Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42490329 . G A CCDS12594.1:NM_152296.4:c.410tCc>tTc_NP_689509.1:p.137S>F Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 SER A:140 A:140 8.0 0.07 H -52.3 -40.1 8.0 0.07 0.0 PC1
 6.975
 N
 C22
SER D:140 C:140 10.0 0.087 H -59.5 -37.9 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 SER A:140 A:140 8.0 0.07 H -52.6 -44.5 8.0 0.07 0.0 PC1
EFO
 6.961
7.314
 N
CB
 C22
C1D
SER D:140 C:140 9.0 0.078 H -59.9 -37.4 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 SER A:145 A:145 5.0 0.043 H -58.6 -43.8 5.0 0.043 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 SER A:145 A:140 15.0 0.13 H -55.3 -34.5 15.0 0.13 0.0
SER D:145 C:140 14.0 0.122 H -55.1 -34.5 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 SER A:145 A:140 6.0 0.052 H -59.8 -41.2 6.0 0.052 0.0
SER D:145 C:140 5.0 0.043 H -59.2 -41.2 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 SER A:145 A:140 4.0 0.035 H -63.2 -40.9 4.0 0.035 0.0
SER D:145 C:140 4.0 0.035 H -63.0 -41.5 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 SER A:145 A:140 5.0 0.043 H -56.8 -43.0 5.0 0.043 0.0
SER D:145 C:140 6.0 0.052 H -56.8 -43.2 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 SER A:145 A:140 3.0 0.026 H -66.6 -35.6 3.0 0.026 0.0 PCW
 5.530
 N
 O31
SER D:145 C:140 3.0 0.026 H -65.5 -35.0 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 1.0 0.009 H -64.2 -41.7 1.0 0.009 0.0 PCW
PCW
 5.872
9.692
 N
N
 C32
O1P
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 2.0 0.017 H -63.9 -41.5 2.0 0.017 0.0 PCW
 5.880
 N
 C32
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 3.0 0.026 H -61.6 -37.1 3.0 0.026 0.0 PCW
 7.950
 N
 C32
SER C:140 C:140 2.0 0.017 H -64.9 -35.4 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 3.0 0.026 H -61.7 -36.5 3.0 0.026 0.0 PCW
PCW
 5.491
8.760
 N
C
 O31
O31
SER D:140 C:140 3.0 0.026 H -63.3 -33.8 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 3.0 0.026 H -64.2 -33.5 3.0 0.026 0.0 PCW
 6.359
 N
 O31
SER D:140 C:140 2.0 0.017 H -63.7 -33.0 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 4.0 0.035 H -62.1 -38.4 4.0 0.035 0.0 PCW
 6.096
 N
 O31
SER D:140 C:140 5.0 0.043 H -62.5 -37.5 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 4.0 0.035 H -60.0 -42.7 4.0 0.035 0.0 PCW
PCW
 5.556
8.471
 N
C
 O31
O31
SER D:140 C:140 4.0 0.035 H -59.8 -41.5 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 3.0 0.026 H -61.7 -38.1 3.0 0.026 0.0 PCW
PCW
 6.148
9.206
 N
O
 O31
O4P
SER D:140 C:140 4.0 0.035 H -63.6 -35.2 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 4.0 0.035 H -62.4 -36.3 4.0 0.035 0.0 PCW
PCW
 5.622
9.818
 N
O
 O31
O2P
SER D:140 C:140 3.0 0.026 H -62.3 -36.6 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 SER A:140 A:140 2.0 0.017 H -62.2 -35.6 2.0 0.017 0.0 PCW
PCW
 5.453
8.808
 N
C
 O31
O31
SER D:140 C:140 2.0 0.017 H -62.5 -34.3 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 SER A:122 A:140 24.0 0.209 T -90.9 26.4 24.0 0.209 0.0
SER D:122 C:140 16.0 0.139 T -91.2 26.7 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 SER A:122 A:140 12.0 0.104 T -96.2 47.8 12.0 0.104 0.0
SER D:122 C:140 10.0 0.087 H -102.6 9.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 SER A:116 A:140 25.0 0.217 H -97.0 -27.1 25.0 0.217 0.0
SER D:116 C:140 26.0 0.226 H -97.5 -27.3 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0 HOH
 5.307
 OG
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 SER A:152 A:147 19.0 0.165 H -93.0 -16.3 19.0 0.165 0.0 HOH
 5.165
 CB
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.0 -31.9 18.0 0.157 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.0 -31.9 18.0 0.157 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.2 -31.9 18.0 0.157 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.0 -31.9 18.0 0.157 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.8 18.0 0.157 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.0 -31.9 18.0 0.157 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.2 -31.9 18.0 0.157 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.8 18.0 0.157 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.0 -31.9 18.0 0.157 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.8 18.0 0.157 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.8 18.0 0.157 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.2 -31.8 18.0 0.157 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.2 -31.8 18.0 0.157 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 18.0 0.157 H -72.1 -31.9 18.0 0.157 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 SER A:152 A:147 16.0 0.139 H -70.5 -33.6 16.0 0.139 0.0 HOH
 4.928
 OG
 O
1bg5 1 P08515 100.0 6e-07 X-RAY
 1999-01-13 SER A:227 A:227 87.0 0.757 T 31.0 -115.8 87.0 0.757 0.0 HOH
 5.465
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 SER A:137 A:137 22.0 0.191 H -61.0 -46.4
af-p50993-f1 1 P50993 88.81 0.0 SER A:145 A:145 23.0 0.2 H -63.9 -41.3
af-p05023-f1 1 P05023 88.03 0.0 SER A:147 A:147 12.0 0.104 H -60.4 -47.1