Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42489089 | . | C | A | CCDS12594.1:NM_152296.4:c.974gGt>gTt_NP_689509.1:p.325G>V | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:328 | A:328 | 2.0 | 0.027 | H | -59.4 | -48.6 | 2.0 | 0.027 | 0.0 |
NA NA PC1 HOH |
6.965 9.382 8.074 6.048 |
N N CA N |
NA NA C37 O |
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| GLY | D:328 | C:328 | 4.0 | 0.053 | T | -56.4 | -34.9 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:328 | A:328 | 1.0 | 0.013 | H | -59.4 | -51.4 | 1.0 | 0.013 | 0.0 |
NA NA PC1 EFO HOH |
6.796 9.372 8.061 9.156 6.312 |
N N CA C N |
NA NA C37 O36 O |
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| GLY | D:328 | C:328 | 4.0 | 0.053 | H | -57.3 | -29.4 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | GLY | A:333 | A:333 | 1.0 | 0.013 | T | -84.8 | -5.8 | 1.0 | 0.013 | 0.0 |
MG OBN HOH |
6.317 8.767 4.645 |
N N N |
MG O23 O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | GLY | A:333 | A:328 | 8.0 | 0.107 | H | -64.4 | -23.0 | 8.0 | 0.107 | 0.0 |
NA NA |
6.309 9.725 |
N N |
NA NA |
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| GLY | D:333 | C:328 | 7.0 | 0.093 | H | -65.0 | -23.1 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | GLY | A:333 | A:328 | 3.0 | 0.04 | H | -72.9 | -38.3 | 3.0 | 0.04 | 0.0 |
MG OBN HOH |
6.760 9.563 5.141 |
N N N |
MG O23 O |
||
| GLY | D:333 | C:328 | 3.0 | 0.04 | H | -73.5 | -37.9 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:333 | A:328 | 4.0 | 0.053 | H | -76.9 | -29.3 | 4.0 | 0.053 | 0.0 |
BUF K K |
8.471 6.332 6.997 |
N N N |
O24 K K |
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| GLY | D:333 | C:328 | 3.0 | 0.04 | H | -77.9 | -29.1 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:333 | A:328 | 3.0 | 0.04 | H | -72.9 | -16.8 | 3.0 | 0.04 | 0.0 |
MG DGX HOH |
6.592 9.072 4.926 |
N N N |
MG O23 O |
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| GLY | D:333 | C:328 | 3.0 | 0.04 | H | -72.1 | -17.2 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | GLY | A:333 | A:328 | 1.0 | 0.013 | H | -74.9 | -5.1 | 1.0 | 0.013 | 0.0 |
MG HOH |
5.874 5.785 |
N N |
MG O |
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| GLY | D:333 | C:328 | 1.0 | 0.013 | T | -76.5 | -5.9 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | T | -65.5 | -7.3 | 2.0 | 0.027 | 0.0 |
MG PCW HOH |
6.321 8.275 7.540 |
N O N |
MG O31 O |
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| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | T | -67.5 | -10.7 | 2.0 | 0.027 | 0.0 |
MG HOH |
5.971 6.555 |
N N |
MG O |
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| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | S | -94.9 | -12.0 | 2.0 | 0.027 | 0.0 |
MG HOH |
6.093 6.007 |
N N |
MG O |
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| GLY | C:328 | C:328 | 2.0 | 0.027 | S | -94.8 | -12.1 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | S | -95.3 | -11.7 | 2.0 | 0.027 | 0.0 |
MG RB BUF HOH |
6.532 6.540 8.603 3.446 |
N N N CA |
MG RB O24 O |
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| GLY | D:328 | C:328 | 1.0 | 0.013 | S | -94.9 | -10.8 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | T | -74.1 | -2.9 | 2.0 | 0.027 | 0.0 |
MG HOH |
5.825 5.732 |
N N |
MG O |
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| GLY | D:328 | C:328 | 1.0 | 0.013 | T | -72.9 | -3.0 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 4.0 | 0.053 | T | -74.7 | -16.4 | 4.0 | 0.053 | 0.0 |
MG DGX HOH |
6.095 9.533 6.166 |
N N N |
MG O23 O |
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| GLY | D:328 | C:328 | 2.0 | 0.027 | T | -74.3 | -16.1 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 1.0 | 0.013 | T | -79.8 | -4.8 | 1.0 | 0.013 | 0.0 |
MG F9R HOH |
5.955 9.500 5.630 |
N N N |
MG O23 O |
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| GLY | D:328 | C:328 | 2.0 | 0.027 | T | -79.7 | -5.0 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | S | -96.5 | -11.9 | 2.0 | 0.027 | 0.0 |
MG HOH |
6.165 6.142 |
N N |
MG O |
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| GLY | D:328 | C:328 | 1.0 | 0.013 | S | -96.2 | -12.0 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 1.0 | 0.013 | T | -81.0 | -13.7 | 1.0 | 0.013 | 0.0 |
MG HOH |
6.043 6.002 |
N N |
MG O |
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| GLY | D:328 | C:328 | 1.0 | 0.013 | T | -78.6 | -12.8 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:328 | A:328 | 2.0 | 0.027 | S | -91.4 | -13.6 | 2.0 | 0.027 | 0.0 |
MG BUF HOH |
5.949 8.629 5.779 |
N N N |
MG O24 O |
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| GLY | D:328 | C:328 | 1.0 | 0.013 | S | -87.9 | -13.4 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | GLY | A:310 | A:328 | 2.0 | 0.027 | S | -102.1 | 99.3 | 2.0 | 0.027 | 0.0 |
RB RB |
6.342 6.869 |
O N |
RB RB |
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| GLY | D:310 | C:328 | 3.0 | 0.04 | T | -114.1 | 62.8 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | GLY | A:310 | A:328 | 3.0 | 0.04 | S | -68.8 | 60.8 | 3.0 | 0.04 | 0.0 |
RB RB |
6.848 6.597 |
O N |
RB RB |
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| GLY | D:310 | C:328 | 2.0 | 0.027 | H | -71.8 | 56.1 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLY | A:304 | A:328 | 5.0 | 0.067 | S | -98.2 | -11.1 | 5.0 | 0.067 | 0.0 | ||||||
| GLY | D:304 | C:328 | 5.0 | 0.067 | S | -97.3 | -11.1 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.1 | 4.0 | 0.053 | 0.0 |
K K HOH |
6.870 6.812 2.793 |
N N N |
K K O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | GLY | A:340 | A:335 | 5.0 | 0.067 | T | -92.7 | -3.8 | 5.0 | 0.067 | 0.0 |
K K HOH |
6.993 6.810 2.965 |
N N N |
K K O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.0 | 4.0 | 0.053 | 0.0 |
K TL K TL HOH |
6.870 6.870 6.813 6.813 6.087 |
N N N N N |
K TL K TL O |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.1 | 4.0 | 0.053 | 0.0 |
K TL K TL HOH |
6.870 6.870 6.813 6.813 6.086 |
N N N N N |
K TL K TL O |
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| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.0 | 4.0 | 0.053 | 0.0 |
K TL TL HOH |
6.870 6.870 6.812 6.087 |
N N N N |
K TL TL O |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.1 | 4.0 | 0.053 | 0.0 |
K TL TL HOH |
6.870 6.870 6.812 6.085 |
N N N N |
K TL TL O |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.2 | 5.0 | 4.0 | 0.053 | 0.0 |
K TL TL HOH |
6.870 6.870 6.812 6.086 |
N N N N |
K TL TL O |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.2 | 4.9 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.870 6.812 6.087 |
N N N |
TL TL O |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.0 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.869 6.813 6.086 |
N N N |
TL TL O |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.0 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.870 6.812 6.086 |
N N N |
TL TL O |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.1 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.870 6.813 6.087 |
N N N |
TL TL O |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.1 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.869 6.811 6.086 |
N N N |
TL TL O |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.0 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.869 6.812 6.086 |
N N N |
TL TL O |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.4 | 5.1 | 4.0 | 0.053 | 0.0 |
K TL TL HOH |
6.869 6.869 6.812 6.086 |
N N N N |
K TL TL O |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.2 | 5.2 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.869 6.813 6.085 |
N N N |
TL TL O |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.2 | 4.9 | 4.0 | 0.053 | 0.0 |
TL TL HOH |
6.870 6.812 6.086 |
N N N |
TL TL O |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.3 | 5.1 | 4.0 | 0.053 | 0.0 |
K RB K RB HOH |
6.869 6.869 6.812 6.812 6.085 |
N N N N N |
K RB K RB O |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.4 | 5.0 | 4.0 | 0.053 | 0.0 |
K RB K RB HOH |
6.869 6.869 6.813 6.813 6.085 |
N N N N N |
K RB K RB O |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.4 | 5.1 | 4.0 | 0.053 | 0.0 |
K RB K RB HOH |
6.868 6.868 6.812 6.812 6.084 |
N N N N N |
K RB K RB O |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.4 | 5.1 | 4.0 | 0.053 | 0.0 |
K RB RB HOH |
6.870 6.870 6.812 6.085 |
N N N N |
K RB RB O |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 4.0 | 0.053 | T | -102.4 | 5.2 | 4.0 | 0.053 | 0.0 |
RB RB HOH |
6.869 6.813 6.085 |
N N N |
RB RB O |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:340 | A:335 | 3.0 | 0.04 | T | -99.9 | 0.0 | 3.0 | 0.04 | 0.0 |
K K HOH |
6.847 6.903 2.881 |
N N N |
K K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | GLY | A:325 | A:325 | 1.0 | 0.013 | T | -75.1 | -18.3 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | GLY | A:333 | A:333 | 2.0 | 0.027 | T | -76.4 | -14.9 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | GLY | A:335 | A:335 | 0.0 | 0.0 | T | -76.9 | -13.7 | |