Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42489120 | . | T | A | CCDS12594.1:NM_152296.4:c.943Atc>Ttc_NP_689509.1:p.315I>F | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | ILE | A:318 | A:318 | 15.0 | 0.086 | H | -63.2 | -29.1 | 15.0 | 0.086 | 0.0 |
NA |
8.988 |
O |
NA |
||
| ILE | D:318 | C:318 | 26.0 | 0.149 | H | -46.4 | -47.4 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | ILE | A:318 | A:318 | 14.0 | 0.08 | H | -67.6 | -32.1 | 14.0 | 0.08 | 0.0 |
NA |
8.633 |
O |
NA |
||
| ILE | D:318 | C:318 | 22.0 | 0.126 | H | -52.3 | -40.8 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | ILE | A:323 | A:323 | 16.0 | 0.091 | H | -60.4 | -44.7 | 16.0 | 0.091 | 0.0 |
OBN |
5.901 |
C |
C12 |
||
| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | ILE | A:323 | A:318 | 6.0 | 0.034 | H | -54.1 | -43.9 | 6.0 | 0.034 | 0.0 |
NA NA |
8.321 9.964 |
O O |
NA NA |
||
| ILE | D:323 | C:318 | 6.0 | 0.034 | H | -53.2 | -44.8 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | ILE | A:323 | A:318 | 13.0 | 0.074 | H | -57.7 | -44.2 | 13.0 | 0.074 | 0.0 |
OBN |
5.783 |
C |
C12 |
||
| ILE | D:323 | C:318 | 11.0 | 0.063 | H | -59.1 | -43.2 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | ILE | A:323 | A:318 | 8.0 | 0.046 | H | -61.3 | -48.6 | 8.0 | 0.046 | 0.0 |
BUF K |
5.662 9.386 |
O O |
C21 K |
||
| ILE | D:323 | C:318 | 7.0 | 0.04 | H | -61.2 | -49.4 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | ILE | A:323 | A:318 | 13.0 | 0.074 | H | -55.3 | -41.9 | 13.0 | 0.074 | 0.0 |
DGX |
4.704 |
C |
O12 |
||
| ILE | D:323 | C:318 | 12.0 | 0.069 | H | -55.1 | -41.8 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | ILE | A:323 | A:318 | 11.0 | 0.063 | H | -65.1 | -43.3 | 11.0 | 0.063 | 0.0 |
JEO |
6.451 |
C |
CAH |
||
| ILE | D:323 | C:318 | 7.0 | 0.04 | H | -63.6 | -45.1 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 9.0 | 0.051 | H | -65.1 | -43.3 | 9.0 | 0.051 | 0.0 |
HOH |
9.460 |
O |
O |
||
| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 14.0 | 0.08 | H | -64.9 | -41.1 | 14.0 | 0.08 | 0.0 |
H0C HOH |
5.577 8.697 |
O O |
C17 O |
||
| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 11.0 | 0.063 | H | -64.9 | -41.0 | 11.0 | 0.063 | 0.0 |
H0C HOH |
5.888 8.639 |
O O |
C17 O |
||
| ILE | C:318 | C:318 | 12.0 | 0.069 | H | -65.1 | -42.5 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 10.0 | 0.057 | H | -65.2 | -40.2 | 10.0 | 0.057 | 0.0 |
BUF HOH |
5.770 8.687 |
O O |
C21 O |
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| ILE | D:318 | C:318 | 7.0 | 0.04 | H | -64.9 | -40.9 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 11.0 | 0.063 | H | -66.2 | -43.5 | 11.0 | 0.063 | 0.0 | ||||||
| ILE | D:318 | C:318 | 13.0 | 0.074 | H | -64.4 | -43.7 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 16.0 | 0.091 | H | -61.3 | -42.6 | 16.0 | 0.091 | 0.0 |
DGX |
4.811 |
C |
O12 |
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| ILE | D:318 | C:318 | 9.0 | 0.051 | H | -61.9 | -42.3 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 8.0 | 0.046 | H | -60.9 | -42.6 | 8.0 | 0.046 | 0.0 |
F9R |
5.163 |
O |
C22 |
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| ILE | D:318 | C:318 | 6.0 | 0.034 | H | -60.5 | -42.9 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 13.0 | 0.074 | H | -65.4 | -39.7 | 13.0 | 0.074 | 0.0 |
OBN HOH |
5.394 8.751 |
O O |
C22 O |
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| ILE | D:318 | C:318 | 12.0 | 0.069 | H | -64.5 | -40.5 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 11.0 | 0.063 | H | -59.8 | -36.0 | 11.0 | 0.063 | 0.0 |
E4R |
4.790 |
O |
O2 |
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| ILE | D:318 | C:318 | 9.0 | 0.051 | H | -59.0 | -37.1 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:318 | A:318 | 11.0 | 0.063 | H | -65.1 | -40.8 | 11.0 | 0.063 | 0.0 |
BUF |
5.739 |
O |
C21 |
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| ILE | D:318 | C:318 | 8.0 | 0.046 | H | -65.1 | -40.5 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | ILE | A:300 | A:318 | 2.0 | 0.011 | H | -59.0 | -6.4 | 2.0 | 0.011 | 0.0 |
RB |
9.556 |
O |
RB |
||
| ILE | D:300 | C:318 | 2.0 | 0.011 | H | -55.2 | -16.3 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | ILE | A:300 | A:318 | 1.0 | 0.006 | H | -36.8 | -34.1 | 1.0 | 0.006 | 0.0 |
RB |
9.340 |
O |
RB |
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| ILE | D:300 | C:318 | 1.0 | 0.006 | H | -53.1 | -4.9 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ILE | A:294 | A:318 | 33.0 | 0.189 | T | -58.3 | -26.8 | 33.0 | 0.189 | 0.0 |
OBN |
6.235 |
CG2 |
O11 |
||
| ILE | D:294 | C:318 | 33.0 | 0.189 | T | -58.7 | -27.2 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
K HOH |
9.207 4.027 |
O CB |
K O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | ILE | A:330 | A:325 | 20.0 | 0.114 | H | -59.4 | -34.1 | 20.0 | 0.114 | 0.0 |
OBN |
5.321 |
O |
O23 |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.8 | -46.4 | 4.0 | 0.023 | 0.0 |
K TL |
9.207 9.207 |
O O |
K TL |
||
| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.4 | 4.0 | 0.023 | 0.0 |
K TL |
9.208 9.208 |
O O |
K TL |
||
| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.207 |
O |
TL |
||
| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.207 |
O |
TL |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.208 |
O |
TL |
||
| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.8 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.207 |
O |
TL |
||
| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.8 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.207 |
O |
TL |
||
| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 3.0 | 0.017 | H | -53.7 | -46.6 | 3.0 | 0.017 | 0.0 |
TL |
9.207 |
O |
TL |
||
| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 3.0 | 0.017 | H | -53.8 | -46.4 | 3.0 | 0.017 | 0.0 |
TL |
9.207 |
O |
TL |
||
| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.207 |
O |
TL |
||
| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.6 | -46.4 | 4.0 | 0.023 | 0.0 |
TL |
9.208 |
O |
TL |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.4 | 4.0 | 0.023 | 0.0 |
TL |
9.206 |
O |
TL |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.8 | -46.4 | 4.0 | 0.023 | 0.0 |
TL |
9.206 |
O |
TL |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.8 | -46.5 | 4.0 | 0.023 | 0.0 |
TL |
9.206 |
O |
TL |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
K RB |
9.207 9.207 |
O O |
K RB |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
K RB |
9.207 9.207 |
O O |
K RB |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
K RB |
9.206 9.206 |
O O |
K RB |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.7 | -46.5 | 4.0 | 0.023 | 0.0 |
RB |
9.207 |
O |
RB |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 4.0 | 0.023 | H | -53.8 | -46.4 | 4.0 | 0.023 | 0.0 |
RB |
9.205 |
O |
RB |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:330 | A:325 | 3.0 | 0.017 | H | -54.1 | -49.2 | 3.0 | 0.017 | 0.0 |
K HOH |
9.198 4.053 |
O CG2 |
K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | ILE | A:315 | A:315 | 5.0 | 0.029 | H | -61.1 | -50.5 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | ILE | A:323 | A:323 | 5.0 | 0.029 | H | -60.8 | -51.2 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | ILE | A:325 | A:325 | 5.0 | 0.029 | H | -64.2 | -49.7 | |