Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 49459071 . A C CCDS12742.1:NM_138761.3:c.214Agt>Cgt_NP_620116.1:p.72S>R Homo sapiens BCL2 associated X, apoptosis regulator (BAX), transcript variant alpha, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2lr1 1 Q07812 100.0 2e-140 NMR
 2012-12-05 SER A:72 A:72 84.0 0.73 T -96.4 7.1 84.0 0.73 0.0
4s0p 1 Q07812 99.48 3e-139 X-RAY
 2016-07-20 SER A:72 A:72 90.0 0.783 T -92.4 -2.5 90.0 0.783 0.0
SER B:72 B:72 81.0 0.704 T -100.9 7.1 NA NA NA
6eb6 1 Q07812 99.48 4e-139 X-RAY
 2019-04-10 SER A:72 A:72 78.0 0.678 T -99.9 13.8 78.0 0.678 0.0 FMT
HOH
 5.858
6.023
 OG
OG
 O1
O
4s0o 1 Q07812 99.48 6e-139 X-RAY
 2016-07-20 SER A:72 A:72 94.0 0.817 T -83.7 1.6 94.0 0.817 0.0 HOH
 5.037
 C
 O
SER B:72 B:72 90.0 0.783 T -91.9 4.3 85.0 0.739 0.044 A:Q07812:0.043
 HOH
 2.601
 OG
 O
5w5x 3 Q07812 98.44 1e-136 X-RAY
 2018-06-27 SER C:72 A:72 81.0 0.704 T -100.9 16.0 81.0 0.704 0.0 HOH
 6.600
 N
 O
5w60 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 SER A:72 A:72 70.0 0.609 T -96.5 2.2 70.0 0.609 0.0 HOH
 2.826
 OG
 O
5w61 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 SER A:72 A:72 66.0 0.574 T -94.1 -0.6 66.0 0.574 0.0 HOH
 7.643
 N
 O
5w62 1 Q07813 91.15 3e-125 X-RAY
 2018-06-27 SER A:72 A:72 89.0 0.774 T -93.3 -7.5 89.0 0.774 0.0 HOH
 8.506
 C
 O
4bd2 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 SER A:72 A:72 79.0 0.687 H -96.6 -17.2 79.0 0.687 0.0 HOH
 8.391
 N
 O
4bd6 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 SER A:72 A:72 91.0 0.791 H -95.9 -17.7 91.0 0.791 0.0
4bd7 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 SER A:72 A:72 87.0 0.757 T -106.4 -3.7 87.0 0.757 0.0 HOH
 2.600
 OG
 O
SER B:72 B:72 84.0 0.73 G -106.7 3.8 84.0 0.73 0.0
SER C:72 C:72 107.0 0.93 G -101.5 36.3 NA NA NA
SER D:72 D:72 106.0 0.922 T -88.7 7.9 NA NA NA
4bd8 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 SER A:72 A:72 84.0 0.73 T -112.1 20.3 84.0 0.73 0.0 EDO
HOH
 4.095
2.675
 O
OG
 O2
O
SER B:72 B:72 84.0 0.73 T -108.0 14.8 84.0 0.73 0.0 HOH
 2.794
 O
 O
SER C:72 C:72 99.0 0.861 S -75.5 -17.0 NA NA NA
SER D:72 D:72 90.0 0.783 S -96.9 5.1 NA NA NA
4zii 1 Q07812 98.82 1e-121 X-RAY
 2015-07-22 SER A:72 A:72 92.0 0.8 T -94.4 21.4 92.0 0.8 0.0 HOH
 8.498
 N
 O
4zie 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 SER A:72 A:72 91.0 0.791 T -85.8 -2.4 91.0 0.791 0.0 HOH
 3.317
 O
 O
4zif 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 SER A:72 A:72 84.0 0.73 T -83.2 -4.6 84.0 0.73 0.0
4zig 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 SER A:72 A:72 89.0 0.774 H -84.7 -21.7 89.0 0.774 0.0 HOH
 7.158
 N
 O
4zih 1 Q07812 98.78 2e-116 X-RAY
 2015-07-22 SER A:72 A:72 84.0 0.73 T -84.2 -5.5 84.0 0.73 0.0
5w5z 3 Q07812 98.14 3e-113 X-RAY
 2018-06-27 SER C:41 A:72 81.0 0.704 T -87.6 0.7 81.0 0.704 0.0 HOH
 2.767
 OG
 O
6l8v 1 Q07812 93.75 4e-48 NMR
 2020-11-11 SER A:25 A:72 90.0 0.783 H -86.0 -11.3 90.0 0.783 0.0
SER B:25 B:72 84.0 0.73 T -86.1 7.2 84.0 0.73 0.0
4bdu 1 P42212,Q07812 97.37 4e-45 X-RAY
 2013-02-13 SER A:253 A:1072 76.0 0.661 H -97.9 -8.4 76.0 0.661 0.0
SER B:253 B:1072 76.0 0.661 H -97.5 -8.3 76.0 0.661 0.0 HOH
 5.708
 N
 O
SER C:253 C:1072 78.0 0.678 H -97.8 -8.3 NA NA NA
SER D:253 D:1072 77.0 0.67 H -97.7 -8.6 NA NA NA
3pk1 2 Q07812 100.0 2e-17 X-RAY
 2010-12-29 SER B:25 B:72 73.0 0.635 H -59.3 -38.4 73.0 0.635 0.0 CD
HOH
 9.278
3.868
 N
N
 CD
O
SER D:25 D:72 74.0 0.643 H -59.3 -39.3 NA NA NA
3pl7 2 Q07812 100.0 2e-17 X-RAY
 2010-12-29 SER B:25 C:72 68.0 0.591 H -55.3 -49.4 68.0 0.591 0.0 HOH
 3.721
 N
 O
4bd6 2 Q07812 100.0 2e-17 X-RAY
 2013-02-13 SER B:25 C:72 99.0 0.861 H -52.4 -36.1 99.0 0.861 0.0 HOH
 8.520
 N
 O
2xa0 2 Q07813 96.67 2e-13 X-RAY
 2010-11-24 SER C:21 C:72 76.0 0.661 H -53.2 -48.3 76.0 0.661 0.0 HOH
 7.516
 N
 O
SER D:21 D:72 69.0 0.6 H -53.7 -39.7 NA NA NA
4uf2 2 Q07812 100.0 6e-13 X-RAY
 2015-08-05 SER B:23 B:24 87.0 0.757 T -68.3 -25.6 87.0 0.757 0.0
5ua5 2 F1RIQ4 100.0 6e-13 X-RAY
 2017-01-04 SER B:23 B:47 61.0 0.53 -74.7 142.5 53.0 0.461 0.069 A:D0Q0E8:0.07
 HOH
 6.272
 OG
 O
6trr 2 Q07812 100.0 6e-13 X-RAY
 2020-06-03 SER B:23 B:170 71.0 0.617 H -71.6 -40.8 71.0 0.617 0.0 HOH
 6.882
 C
 O
6xy6 2 Q07812 100.0 6e-13 X-RAY
 2020-07-29 SER B:23 B:72 98.0 0.852 H -61.6 -43.0 98.0 0.852 0.0
SER D:23 D:72 107.0 0.93 H -58.0 -45.3 NA NA NA
SER F:23 F:72 56.0 0.487 H -64.1 -42.3 NA NA NA
SER H:23 H:72 66.0 0.574 H -61.9 -44.1 NA NA NA
SER J:23 J:72 62.0 0.539 H -63.2 -48.2 NA NA NA
SER L:23 L:72 65.0 0.565 H -63.0 -45.2 NA NA NA
SER N:23 N:72 105.0 0.913 H -59.2 -42.6 NA NA NA
SER P:23 P:72 99.0 0.861 H -54.8 -43.4 NA NA NA
7adt 2 Q07812 100.0 6e-13 X-RAY
 2021-10-06 SER B:23 U:72 66.0 0.574 H -66.7 -29.9 66.0 0.574 0.0 MG
HOH
 7.020
6.187
 HG
H
 MG
O
SER D:23 C:72 65.0 0.565 H -86.4 -31.3 65.0 0.565 0.0 MG
 6.863
 O
 MG

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q07812-f1 1 Q07812 100.0 1e-140 SER A:72 A:72 76.0 0.661 H -75.4 -18.6