Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 47349359 . C A CCDS12693.1:NM_021575.2:c.44cGc>cTc_NP_067586.1:p.15R>L Homo sapiens adaptor-related protein complex 2, sigma 1 subunit (AP2S1), transcript variant AP17, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2jkr 3 P62743 100.0 1e-102 X-RAY
 2008-10-28 ARG D:15 I:15 67.0 0.298 E -127.1 0.7 NA NA NA
ARG I:15 S:15 65.0 0.289 E -129.7 2.6 28.0 0.124 0.165 A:P17427:0.16
G:B0AZV7:0.067
2jkt 3 P62743 100.0 1e-102 X-RAY
 2008-10-28 ARG D:15 I:15 73.0 0.324 E -132.6 -8.1 NA NA NA
ARG I:15 S:15 73.0 0.324 E -139.0 -5.5 33.0 0.147 0.177 A:P17427:0.156
G:B0AZV7:0.062
2vgl 4 P62743 100.0 1e-102 X-RAY
 2007-12-25 ARG D:15 S:15 54.0 0.24 E -114.5 -14.7 44.0 0.196 0.044 B:P63010:0.013
A:Q66HM2:0.031
 HOH
 7.831
 NE
 O
2xa7 5 P62743 100.0 1e-102 X-RAY
 2010-07-21 ARG E:15 S:15 71.0 0.316 E -71.5 -18.3 52.0 0.231 0.085 A:Q66HM2:0.084
 SO4
 3.547
 NH2
 O1
4nee 1 P62744 100.0 1e-102 X-RAY
 2014-01-29 ARG A:15 D:15 66.0 0.293 E -78.9 -34.8 49.0 0.218 0.075 F:Q66HM2:0.062
L:Q90VU7:0.062
ARG B:15 L:15 56.0 0.249 E -78.9 -36.9 NA NA NA
ARG C:15 F:15 51.0 0.227 E -82.0 -34.2 NA NA NA
ARG D:15 I:15 62.0 0.276 E -79.4 -34.7 NA NA NA
4uqi 4 P62743 100.0 1e-102 X-RAY
 2014-07-30 ARG D:15 S:15 59.0 0.262 E -119.7 -9.1 51.0 0.227 0.035 B:P63010:0.009
A:P18484:0.027
 HOH
 7.959
 NE
 O
6owo 4 P62744 100.0 1e-102 EM
 2019-09-11 ARG D:15 S:15 47.0 0.209 E -120.8 -16.8 38.0 0.169 0.04 B:Q9DBG3:0.009
A:None:0.031
6oxl 4 P62744 100.0 1e-102 EM
 2019-09-11 ARG D:15 S:15 54.0 0.24 E -113.6 -51.6 41.0 0.182 0.058 B:Q9DBG3:0.031
A:None:0.031
6qh5 5 P62743 100.0 1e-102 X-RAY
 2019-09-04 ARG E:15 S:15 31.0 0.138 E -110.1 -17.6 21.0 0.093 0.045 A:Q66HM2:0.036
B:P63010:0.013
6qh6 7 P62743 100.0 1e-102 X-RAY
 2019-09-04 ARG G:15 S:15 69.0 0.307 E -71.2 -15.6 40.0 0.178 0.129 A:Q66HM2:0.116
F:None:0.018
6qh7 6 P62743 100.0 1e-102 X-RAY
 2019-09-04 ARG G:15 S:15 72.0 0.32 E -73.4 -6.5 41.0 0.182 0.138 A:Q66HM2:0.12
F:None:0.022
6yae 4 P62743 100.0 1e-102 EM
 2020-07-29 ARG D:15 S:15 69.0 0.307 E -78.2 -28.2 43.0 0.191 0.116 B:P63010:0.058
A:Q66HM2:0.084
6yaf 5 P62743 100.0 1e-102 EM
 2020-07-29 ARG E:15 S:15 123.0 0.547 S -80.1 -13.6 96.0 0.427 0.12 A:P18484:0.12
6yah 4 P62743 100.0 1e-102 EM
 2020-07-29 ARG D:15 S:15 125.0 0.556 S -80.0 -13.6 98.0 0.436 0.12 A:P18484:0.12
6uri 2 P53680 99.3 4e-102 X-RAY
 2020-07-29 ARG B:15 S:15 62.0 0.276 E -86.9 -21.7 41.0 0.182 0.094 A:Q66HM2:0.067
C:Q90VU7:0.071
6owt 5 P62744 98.59 6e-100 EM
 2019-09-25 ARG F:15 S:15 85.0 0.378 E -93.1 -43.0 73.0 0.324 0.054 A:Q66HM2:0.053

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p53680-f1 1 P53680 100.0 6e-103 ARG A:15 A:15 65.0 0.289 E -104.1 -28.2