Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 42490354 | . | C | A | CCDS12594.1:NM_152296.4:c.385Gtg>Ttg_NP_689509.1:p.129V>L | Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wgu | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | VAL | A:132 | A:132 | 22.0 | 0.142 | H | -57.8 | -46.5 | 22.0 | 0.142 | 0.0 |
PC1 HOH |
4.206 9.994 |
CG2 CG1 |
C3A O |
||
| VAL | D:132 | C:132 | 30.0 | 0.194 | H | -65.1 | -53.7 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 88.01 | 0.0 |
X-RAY |
2013-10-09 | VAL | A:132 | A:132 | 24.0 | 0.155 | H | -58.8 | -47.7 | 24.0 | 0.155 | 0.0 |
NA PC1 |
9.678 4.094 |
CG1 CG2 |
NA C3C |
||
| VAL | D:132 | C:132 | 28.0 | 0.181 | H | -65.5 | -55.8 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 87.61 | 0.0 |
X-RAY |
2016-03-09 | VAL | A:137 | A:137 | 15.0 | 0.097 | H | -64.1 | -49.4 | 15.0 | 0.097 | 0.0 |
HOH |
9.397 |
CG2 |
O |
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| 4hqj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-10-02 | VAL | A:137 | A:132 | 15.0 | 0.097 | H | -58.0 | -47.6 | 15.0 | 0.097 | 0.0 |
NA |
8.594 |
CG1 |
NA |
||
| VAL | D:137 | C:132 | 17.0 | 0.11 | H | -58.9 | -47.2 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2013-06-26 | VAL | A:137 | A:132 | 13.0 | 0.084 | H | -66.3 | -45.2 | 13.0 | 0.084 | 0.0 |
HOH |
9.723 |
CG2 |
O |
||
| VAL | D:137 | C:132 | 14.0 | 0.09 | H | -66.2 | -45.5 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | VAL | A:137 | A:132 | 13.0 | 0.084 | H | -63.5 | -52.9 | 13.0 | 0.084 | 0.0 |
BUF |
9.852 |
CG2 |
O24 |
||
| VAL | D:137 | C:132 | 12.0 | 0.077 | H | -62.5 | -52.5 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2015-01-28 | VAL | A:137 | A:132 | 12.0 | 0.077 | H | -62.7 | -48.4 | 12.0 | 0.077 | 0.0 |
HOH |
9.154 |
CG2 |
O |
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| VAL | D:137 | C:132 | 12.0 | 0.077 | H | -62.7 | -48.4 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-07-07 | VAL | A:137 | A:132 | 18.0 | 0.116 | H | -63.2 | -47.3 | 18.0 | 0.116 | 0.0 |
PCW |
9.669 |
O |
C12 |
||
| VAL | D:137 | C:132 | 16.0 | 0.103 | H | -62.7 | -46.4 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 18.0 | 0.116 | H | -62.1 | -47.4 | 18.0 | 0.116 | 0.0 | ||||||
| 7d92 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 18.0 | 0.116 | H | -62.8 | -45.5 | 18.0 | 0.116 | 0.0 |
HOH |
9.948 |
CG2 |
O |
||
| 7d93 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 18.0 | 0.116 | H | -61.5 | -46.8 | 18.0 | 0.116 | 0.0 |
HOH |
9.939 |
CG2 |
O |
||
| VAL | C:132 | C:132 | 18.0 | 0.116 | H | -61.6 | -46.9 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 20.0 | 0.129 | H | -61.2 | -46.9 | 20.0 | 0.129 | 0.0 |
PCW BUF HOH |
8.963 9.978 8.863 |
O CG2 CG1 |
C12 O24 O |
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| VAL | D:132 | C:132 | 21.0 | 0.135 | H | -61.9 | -46.8 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 17.0 | 0.11 | H | -61.3 | -46.3 | 17.0 | 0.11 | 0.0 | ||||||
| VAL | D:132 | C:132 | 16.0 | 0.103 | H | -62.5 | -43.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 20.0 | 0.129 | H | -63.9 | -48.3 | 20.0 | 0.129 | 0.0 |
PCW |
9.334 |
O |
C12 |
||
| VAL | D:132 | C:132 | 20.0 | 0.129 | H | -63.7 | -48.7 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 19.0 | 0.123 | H | -60.3 | -48.2 | 19.0 | 0.123 | 0.0 |
PCW |
9.639 |
O |
C12 |
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| VAL | D:132 | C:132 | 19.0 | 0.123 | H | -59.9 | -48.9 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 19.0 | 0.123 | H | -61.1 | -46.5 | 19.0 | 0.123 | 0.0 |
HOH |
9.909 |
CG2 |
O |
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| VAL | D:132 | C:132 | 21.0 | 0.135 | H | -60.5 | -47.0 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 16.0 | 0.103 | H | -61.6 | -49.2 | 16.0 | 0.103 | 0.0 |
PCW |
9.817 |
O |
C12 |
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| VAL | D:132 | C:132 | 17.0 | 0.11 | H | -61.8 | -48.6 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 87.51 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:132 | A:132 | 20.0 | 0.129 | H | -62.0 | -45.7 | 20.0 | 0.129 | 0.0 |
PCW |
9.459 |
O |
C12 |
||
| VAL | D:132 | C:132 | 18.0 | 0.116 | H | -62.2 | -45.8 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2007-12-18 | VAL | A:114 | A:132 | 16.0 | 0.103 | H | -42.3 | -61.3 | 16.0 | 0.103 | 0.0 | ||||||
| VAL | D:114 | C:132 | 10.0 | 0.065 | H | -42.1 | -61.6 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.58 | 0.0 |
X-RAY |
2010-02-16 | VAL | A:114 | A:132 | 16.0 | 0.103 | H | -48.5 | -34.7 | 16.0 | 0.103 | 0.0 |
RB |
9.676 |
CG1 |
RB |
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| VAL | D:114 | C:132 | 12.0 | 0.077 | H | -75.1 | -13.4 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | VAL | A:108 | A:132 | 15.0 | 0.097 | H | -49.9 | -57.3 | 15.0 | 0.097 | 0.0 | ||||||
| VAL | D:108 | C:132 | 14.0 | 0.09 | H | -48.5 | -58.5 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-05-19 | VAL | A:144 | A:139 | 8.0 | 0.052 | H | -55.6 | -40.5 | 8.0 | 0.052 | 0.0 |
K HOH |
9.803 7.328 |
CG1 CG1 |
K O |
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| 3a3y | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2009-09-08 | VAL | A:144 | A:139 | 22.0 | 0.142 | H | -61.8 | -32.5 | 22.0 | 0.142 | 0.0 |
HOH |
9.015 |
CG1 |
O |
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| 5avq | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 8.0 | 0.052 | H | -55.6 | -40.5 | 8.0 | 0.052 | 0.0 |
K TL |
9.803 9.803 |
CG1 CG1 |
K TL |
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| 5avr | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.7 | -40.5 | 9.0 | 0.058 | 0.0 |
K TL |
9.803 9.803 |
CG1 CG1 |
K TL |
||
| 5avs | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.6 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5avt | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.7 | -40.5 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5avu | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.5 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5avv | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.5 | 9.0 | 0.058 | 0.0 |
TL |
9.802 |
CG1 |
TL |
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| 5avw | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.7 | -40.6 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5avx | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.6 | 9.0 | 0.058 | 0.0 |
TL |
9.804 |
CG1 |
TL |
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| 5avy | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.5 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5avz | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.7 | -40.5 | 9.0 | 0.058 | 0.0 |
TL |
9.802 |
CG1 |
TL |
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| 5aw0 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.6 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5aw1 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.5 | -40.6 | 9.0 | 0.058 | 0.0 |
TL |
9.804 |
CG1 |
TL |
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| 5aw2 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.7 | -40.5 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5aw3 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.5 | -40.6 | 9.0 | 0.058 | 0.0 |
TL |
9.803 |
CG1 |
TL |
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| 5aw4 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 8.0 | 0.052 | H | -55.7 | -40.5 | 8.0 | 0.052 | 0.0 |
K RB |
9.802 9.802 |
CG1 CG1 |
K RB |
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| 5aw5 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 9.0 | 0.058 | H | -55.6 | -40.5 | 9.0 | 0.058 | 0.0 |
K RB |
9.803 9.803 |
CG1 CG1 |
K RB |
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| 5aw6 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 8.0 | 0.052 | H | -55.7 | -40.5 | 8.0 | 0.052 | 0.0 |
K RB |
9.803 9.803 |
CG1 CG1 |
K RB |
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| 5aw7 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 8.0 | 0.052 | H | -55.7 | -40.5 | 8.0 | 0.052 | 0.0 |
RB |
9.802 |
CG1 |
RB |
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| 5aw8 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 8.0 | 0.052 | H | -55.7 | -40.5 | 8.0 | 0.052 | 0.0 |
RB |
9.802 |
CG1 |
RB |
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| 5aw9 | 1 | Q4H132 | 85.56 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:144 | A:139 | 7.0 | 0.045 | H | -51.6 | -45.0 | 7.0 | 0.045 | 0.0 |
K HOH |
9.939 7.189 |
CG1 CG1 |
K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p13637-f1 | 1 | P13637 | 100.0 | 0.0 | VAL | A:129 | A:129 | 13.0 | 0.084 | H | -58.4 | -48.5 | |
| af-p50993-f1 | 1 | P50993 | 88.81 | 0.0 | VAL | A:137 | A:137 | 14.0 | 0.09 | H | -58.1 | -48.3 | |
| af-p05023-f1 | 1 | P05023 | 88.03 | 0.0 | VAL | A:139 | A:139 | 11.0 | 0.071 | H | -59.6 | -46.4 | |