Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489517 . G A CCDS12594.1:NM_152296.4:c.665aCt>aTt_NP_689509.1:p.222T>I Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:225 A:225 63.0 0.45 -106.9 -34.1 63.0 0.45 0.0
THR D:225 C:225 68.0 0.486 -121.0 -25.5 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 THR A:225 A:225 64.0 0.457 -124.7 -27.3 64.0 0.457 0.0
THR D:225 C:225 65.0 0.464 -126.3 -18.7 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 THR A:230 A:230 65.0 0.464 -108.4 -65.6 65.0 0.464 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 THR A:230 A:225 60.0 0.429 -121.7 -32.1 60.0 0.429 0.0
THR D:230 C:225 60.0 0.429 -122.0 -31.7 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 THR A:230 A:225 67.0 0.479 -116.8 -62.1 67.0 0.479 0.0
THR D:230 C:225 68.0 0.486 -116.6 -62.1 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:230 A:225 53.0 0.379 -116.3 -68.8 53.0 0.379 0.0
THR D:230 C:225 54.0 0.386 -116.6 -68.6 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 THR A:230 A:225 67.0 0.479 -114.5 -66.0 67.0 0.479 0.0
THR D:230 C:225 66.0 0.471 -114.6 -66.1 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 THR A:230 A:225 75.0 0.536 -115.2 -59.6 75.0 0.536 0.0
THR D:230 C:225 70.0 0.5 -114.3 -60.1 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 69.0 0.493 -114.8 -55.8 69.0 0.493 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 69.0 0.493 -113.4 -56.1 69.0 0.493 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 72.0 0.514 -114.3 -42.4 72.0 0.514 0.0
THR C:225 C:225 74.0 0.529 -113.3 -38.5 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 72.0 0.514 -114.0 -43.1 72.0 0.514 0.0
THR D:225 C:225 74.0 0.529 -113.4 -39.5 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 68.0 0.486 -114.9 -53.9 68.0 0.486 0.0
THR D:225 C:225 68.0 0.486 -114.4 -55.2 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 65.0 0.464 -107.2 -48.3 65.0 0.464 0.0
THR D:225 C:225 68.0 0.486 -105.6 -46.8 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 66.0 0.471 -116.0 -53.8 66.0 0.471 0.0
THR D:225 C:225 68.0 0.486 -117.0 -52.7 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 73.0 0.521 -114.7 -41.9 73.0 0.521 0.0
THR D:225 C:225 76.0 0.543 -114.1 -37.6 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 71.0 0.507 -115.1 -57.8 71.0 0.507 0.0
THR D:225 C:225 69.0 0.493 -114.1 -57.6 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 THR A:225 A:225 73.0 0.521 -114.5 -40.6 73.0 0.521 0.0
THR D:225 C:225 74.0 0.529 -114.3 -40.6 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 THR A:207 A:225 62.0 0.443 -172.5 171.1 62.0 0.443 0.0
THR D:207 C:225 64.0 0.457 -172.9 170.9 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 THR A:207 A:225 61.0 0.436 -125.4 -23.4 61.0 0.436 0.0
THR D:207 C:225 62.0 0.443 -129.2 -20.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:201 A:225 70.0 0.5 -105.6 -77.4 70.0 0.5 0.0
THR D:201 C:225 69.0 0.493 -108.8 -79.4 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 SER A:237 A:232 55.0 0.478 -130.9 1.1 55.0 0.478 0.0 HOH
 2.765
 OG
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 SER A:237 A:232 62.0 0.539 -130.2 -11.3 62.0 0.539 0.0 HOH
 4.445
 O
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.8 1.1 55.0 0.478 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.1 55.0 0.478 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -131.0 1.3 55.0 0.478 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.8 1.1 55.0 0.478 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.8 1.1 55.0 0.478 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 54.0 0.47 -130.8 1.1 54.0 0.47 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 54.0 0.47 -130.9 1.2 54.0 0.47 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.1 55.0 0.478 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.8 1.1 55.0 0.478 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.1 55.0 0.478 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.1 55.0 0.478 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.9 1.2 55.0 0.478 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 55.0 0.478 -130.8 1.1 55.0 0.478 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:237 A:232 57.0 0.496 -139.4 2.4 57.0 0.496 0.0 HOH
 2.791
 OG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 THR A:222 A:222 66.0 0.471 -110.4 -16.3
af-p50993-f1 1 P50993 88.81 0.0 THR A:230 A:230 60.0 0.429 -119.8 -21.0
af-p05023-f1 1 P05023 88.03 0.0 THR A:232 A:232 67.0 0.479 -125.9 -19.9