Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489243 . T A CCDS12594.1:NM_152296.4:c.820Atc>Ttc_NP_689509.1:p.274I>F Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ILE A:277 A:277 8.0 0.046 H -53.6 -42.5 8.0 0.046 0.0 HOH
 5.646
 O
 O
ILE D:277 C:277 7.0 0.04 H -64.2 -45.0 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ILE A:277 A:277 10.0 0.057 H -59.3 -37.5 10.0 0.057 0.0 EFO
HOH
 6.618
9.998
 O
N
 C3
O
ILE D:277 C:277 7.0 0.04 H -69.0 -42.2 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 ILE A:282 A:282 5.0 0.029 H -61.4 -45.1 5.0 0.029 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 ILE A:282 A:277 7.0 0.04 H -56.2 -43.8 7.0 0.04 0.0
ILE D:282 C:277 9.0 0.051 H -56.7 -43.7 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 ILE A:282 A:277 4.0 0.023 H -62.0 -41.5 4.0 0.023 0.0
ILE D:282 C:277 4.0 0.023 H -64.4 -41.8 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ILE A:282 A:277 6.0 0.034 H -71.8 -32.5 6.0 0.034 0.0
ILE D:282 C:277 5.0 0.029 H -73.3 -31.2 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ILE A:282 A:277 3.0 0.017 H -60.9 -41.4 3.0 0.017 0.0
ILE D:282 C:277 5.0 0.029 H -63.7 -41.4 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 ILE A:282 A:277 5.0 0.029 H -67.4 -39.4 5.0 0.029 0.0
ILE D:282 C:277 3.0 0.017 H -67.1 -40.3 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 1.0 0.006 H -75.4 -38.4 1.0 0.006 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 0.0 0.0 H -66.9 -39.7 0.0 0.0 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 1.0 0.006 H -62.6 -39.2 1.0 0.006 0.0
ILE C:277 C:277 1.0 0.006 H -64.7 -38.6 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 0.0 0.0 H -62.4 -39.8 0.0 0.0 0.0
ILE D:277 C:277 3.0 0.017 H -63.5 -39.4 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 3.0 0.017 H -63.7 -41.2 3.0 0.017 0.0
ILE D:277 C:277 3.0 0.017 H -64.8 -40.9 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 1.0 0.006 H -60.9 -36.9 1.0 0.006 0.0
ILE D:277 C:277 2.0 0.011 H -62.5 -37.2 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 1.0 0.006 H -63.7 -41.4 1.0 0.006 0.0
ILE D:277 C:277 1.0 0.006 H -64.4 -41.3 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 0.0 0.0 H -61.6 -38.2 0.0 0.0 0.0
ILE D:277 C:277 3.0 0.017 H -63.4 -38.3 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 1.0 0.006 H -63.8 -42.4 1.0 0.006 0.0
ILE D:277 C:277 1.0 0.006 H -64.3 -41.0 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ILE A:277 A:277 0.0 0.0 H -62.6 -37.7 0.0 0.0 0.0
ILE D:277 C:277 0.0 0.0 H -63.1 -38.2 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 ILE A:259 A:277 1.0 0.006 H -48.7 -39.7 1.0 0.006 0.0
ILE D:259 C:277 2.0 0.011 H -58.3 -55.3 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 ILE A:259 A:277 1.0 0.006 S -80.2 -54.3 1.0 0.006 0.0
ILE D:259 C:277 1.0 0.006 S -81.5 -58.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ILE A:253 A:277 10.0 0.057 H -51.3 -40.9 10.0 0.057 0.0
ILE D:253 C:277 8.0 0.046 H -47.9 -43.7 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0 HOH
 6.365
 CG2
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 ILE A:289 A:284 1.0 0.006 H -50.4 -45.6 1.0 0.006 0.0 HOH
 5.986
 CD1
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.0 0.0 0.0 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.3 -42.1 0.0 0.0 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.3 -42.0 0.0 0.0 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.3 -42.1 0.0 0.0 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.3 -42.1 0.0 0.0 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.0 0.0 0.0 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.5 -42.0 0.0 0.0 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.3 -42.2 0.0 0.0 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -41.9 0.0 0.0 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.0 0.0 0.0 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.5 -42.1 0.0 0.0 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.5 -42.1 0.0 0.0 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.1 0.0 0.0 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -60.4 -42.2 0.0 0.0 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ILE A:289 A:284 0.0 0.0 H -58.1 -44.5 0.0 0.0 0.0 HOH
 6.457
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 ILE A:274 A:274 0.0 0.0 H -63.7 -38.1
af-p50993-f1 1 P50993 88.81 0.0 ILE A:282 A:282 0.0 0.0 H -62.6 -38.2
af-p05023-f1 1 P05023 88.03 0.0 ILE A:284 A:284 0.0 0.0 H -64.2 -38.4