Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489086 . A C CCDS12594.1:NM_152296.4:c.977cTg>cGg_NP_689509.1:p.326L>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:329 A:329 5.0 0.029 H -24.8 -56.8 5.0 0.029 0.0 NA
PC1
HOH
 8.747
9.420
6.759
 N
CD2
O
 NA
O32
O
LEU D:329 C:329 3.0 0.018 H -33.9 -52.0 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:329 A:329 7.0 0.041 H -27.3 -58.2 7.0 0.041 0.0 NA
PC1
EFO
HOH
 8.713
9.524
6.699
7.985
 N
CD2
CD2
N
 NA
O32
O36
O
LEU D:329 C:329 4.0 0.024 H -41.8 -48.1 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 LEU A:334 A:334 3.0 0.018 H -69.1 -31.2 3.0 0.018 0.0 MG
HOH
 7.531
6.213
 N
N
 MG
O
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 LEU A:334 A:329 3.0 0.018 H -52.7 -41.1 3.0 0.018 0.0 NA
 8.124
 N
 NA
LEU D:334 C:329 4.0 0.024 H -52.9 -40.5 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 LEU A:334 A:329 0.0 0.0 H -65.9 -13.4 0.0 0.0 0.0 MG
HOH
 7.901
6.397
 N
N
 MG
O
LEU D:334 C:329 0.0 0.0 H -66.1 -13.7 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LEU A:334 A:329 2.0 0.012 H -62.7 -31.6 2.0 0.012 0.0 K
K
 6.681
8.707
 N
N
 K
K
LEU D:334 C:329 1.0 0.006 H -62.4 -32.0 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LEU A:334 A:329 0.0 0.0 H -66.2 -28.2 0.0 0.0 0.0 MG
HOH
 7.797
6.394
 N
N
 MG
O
LEU D:334 C:329 0.0 0.0 H -66.9 -27.9 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 LEU A:334 A:329 0.0 0.0 H -73.9 -27.0 0.0 0.0 0.0 MG
HOH
 7.195
6.072
 N
N
 MG
O
LEU D:334 C:329 0.0 0.0 H -75.5 -26.0 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -71.1 -21.7 0.0 0.0 0.0 MG
PCW
HOH
 7.698
9.838
9.258
 N
O
N
 MG
O31
O
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -68.6 -24.6 0.0 0.0 0.0 MG
HOH
 7.356
7.045
 N
N
 MG
O
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -60.8 -20.4 0.0 0.0 0.0 MG
HOH
 7.568
6.535
 N
N
 MG
O
LEU C:329 C:329 0.0 0.0 H -61.1 -22.6 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -61.1 -20.7 0.0 0.0 0.0 MG
RB
HOH
 8.080
7.207
4.084
 N
N
N
 MG
RB
O
LEU D:329 C:329 0.0 0.0 H -61.2 -21.6 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -75.2 -26.4 0.0 0.0 0.0 MG
HOH
 7.401
6.288
 N
N
 MG
O
LEU D:329 C:329 0.0 0.0 H -76.4 -26.1 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -59.6 -26.6 0.0 0.0 0.0 MG
HOH
 7.484
6.614
 N
N
 MG
O
LEU D:329 C:329 1.0 0.006 H -62.0 -26.5 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -70.4 -27.7 0.0 0.0 0.0 MG
HOH
 7.439
6.085
 N
N
 MG
O
LEU D:329 C:329 0.0 0.0 H -72.0 -28.6 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 1.0 0.006 H -59.9 -21.3 1.0 0.006 0.0 MG
HOH
 7.631
6.743
 N
N
 MG
O
LEU D:329 C:329 0.0 0.0 H -59.4 -22.6 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 0.0 0.0 H -65.2 -23.8 0.0 0.0 0.0 MG
HOH
 7.483
6.484
 N
N
 MG
O
LEU D:329 C:329 0.0 0.0 H -68.2 -22.6 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:329 A:329 1.0 0.006 H -62.2 -21.3 1.0 0.006 0.0 MG
HOH
 7.354
6.232
 N
N
 MG
O
LEU D:329 C:329 0.0 0.0 H -63.2 -22.6 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 LEU A:311 A:329 2.0 0.012 S -167.6 -54.9 2.0 0.012 0.0 RB
RB
 7.527
8.661
 CB
CB
 RB
RB
LEU D:311 C:329 1.0 0.006 T -148.7 -56.9 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 LEU A:311 A:329 1.0 0.006 S -142.8 -69.1 1.0 0.006 0.0 RB
RB
 7.665
8.498
 CB
N
 RB
RB
LEU D:311 C:329 1.0 0.006 H -141.8 -63.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LEU A:305 A:329 3.0 0.018 H -56.8 -49.3 3.0 0.018 0.0
LEU D:305 C:329 2.0 0.012 H -57.7 -48.7 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 K
K
HOH
 7.394
8.319
3.052
 CB
N
N
 K
K
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 LEU A:341 A:336 4.0 0.024 H -72.3 -41.4 4.0 0.024 0.0 K
K
HOH
 7.595
8.311
3.657
 N
N
N
 K
K
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.2 0.0 0.0 0.0 K
TL
K
TL
HOH
 7.395
7.395
8.319
8.319
6.672
 CB
CB
N
N
N
 K
TL
K
TL
O
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 K
TL
K
TL
HOH
 7.394
7.394
8.319
8.319
6.672
 CB
CB
N
N
N
 K
TL
K
TL
O
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 K
TL
TL
HOH
 7.395
7.395
8.318
6.672
 CB
CB
N
N
 K
TL
TL
O
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 K
TL
TL
HOH
 7.395
7.395
8.319
6.671
 CB
CB
N
N
 K
TL
TL
O
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 K
TL
TL
HOH
 7.395
7.395
8.319
6.671
 CB
CB
N
N
 K
TL
TL
O
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -72.9 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.395
8.318
6.671
 CB
N
N
 TL
TL
O
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.394
8.320
6.671
 CB
N
N
 TL
TL
O
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.395
8.319
6.671
 CB
N
N
 TL
TL
O
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.394
8.319
6.672
 CB
N
N
 TL
TL
O
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.395
8.318
6.671
 CB
N
N
 TL
TL
O
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.0 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.395
8.318
6.671
 CB
N
N
 TL
TL
O
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.1 -50.3 0.0 0.0 0.0 K
TL
TL
HOH
 7.395
7.395
8.319
6.672
 CB
CB
N
N
 K
TL
TL
O
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.1 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.394
8.319
6.672
 CB
N
N
 TL
TL
O
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -72.9 -50.3 0.0 0.0 0.0 TL
TL
HOH
 7.395
8.318
6.671
 CB
N
N
 TL
TL
O
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.1 -50.2 0.0 0.0 0.0 K
RB
K
RB
HOH
 7.394
7.394
8.318
8.318
6.670
 CB
CB
N
N
N
 K
RB
K
RB
O
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.1 -50.3 0.0 0.0 0.0 K
RB
K
RB
HOH
 7.394
7.394
8.318
8.318
6.670
 CB
CB
N
N
N
 K
RB
K
RB
O
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.1 -50.2 0.0 0.0 0.0 K
RB
K
RB
HOH
 7.395
7.395
8.319
8.319
6.670
 CB
CB
N
N
N
 K
RB
K
RB
O
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.2 -50.1 0.0 0.0 0.0 K
RB
RB
HOH
 7.395
7.395
8.318
6.670
 CB
CB
N
N
 K
RB
RB
O
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -73.1 -50.3 0.0 0.0 0.0 RB
RB
HOH
 7.395
8.319
6.670
 CB
N
N
 RB
RB
O
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:341 A:336 0.0 0.0 H -68.1 -49.0 0.0 0.0 0.0 K
K
HOH
 7.352
8.367
3.223
 CB
N
N
 K
K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 LEU A:326 A:326 1.0 0.006 H -69.1 -41.1
af-p50993-f1 1 P50993 88.81 0.0 LEU A:334 A:334 1.0 0.006 H -70.8 -42.1
af-p05023-f1 1 P05023 88.03 0.0 LEU A:336 A:336 1.0 0.006 H -72.0 -39.9