Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 49459487 . G A CCDS12742.1:NM_138761.3:c.266cGa>cAa_NP_620116.1:p.89R>Q Homo sapiens BCL2 associated X, apoptosis regulator (BAX), transcript variant alpha, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2lr1 1 Q07812 100.0 2e-140 NMR
 2012-12-05 ARG A:89 A:89 159.0 0.707 H -85.2 -35.0 159.0 0.707 0.0
4s0p 1 Q07812 99.48 3e-139 X-RAY
 2016-07-20 ARG A:89 A:89 135.0 0.6 H -50.1 -59.7 132.0 0.587 0.013 A:Q07812:0.013
ARG B:89 B:89 107.0 0.476 H -48.1 -50.2 NA NA NA
6eb6 1 Q07812 99.48 4e-139 X-RAY
 2019-04-10 ARG A:89 A:89 143.0 0.636 H -61.8 -36.2 143.0 0.636 0.0 HOH
 3.238
 N
 O
4s0o 1 Q07812 99.48 6e-139 X-RAY
 2016-07-20 ARG A:89 A:89 133.0 0.591 H -51.5 -54.0 133.0 0.591 0.0 HOH
 2.650
 NE
 O
ARG B:89 B:89 120.0 0.533 H -60.8 -55.3 120.0 0.533 0.0 HOH
 2.651
 NE
 O
5w5x 3 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ARG C:89 A:89 146.0 0.649 H -61.6 -53.2 146.0 0.649 0.0
5w60 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ARG A:89 A:89 119.0 0.529 H -57.8 -50.8 119.0 0.529 0.0 SO4
HOH
 2.419
3.000
 NH2
N
 O1
O
5w61 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ARG A:89 A:89 145.0 0.644 H -70.9 -37.3 145.0 0.644 0.0 HOH
 6.621
 NE
 O
5w62 1 Q07813 91.15 3e-125 X-RAY
 2018-06-27 ARG A:89 A:89 38.0 NA H -65.7 -38.9 38.0 NA NA HOH
 7.641
 N
 O
4bd2 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ARG A:89 A:89 178.0 0.791 H -67.6 -45.4 123.0 0.547 0.244 A:Q07812:0.244
 HOH
 2.761
 NH2
 O
4bd6 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ARG A:89 A:89 181.0 0.804 H -67.2 -46.0 125.0 0.556 0.248 A:Q07812:0.249
 HOH
 2.684
 NH1
 O
4bd7 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ARG A:89 A:89 167.0 0.742 H -59.3 -20.5 112.0 0.498 0.244 B:Q07812:0.244
 PR
HOH
 6.188
5.752
 NH2
NH2
 PR
O
ARG B:89 B:89 166.0 0.738 H -69.6 -62.9 122.0 0.542 0.196 A:Q07812:0.196
 PR
HOH
 7.896
4.467
 NH2
NH2
 PR
O
ARG C:89 C:89 58.0 NA H -68.6 -67.7 NA NA NA
ARG D:89 D:89 78.0 NA H -54.2 -64.6 NA NA NA
4bd8 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ARG A:89 A:89 200.0 0.889 H -58.2 -41.3 163.0 0.724 0.165 B:Q07812:0.164
 EDO
PR
HOH
 3.291
8.730
2.426
 CB
NH1
O
 O1
PR
O
ARG B:89 B:89 190.0 0.844 H -63.9 -40.7 146.0 0.649 0.195 A:Q07812:0.196
 PR
EDO
HOH
 7.805
8.893
2.260
 NH2
NH1
NH2
 PR
O1
O
ARG C:89 C:89 215.0 0.956 H -61.4 -36.6 NA NA NA
ARG D:89 D:89 192.0 0.853 T -63.3 -39.9 NA NA NA
4zii 1 Q07812 98.82 1e-121 X-RAY
 2015-07-22 ARG A:89 A:89 183.0 0.813 H -65.6 -45.5 130.0 0.578 0.235 A:Q07812:0.236
 EDO
HOH
 5.692
2.669
 N
NE
 C2
O
4zie 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ARG A:89 A:89 175.0 0.778 H -67.1 -44.8 118.0 0.524 0.254 A:Q07812:0.253
 HOH
 2.930
 NH2
 O
4zif 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ARG A:89 A:89 176.0 0.782 H -67.3 -44.2 122.0 0.542 0.24 A:Q07812:0.24
 HOH
 2.906
 NH2
 O
4zig 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ARG A:89 A:89 177.0 0.787 H -64.4 -42.3 177.0 0.787 0.0 HOH
 2.798
 NH1
 O
4zih 1 Q07812 98.78 2e-116 X-RAY
 2015-07-22 ARG A:89 A:89 176.0 0.782 H -67.1 -44.7 120.0 0.533 0.249 A:Q07812:0.249
 HOH
 2.650
 NH1
 O
5w5z 3 Q07812 98.14 3e-113 X-RAY
 2018-06-27 ARG C:58 NA:NA DO NA DO DO DO NA NA NA
6l8v 1 Q07812 93.75 4e-48 NMR
 2020-11-11 ARG A:42 A:89 151.0 0.671 H -63.8 -20.2 151.0 0.671 0.0
ARG B:42 B:89 216.0 0.96 H -71.5 -36.1 216.0 0.96 0.0
4bdu 1 P42212,Q07812 97.37 4e-45 X-RAY
 2013-02-13 ARG A:270 A:1089 212.0 0.942 H -50.5 -45.9 212.0 0.942 0.0 HOH
 6.888
 CB
 O
ARG B:270 B:1089 212.0 0.942 H -51.0 -45.4 212.0 0.942 0.0 HOH
 7.492
 N
 O
ARG C:270 C:1089 212.0 0.942 H -51.2 -45.2 NA NA NA
ARG D:270 D:1089 213.0 0.947 H -50.5 -45.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q07812-f1 1 Q07812 100.0 1e-140 ARG A:89 A:89 158.0 0.702 H -61.5 -51.7