Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489117 . C A CCDS12594.1:NM_152296.4:c.946Ggc>Tgc_NP_689509.1:p.316G>C Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLY A:319 A:319 3.0 0.04 H -73.9 -36.6 3.0 0.04 0.0 NA
NA
HOH
 7.104
8.376
8.919
 O
O
O
 NA
NA
O
GLY D:319 C:319 1.0 0.013 H -54.9 -50.6 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLY A:319 A:319 3.0 0.04 H -63.9 -40.1 3.0 0.04 0.0 NA
NA
HOH
 6.886
8.312
8.787
 O
O
O
 NA
NA
O
GLY D:319 C:319 1.0 0.013 H -63.9 -49.1 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 GLY A:324 A:324 28.0 0.373 H -53.7 -46.5 28.0 0.373 0.0 OBN
HOH
 3.801
8.804
 O
O
 C17
O
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 GLY A:324 A:319 0.0 0.0 H -54.3 -56.3 0.0 0.0 0.0 NA
NA
 7.018
7.437
 O
O
 NA
NA
GLY D:324 C:319 0.0 0.0 H -54.5 -54.3 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 GLY A:324 A:319 25.0 0.333 H -50.7 -59.1 25.0 0.333 0.0 OBN
HOH
 3.724
8.398
 O
O
 C22
O
GLY D:324 C:319 26.0 0.347 H -51.7 -58.8 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLY A:324 A:319 20.0 0.267 H -52.4 -48.9 20.0 0.267 0.0 BUF
K
 3.407
7.358
 O
O
 C17
K
GLY D:324 C:319 21.0 0.28 H -51.4 -49.2 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLY A:324 A:319 26.0 0.347 H -57.8 -52.8 26.0 0.347 0.0 DGX
HOH
 3.141
8.312
 CA
O
 O12
O
GLY D:324 C:319 26.0 0.347 H -58.2 -52.7 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 GLY A:324 A:319 23.0 0.307 H -62.7 -40.1 23.0 0.307 0.0 JEO
HOH
 4.219
7.854
 CA
O
 CAH
O
GLY D:324 C:319 16.0 0.213 H -63.0 -38.8 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 17.0 0.227 H -64.7 -34.8 17.0 0.227 0.0 MG
HOH
 9.283
6.979
 O
O
 MG
O
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 24.0 0.32 H -64.1 -38.2 24.0 0.32 0.0 MG
H0C
HOH
 9.816
3.534
6.702
 O
O
O
 MG
C17
O
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 22.0 0.293 H -64.1 -40.7 22.0 0.293 0.0 H0C
HOH
 3.817
6.676
 O
O
 C17
O
GLY C:319 C:319 25.0 0.333 H -63.1 -39.7 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 21.0 0.28 H -63.3 -41.4 21.0 0.28 0.0 MG
BUF
HOH
 8.219
3.632
6.538
 O
O
O
 MG
C21
O
GLY D:319 C:319 23.0 0.307 H -63.0 -40.9 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 18.0 0.24 H -62.5 -38.9 18.0 0.24 0.0 HOH
 8.088
 O
 O
GLY D:319 C:319 20.0 0.267 H -62.7 -38.5 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 23.0 0.307 H -63.7 -44.4 23.0 0.307 0.0 MG
DGX
HOH
 9.846
3.176
7.810
 O
CA
O
 MG
O12
O
GLY D:319 C:319 16.0 0.213 H -63.5 -43.9 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 21.0 0.28 H -60.7 -44.6 21.0 0.28 0.0 MG
F9R
HOH
 9.718
3.204
7.709
 O
O
O
 MG
C22
O
GLY D:319 C:319 21.0 0.28 H -60.5 -43.4 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 21.0 0.28 H -63.2 -41.2 21.0 0.28 0.0 MG
OBN
HOH
 9.901
3.318
6.872
 O
O
O
 MG
C22
O
GLY D:319 C:319 22.0 0.293 H -63.3 -41.0 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 21.0 0.28 H -67.1 -48.7 21.0 0.28 0.0 MG
E4R
HOH
 9.904
2.937
8.043
 O
CA
O
 MG
O2
O
GLY D:319 C:319 23.0 0.307 H -67.1 -47.9 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:319 A:319 20.0 0.267 H -64.3 -40.2 20.0 0.267 0.0 MG
BUF
HOH
 9.909
3.609
7.735
 O
O
O
 MG
C21
O
GLY D:319 C:319 22.0 0.293 H -64.3 -39.7 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 GLY A:301 A:319 0.0 0.0 H -87.0 -67.6 0.0 0.0 0.0 RB
 7.150
 O
 RB
GLY D:301 C:319 2.0 0.027 H -74.0 -73.9 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 GLY A:301 A:319 0.0 0.0 H -74.0 -65.0 0.0 0.0 0.0 RB
 7.610
 O
 RB
GLY D:301 C:319 1.0 0.013 H -94.3 -70.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLY A:295 A:319 27.0 0.36 T -59.0 -58.7 27.0 0.36 0.0 OBN
 3.827
 O
 O23
GLY D:295 C:319 27.0 0.36 T -57.8 -58.9 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 K
HOH
 7.350
3.998
 O
N
 K
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 GLY A:331 A:326 36.0 0.48 H -47.9 -62.4 36.0 0.48 0.0 K
OBN
HOH
 9.561
2.659
9.883
 O
O
CA
 K
C22
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 K
TL
 7.350
7.350
 O
O
 K
TL
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 K
TL
 7.350
7.350
 O
O
 K
TL
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.2 0.0 0.0 0.0 TL
 7.350
 O
 TL
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 TL
 7.350
 O
 TL
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.2 0.0 0.0 0.0 TL
 7.351
 O
 TL
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 TL
 7.350
 O
 TL
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 TL
 7.351
 O
 TL
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.2 0.0 0.0 0.0 TL
 7.350
 O
 TL
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 TL
 7.350
 O
 TL
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 TL
 7.350
 O
 TL
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 TL
 7.351
 O
 TL
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 TL
 7.351
 O
 TL
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.7 -44.2 0.0 0.0 0.0 TL
 7.351
 O
 TL
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 TL
 7.350
 O
 TL
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.4 0.0 0.0 0.0 K
RB
 7.352
7.352
 O
O
 K
RB
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.2 0.0 0.0 0.0 K
RB
 7.351
7.351
 O
O
 K
RB
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 K
RB
 7.348
7.348
 O
O
 K
RB
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.3 0.0 0.0 0.0 RB
 7.351
 O
 RB
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -60.6 -44.2 0.0 0.0 0.0 RB
 7.350
 O
 RB
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:331 A:326 0.0 0.0 H -49.9 -55.5 0.0 0.0 0.0 K
HOH
 7.291
3.938
 O
N
 K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 GLY A:316 A:316 5.0 0.067 H -57.6 -42.4
af-p50993-f1 1 P50993 88.81 0.0 GLY A:324 A:324 4.0 0.053 H -57.3 -42.3
af-p05023-f1 1 P05023 88.03 0.0 GLY A:326 A:326 8.0 0.107 H -57.7 -42.5