Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 47341747 . G A CCDS12693.1:NM_021575.2:c.272aCg>aTg_NP_067586.1:p.91T>M Homo sapiens adaptor-related protein complex 2, sigma 1 subunit (AP2S1), transcript variant AP17, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2jkr 3 P62743 100.0 1e-102 X-RAY
 2008-10-28 THR D:129 I:129 108.0 0.771 H -61.8 -56.0 NA NA NA
THR I:129 S:129 108.0 0.771 H -64.6 -56.9 75.0 0.536 0.235 A:P17427:0.236
2jkt 3 P62743 100.0 1e-102 X-RAY
 2008-10-28 THR D:129 I:129 118.0 0.843 H -65.7 -44.6 NA NA NA
THR I:129 S:129 115.0 0.821 H -66.6 -44.8 83.0 0.593 0.228 A:P17427:0.229
2vgl 4 P62743 100.0 1e-102 X-RAY
 2007-12-25 THR D:129 S:129 117.0 0.836 H -74.1 -51.5 91.0 0.65 0.186 A:Q66HM2:0.186
 HOH
 9.994
 CG2
 O
2xa7 5 P62743 100.0 1e-102 X-RAY
 2010-07-21 THR E:129 S:129 95.0 0.679 H -49.2 -88.6 72.0 0.514 0.165 A:Q66HM2:0.164
4nee 1 P62744 100.0 1e-102 X-RAY
 2014-01-29 THR A:129 D:129 105.0 0.75 H -61.0 -49.5 69.0 0.493 0.257 F:Q66HM2:0.257
THR B:129 L:129 91.0 0.65 H -61.8 -47.9 NA NA NA
THR C:129 F:129 88.0 0.629 H -61.8 -46.8 NA NA NA
THR D:129 I:129 106.0 0.757 H -62.8 -47.2 NA NA NA
4uqi 4 P62743 100.0 1e-102 X-RAY
 2014-07-30 THR D:129 S:129 110.0 0.786 H -65.5 -51.7 87.0 0.621 0.165 A:P18484:0.164
6owo 4 P62744 100.0 1e-102 EM
 2019-09-11 THR D:129 S:129 113.0 0.807 H -69.0 -41.7 92.0 0.657 0.15 A:None:0.15
6oxl 4 P62744 100.0 1e-102 EM
 2019-09-11 THR D:129 S:129 106.0 0.757 H -78.3 -47.6 84.0 0.6 0.157 A:None:0.157
6qh5 5 P62743 100.0 1e-102 X-RAY
 2019-09-04 THR E:129 S:129 109.0 0.779 H -66.8 -47.9 87.0 0.621 0.158 A:Q66HM2:0.157
6qh6 7 P62743 100.0 1e-102 X-RAY
 2019-09-04 THR G:129 S:129 103.0 0.736 H -59.2 -44.3 85.0 0.607 0.129 A:Q66HM2:0.129
6qh7 6 P62743 100.0 1e-102 X-RAY
 2019-09-04 THR G:129 S:129 108.0 0.771 H -59.9 -47.7 85.0 0.607 0.164 A:Q66HM2:0.164
6yae 4 P62743 100.0 1e-102 EM
 2020-07-29 THR D:129 S:129 108.0 0.771 H -66.4 -48.8 69.0 0.493 0.278 A:Q66HM2:0.279
6yaf 5 P62743 100.0 1e-102 EM
 2020-07-29 THR E:129 S:129 106.0 0.757 H -60.0 -48.0 86.0 0.614 0.143 A:P18484:0.143
6yah 4 P62743 100.0 1e-102 EM
 2020-07-29 THR D:129 S:129 106.0 0.757 H -60.0 -48.0 88.0 0.629 0.128 A:P18484:0.129
6uri 2 P53680 99.3 4e-102 X-RAY
 2020-07-29 THR B:129 S:129 84.0 0.6 H -57.7 -49.5 58.0 0.414 0.186 A:Q66HM2:0.186
6owt 5 P62744 98.59 6e-100 EM
 2019-09-25 THR F:129 S:129 67.0 NA H -70.5 -40.7 52.0 NA NA A:Q66HM2:NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p53680-f1 1 P53680 100.0 6e-103 THR A:129 A:129 110.0 0.786 H -57.8 -41.9