Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489234 . C A CCDS12594.1:NM_152296.4:c.829Gag>Tag_NP_689509.1:p.277E>* Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLU A:280 A:280 30.0 0.158 H -67.9 -46.8 30.0 0.158 0.0 PC1
HOH
 6.486
6.537
 O
C
 O32
O
GLU D:280 C:280 36.0 0.189 H -62.8 -46.2 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLU A:280 A:280 30.0 0.158 H -58.6 -51.8 30.0 0.158 0.0 PC1
EFO
 6.597
7.584
 O
N
 O32
C51
GLU D:280 C:280 35.0 0.184 H -64.0 -48.0 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 GLU A:285 A:285 9.0 0.047 H -58.5 -39.6 9.0 0.047 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 GLU A:285 A:280 28.0 0.147 H -69.7 -30.4 28.0 0.147 0.0
GLU D:285 C:280 30.0 0.158 H -69.8 -30.0 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 GLU A:285 A:280 5.0 0.026 H -53.8 -39.4 5.0 0.026 0.0 17F
17F
 8.301
7.466
 OE1
O
 N1
O5
GLU D:285 C:280 4.0 0.021 H -54.4 -39.0 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLU A:285 A:280 5.0 0.026 H -66.1 -46.6 5.0 0.026 0.0
GLU D:285 C:280 5.0 0.026 H -66.0 -47.2 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLU A:285 A:280 4.0 0.021 H -58.0 -40.7 4.0 0.021 0.0 17F
17F
 7.418
7.811
 OE1
O
 O4
O4
GLU D:285 C:280 5.0 0.026 H -57.8 -41.1 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 GLU A:285 A:280 5.0 0.026 H -70.4 -33.5 5.0 0.026 0.0 PCW
PCW
 7.889
7.426
 OE1
OE2
 C8
C6
GLU D:285 C:280 4.0 0.021 H -69.1 -34.6 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -68.3 -40.7 5.0 0.026 0.0 PCW
 9.787
 O
 O2P
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -67.6 -39.9 5.0 0.026 0.0 PCW
 8.667
 OE1
 C7
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -70.7 -39.1 5.0 0.026 0.0 PCW
 7.678
 OE1
 C7
GLU C:280 C:280 12.0 0.063 H -71.4 -37.8 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -71.0 -39.7 5.0 0.026 0.0 PCW
 7.291
 OE1
 C8
GLU D:280 C:280 12.0 0.063 H -70.8 -39.5 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 2.0 0.011 H -71.1 -33.7 2.0 0.011 0.0 PCW
 7.209
 OE1
 C8
GLU D:280 C:280 6.0 0.032 H -70.9 -31.4 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -66.1 -36.9 5.0 0.026 0.0 PCW
PCW
 7.366
7.579
 OE1
OE2
 C8
C6
GLU D:280 C:280 6.0 0.032 H -66.1 -35.7 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 4.0 0.021 H -65.0 -37.1 4.0 0.021 0.0 PCW
PCW
 7.262
7.043
 OE1
N
 C8
C6
GLU D:280 C:280 7.0 0.037 H -64.5 -36.9 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 4.0 0.021 H -70.3 -41.0 4.0 0.021 0.0 PCW
PCW
 7.333
9.170
 OE1
O
 C6
O2P
GLU D:280 C:280 11.0 0.058 H -70.2 -39.0 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -67.6 -35.9 5.0 0.026 0.0 PCW
 6.973
 OE1
 C8
GLU D:280 C:280 8.0 0.042 H -66.9 -35.6 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLU A:280 A:280 5.0 0.026 H -69.3 -41.3 5.0 0.026 0.0 PCW
PCW
 6.584
7.100
 OE1
OE2
 C8
C6
GLU D:280 C:280 10.0 0.053 H -69.4 -40.2 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 GLU A:262 A:280 13.0 0.068 H -89.2 -25.1 13.0 0.068 0.0
GLU D:262 C:280 13.0 0.068 H -85.1 -20.5 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 GLU A:262 A:280 5.0 0.026 H -111.6 -52.5 5.0 0.026 0.0
GLU D:262 C:280 5.0 0.026 H -117.1 -35.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLU A:256 A:280 3.0 0.016 H -56.4 -46.4 3.0 0.016 0.0
GLU D:256 C:280 4.0 0.021 H -57.5 -46.4 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 GLU A:292 A:287 3.0 0.016 H -58.7 -44.6 3.0 0.016 0.0 HOH
 2.823
 O
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 GLU A:292 A:287 2.0 0.011 H -66.3 -36.2 2.0 0.011 0.0 HOH
 2.632
 O
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.8 -44.5 3.0 0.016 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.6 -44.6 3.0 0.016 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.6 -44.7 3.0 0.016 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.5 3.0 0.016 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.6 3.0 0.016 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.6 3.0 0.016 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.6 3.0 0.016 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.8 -44.5 3.0 0.016 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.5 3.0 0.016 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.8 -44.6 3.0 0.016 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.6 3.0 0.016 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.8 -44.4 3.0 0.016 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.8 -44.6 3.0 0.016 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.5 3.0 0.016 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.6 -44.6 3.0 0.016 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.6 -44.6 3.0 0.016 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.6 -44.6 3.0 0.016 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.7 -44.5 3.0 0.016 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.6 -44.6 3.0 0.016 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLU A:292 A:287 3.0 0.016 H -58.3 -45.1 3.0 0.016 0.0 HOH
 2.919
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 GLU A:277 A:277 2.0 0.011 H -66.4 -41.6
af-p50993-f1 1 P50993 88.81 0.0 GLU A:285 A:285 3.0 0.016 H -67.0 -42.1
af-p05023-f1 1 P05023 88.03 0.0 GLU A:287 A:287 2.0 0.011 H -69.7 -39.5