 C:336 2.0 0.015 H -57.1 -64.4 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0 HOH
 8.446
 N
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 CYS A:348 A:343 1.0 0.007 H -61.0 -53.4 1.0 0.007 0.0 HOH
 9.406
 N
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.9 1.0 0.007 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.8 1.0 0.007 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.7 1.0 0.007 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.8 1.0 0.007 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.8 1.0 0.007 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.7 1.0 0.007 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.8 1.0 0.007 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.8 1.0 0.007 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.0 -42.9 1.0 0.007 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.7 1.0 0.007 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.7 1.0 0.007 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.7 1.0 0.007 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.7 1.0 0.007 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 1.0 0.007 H -62.1 -42.7 1.0 0.007 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:348 A:343 2.0 0.015 H -58.3 -49.6 2.0 0.015 0.0 HOH
 8.638
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 CYS A:333 A:333 1.0 0.007 H -57.2 -46.9
af-p50993-f1 1 P50993 88.81 0.0 CYS A:341 A:341 1.0 0.007 H -56.3 -47.5
af-p05023-f1 1 P05023 88.03 0.0 CYS A:343 A:343 1.0 0.007 H -56.7 -47.6