Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 49303026 | . | A | C | CCDS12735.1:NM_001190.3:c.601Ttc>Gtc_NP_001181.2:p.201F>V | Homo sapiens branched chain amino acid transaminase 2 (BCAT2), transcript variant a, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5bwr | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PHE | A:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5bwt | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PHE | A:178 | A:174 | 56.0 | 0.267 | -98.9 | 157.5 | 56.0 | 0.267 | 0.0 |
4VS HOH |
3.390 4.105 |
CZ CE1 |
C7 O |
|||
| PHE | B:178 | B:174 | 114.0 | 0.543 | -108.2 | 360.0 | 114.0 | 0.543 | 0.0 |
4VS HOH |
4.101 2.966 |
CE2 N |
C7 O |
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| 5bwu | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PHE | A:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:178 | B:174 | 62.0 | 0.295 | -105.9 | 360.0 | 62.0 | 0.295 | 0.0 |
4VR EDO HOH |
6.628 8.016 6.614 |
CZ CE1 N |
C18 O1 O |
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| 5bwv | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PHE | A:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5bww | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PHE | A:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5bwx | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PHE | A:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:178 | B:174 | 20.0 | 0.095 | S | -109.6 | 153.7 | 20.0 | 0.095 | 0.0 |
4W4 EDO HOH |
6.872 8.565 3.481 |
CZ N CD2 |
C16 O2 O |
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| 5cr5 | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2015-08-12 | PHE | A:178 | A:174 | 23.0 | 0.11 | S | -107.8 | 88.9 | 23.0 | 0.11 | 0.0 |
EL1 CL HOH |
7.083 7.280 2.957 |
CZ CE2 N |
C36 CL O |
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| PHE | B:178 | B:174 | 11.0 | 0.052 | S | -109.8 | 127.6 | 11.0 | 0.052 | 0.0 |
EL1 CL HOH |
6.948 7.361 3.105 |
CZ CD2 N |
C36 CL O |
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| 5hne | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | PHE | A:178 | A:174 | 25.0 | 0.119 | S | -107.3 | 91.7 | 25.0 | 0.119 | 0.0 |
EL2 HOH |
6.411 2.596 |
N N |
C01 O |
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| PHE | B:178 | B:174 | 20.0 | 0.095 | S | -104.9 | 133.5 | 20.0 | 0.095 | 0.0 |
EL2 HOH |
6.297 3.252 |
N CD1 |
C01 O |
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| 5i5s | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 36.0 | 0.171 | S | -94.6 | 137.9 | 36.0 | 0.171 | 0.0 |
NVU HOH |
8.118 3.113 |
CE2 N |
OXT O |
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| PHE | B:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5i5t | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 39.0 | 0.186 | S | -135.2 | 157.1 | 39.0 | 0.186 | 0.0 |
67X HOH |
7.495 3.159 |
CE2 CD2 |
O15 O |
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| PHE | B:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5i5u | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 24.0 | 0.114 | S | -89.2 | 156.9 | 24.0 | 0.114 | 0.0 |
67Y HOH |
5.932 3.281 |
CE2 N |
O1 O |
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| PHE | B:178 | B:174 | 87.0 | 0.414 | -108.1 | 360.0 | 87.0 | 0.414 | 0.0 |
67Y HOH |
5.745 3.120 |
CE2 N |
O1 O |
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| 5i5v | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 23.0 | 0.11 | S | -109.7 | 90.9 | 23.0 | 0.11 | 0.0 |
68A HOH |
6.064 4.484 |
N N |
C9 O |
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| PHE | B:178 | B:174 | 13.0 | 0.062 | S | -104.9 | 94.5 | 13.0 | 0.062 | 0.0 |
68A HOH |
5.960 3.002 |
N N |
C9 O |
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| 5i5w | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:178 | B:174 | 80.0 | 0.381 | -86.0 | 360.0 | 80.0 | 0.381 | 0.0 |
68B HOH |
8.444 4.074 |
N CE1 |
C7 O |
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| 5i5x | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 54.0 | 0.257 | -108.0 | 360.0 | 54.0 | 0.257 | 0.0 |
68C CL HOH |
7.678 7.260 3.002 |
N CD2 CD1 |
C7 CL O |
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| PHE | B:178 | B:174 | 14.0 | 0.067 | S | -107.0 | 110.8 | 14.0 | 0.067 | 0.0 |
68C CL HOH |
7.423 7.280 3.082 |
N N N |
C7 CL O |
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| 5i5y | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 25.0 | 0.119 | S | -94.2 | 95.2 | 25.0 | 0.119 | 0.0 |
68D EDO HOH |
6.768 4.498 3.425 |
N N N |
C7 O1 O |
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| PHE | B:178 | B:174 | 23.0 | 0.11 | S | -115.6 | 74.5 | 23.0 | 0.11 | 0.0 |
68D CL HOH |
7.314 7.155 3.107 |
N N N |
C7 CL O |
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| 5i60 | 1 | O15382 | 100.0 | 0.0 |
X-RAY |
2016-03-23 | PHE | A:178 | A:174 | 18.0 | 0.086 | S | -98.7 | 124.9 | 18.0 | 0.086 | 0.0 |
67W HOH |
5.980 2.811 |
N N |
C17 O |
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| PHE | B:178 | B:174 | 16.0 | 0.076 | S | -93.2 | 109.6 | 16.0 | 0.076 | 0.0 |
67W HOH |
5.926 3.129 |
N N |
C17 O |
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| 1ekf | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2001-03-08 | PHE | A:174 | A:174 | 173.0 | 0.824 | T | -136.3 | -64.4 | 173.0 | 0.824 | 0.0 |
HOH |
4.385 |
N |
O |
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| PHE | B:174 | B:174 | 29.0 | 0.138 | S | -105.5 | 109.0 | 29.0 | 0.138 | 0.0 |
HOH |
4.753 |
CE1 |
O |
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| 1ekp | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2001-03-09 | PHE | A:174 | A:174 | 67.0 | 0.319 | T | 16.4 | -107.2 | 67.0 | 0.319 | 0.0 |
HOH |
2.953 |
CE2 |
O |
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| PHE | B:174 | B:174 | 26.0 | 0.124 | S | -107.4 | 93.0 | 26.0 | 0.124 | 0.0 |
HOH |
3.342 |
CE2 |
O |
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| 1ekv | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2001-03-09 | PHE | A:174 | A:174 | 38.0 | 0.181 | S | -146.8 | 160.2 | 38.0 | 0.181 | 0.0 |
HOH |
4.111 |
CB |
O |
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| PHE | B:174 | B:174 | 30.0 | 0.143 | S | -141.6 | 160.7 | 30.0 | 0.143 | 0.0 |
HOH |
3.436 |
CE2 |
O |
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| 1kt8 | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2002-11-20 | PHE | A:174 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:174 | B:674 | 29.0 | 0.138 | S | -106.5 | 119.4 | 29.0 | 0.138 | 0.0 |
HOH |
4.673 |
CE1 |
O |
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| 1kta | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2002-11-20 | PHE | A:174 | A:174 | 156.0 | 0.743 | S | 62.6 | 90.9 | 156.0 | 0.743 | 0.0 |
HOH |
6.064 |
N |
O |
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| PHE | B:174 | B:674 | 26.0 | 0.124 | S | -94.0 | 124.0 | 26.0 | 0.124 | 0.0 |
HOH |
6.936 |
CD1 |
O |
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| 2a1h | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2005-09-06 | PHE | A:174 | A:174 | 24.0 | 0.114 | S | -91.1 | 125.7 | 24.0 | 0.114 | 0.0 |
HOH |
4.295 |
CE2 |
O |
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| PHE | B:174 | B:174 | 21.0 | 0.1 | S | -118.7 | 85.1 | 21.0 | 0.1 | 0.0 |
HOH |
3.066 |
N |
O |
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| 2hhf | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2006-10-24 | PHE | A:174 | A:174 | 30.0 | 0.143 | S | -88.1 | 138.0 | 30.0 | 0.143 | 0.0 |
HOH |
3.863 |
CE1 |
O |
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| 2hhf | 2 | O15382 | 99.73 | 0.0 |
X-RAY |
2006-10-24 | PHE | B:174 | B:674 | 24.0 | 0.114 | S | -124.4 | 110.8 | 24.0 | 0.114 | 0.0 |
EPE HOH |
8.106 2.912 |
N N |
O1S O |
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| 5mpr | 1 | O15382 | 99.73 | 0.0 |
X-RAY |
2017-07-19 | PHE | A:175 | A:174 | 38.0 | 0.181 | S | -136.4 | 154.4 | 38.0 | 0.181 | 0.0 |
HOH |
6.303 |
O |
O |
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| 2hg8 | 1 | O15382 | 99.45 | 0.0 |
X-RAY |
2006-10-24 | PHE | A:174 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:174 | B:674 | 15.0 | 0.071 | S | -116.9 | 87.6 | 15.0 | 0.071 | 0.0 |
HOH |
3.084 |
N |
O |
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| 2hgx | 1 | O15382 | 99.45 | 0.0 |
X-RAY |
2006-10-24 | PHE | A:174 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:174 | B:674 | 17.0 | 0.081 | S | -119.4 | 82.0 | 17.0 | 0.081 | 0.0 |
HOH |
3.220 |
N |
O |
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| 2hgw | 1 | O15382 | 99.45 | 0.0 |
X-RAY |
2006-10-24 | PHE | A:174 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:174 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6prx | 1 | O15382 | 99.45 | 0.0 |
X-RAY |
2020-01-22 | PHE | A:192 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PHE | B:192 | B:174 | 19.0 | 0.09 | S | -130.0 | 102.2 | 19.0 | 0.09 | 0.0 | |||||||||||||
| 2hdk | 1 | O15382 | 99.18 | 0.0 |
X-RAY |
2006-10-24 | PHE | A:174 | A:174 | 17.0 | 0.081 | S | -99.2 | 101.6 | 17.0 | 0.081 | 0.0 |
HOH |
3.880 |
CZ |
O |
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| PHE | B:174 | B:674 | 41.0 | 0.195 | -145.5 | 77.2 | 41.0 | 0.195 | 0.0 |
HOH |
4.904 |
N |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o15382-f1 | 1 | O15382 | 100.0 | 0.0 | PHE | A:201 | A:201 | 33.0 | 0.157 | S | -134.7 | 150.5 | |