Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489072 . T A CCDS12594.1:NM_152296.4:c.991Act>Tct_NP_689509.1:p.331T>S Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:334 A:334 26.0 0.186 H -56.6 -44.7 26.0 0.186 0.0 PC1
HOH
 9.393
6.418
 O
N
 O12
O
THR D:334 C:334 18.0 0.129 H -54.8 -58.6 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:334 A:334 25.0 0.179 H -56.6 -47.8 25.0 0.179 0.0 PC1
EFO
 9.498
5.939
 O
OG1
 O12
C1D
THR D:334 C:334 20.0 0.143 H -51.0 -46.6 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 THR A:339 A:339 16.0 0.114 H -54.9 -44.7 16.0 0.114 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 THR A:339 A:334 22.0 0.157 H -56.3 -38.1 22.0 0.157 0.0
THR D:339 C:334 22.0 0.157 H -55.8 -38.1 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 THR A:339 A:334 16.0 0.114 H -58.9 -47.0 16.0 0.114 0.0
THR D:339 C:334 17.0 0.121 H -59.6 -46.7 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:339 A:334 13.0 0.093 H -54.6 -44.9 13.0 0.093 0.0
THR D:339 C:334 13.0 0.093 H -54.2 -45.7 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:339 A:334 17.0 0.121 H -56.1 -46.9 17.0 0.121 0.0
THR D:339 C:334 17.0 0.121 H -56.5 -46.7 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 THR A:339 A:334 15.0 0.107 H -62.2 -45.8 15.0 0.107 0.0 PCW
 9.287
 CG2
 O31
THR D:339 C:334 16.0 0.114 H -61.1 -45.4 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 13.0 0.093 H -61.5 -52.7 13.0 0.093 0.0 PCW
PCW
 8.873
7.397
 CG2
C
 C32
O31
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 16.0 0.114 H -61.4 -53.4 16.0 0.114 0.0 PCW
 8.749
 CG2
 C32
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 22.0 0.157 H -62.4 -48.3 22.0 0.157 0.0 PCW
 8.103
 CG2
 C32
THR C:334 C:334 13.0 0.093 H -62.5 -47.5 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 18.0 0.129 H -62.2 -47.1 18.0 0.129 0.0 PCW
PCW
 8.935
9.797
 CG2
O
 O31
O2P
THR D:334 C:334 14.0 0.1 H -62.1 -46.3 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 17.0 0.121 H -61.4 -40.9 17.0 0.121 0.0 PCW
 9.568
 CG2
 O31
THR D:334 C:334 13.0 0.093 H -61.4 -40.6 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 20.0 0.143 H -61.2 -48.7 20.0 0.143 0.0 PCW
 9.678
 CG2
 O3
THR D:334 C:334 16.0 0.114 H -61.5 -49.3 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 16.0 0.114 H -59.9 -48.6 16.0 0.114 0.0 PCW
 9.365
 CG2
 O31
THR D:334 C:334 15.0 0.107 H -60.3 -49.5 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 18.0 0.129 H -63.0 -46.4 18.0 0.129 0.0 PCW
 8.863
 CG2
 O31
THR D:334 C:334 14.0 0.1 H -63.9 -45.7 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 16.0 0.114 H -60.0 -44.4 16.0 0.114 0.0 PCW
 9.541
 CG2
 O31
THR D:334 C:334 17.0 0.121 H -60.3 -44.9 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:334 A:334 18.0 0.129 H -62.8 -45.7 18.0 0.129 0.0 PCW
 9.031
 CG2
 O31
THR D:334 C:334 15.0 0.107 H -62.3 -46.8 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 THR A:316 A:334 5.0 0.036 H -45.9 -53.6 5.0 0.036 0.0
THR D:316 C:334 4.0 0.029 H -50.6 -82.4 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 THR A:316 A:334 4.0 0.029 H -39.0 -40.4 4.0 0.029 0.0
THR D:316 C:334 4.0 0.029 H -41.2 -63.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:310 A:334 24.0 0.171 H -54.4 -49.4 24.0 0.171 0.0
THR D:310 C:334 25.0 0.179 H -54.6 -49.3 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0 HOH
 3.589
 OG1
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 THR A:346 A:341 2.0 0.014 H -69.5 -52.8 2.0 0.014 0.0 HOH
 4.538
 OG1
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.2 3.0 0.021 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.9 -46.2 3.0 0.021 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.2 3.0 0.021 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.9 -46.2 3.0 0.021 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.4 3.0 0.021 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.9 -46.3 3.0 0.021 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.9 -46.1 3.0 0.021 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.9 -46.2 3.0 0.021 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.9 -46.3 3.0 0.021 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.3 3.0 0.021 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.8 -46.2 3.0 0.021 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 3.0 0.021 H -54.7 -46.4 3.0 0.021 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 THR A:346 A:341 2.0 0.014 H -54.0 -49.1 2.0 0.014 0.0 HOH
 3.885
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 THR A:331 A:331 26.0 0.186 H -63.9 -42.7
af-p50993-f1 1 P50993 88.81 0.0 THR A:339 A:339 14.0 0.1 H -62.2 -41.3
af-p05023-f1 1 P05023 88.03 0.0 THR A:341 A:341 17.0 0.121 H -61.0 -43.0