Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 49459508 . C A CCDS12742.1:NM_138761.3:c.287gCa>gAa_NP_620116.1:p.96A>E Homo sapiens BCL2 associated X, apoptosis regulator (BAX), transcript variant alpha, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2lr1 1 Q07812 100.0 2e-140 NMR
 2012-12-05 ALA A:96 A:96 9.0 0.078 H -55.0 -27.7 9.0 0.078 0.0
4s0p 1 Q07812 99.48 3e-139 X-RAY
 2016-07-20 ALA A:96 A:96 0.0 0.0 H -56.2 -35.7 0.0 0.0 0.0
ALA B:96 B:96 0.0 0.0 H -54.3 -49.6 NA NA NA
6eb6 1 Q07812 99.48 4e-139 X-RAY
 2019-04-10 ALA A:96 A:96 0.0 0.0 H -58.3 -49.7 0.0 0.0 0.0 HOH
 6.123
 C
 O
4s0o 1 Q07812 99.48 6e-139 X-RAY
 2016-07-20 ALA A:96 A:96 0.0 0.0 H -56.3 -51.4 0.0 0.0 0.0 HOH
 4.748
 O
 O
ALA B:96 B:96 0.0 0.0 H -60.5 -50.8 0.0 0.0 0.0 HOH
 4.905
 O
 O
5w5x 3 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ALA C:96 A:96 0.0 0.0 H -61.4 -43.5 0.0 0.0 0.0 HOH
 4.672
 O
 O
5w60 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ALA A:96 A:96 0.0 0.0 H -57.5 -53.7 0.0 0.0 0.0 HOH
 5.221
 O
 O
5w61 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ALA A:96 A:96 0.0 0.0 H -61.9 -40.8 0.0 0.0 0.0 HOH
 4.963
 O
 O
5w62 1 Q07813 91.15 3e-125 X-RAY
 2018-06-27 ALA A:96 A:96 0.0 0.0 H -62.4 -42.3 0.0 0.0 0.0 HOH
 5.045
 O
 O
4bd2 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ALA A:96 A:96 16.0 0.139 H -62.4 -50.7 0.0 0.0 0.139 A:Q07812:0.139
 HOH
 4.314
 CB
 O
4bd6 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ALA A:96 A:96 15.0 0.13 H -63.0 -49.6 0.0 0.0 0.13 A:Q07812:0.13
 HOH
 7.979
 N
 O
4bd7 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ALA A:96 A:96 14.0 0.122 H -57.8 -35.3 0.0 0.0 0.122 B:Q07812:0.122
 HOH
 7.968
 CB
 O
ALA B:96 B:96 14.0 0.122 H -65.0 -32.7 0.0 0.0 0.122 A:Q07812:0.122
 HOH
 8.422
 CB
 O
ALA C:96 C:96 17.0 0.148 H -68.4 -34.1 NA NA NA
ALA D:96 D:96 12.0 0.104 H -62.7 -41.9 NA NA NA
4bd8 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ALA A:96 A:96 13.0 0.113 H -56.1 -50.8 0.0 0.0 0.113 B:Q07812:0.113
 HOH
 5.085
 O
 O
ALA B:96 B:96 14.0 0.122 H -67.6 -41.1 0.0 0.0 0.122 A:Q07812:0.122
 HOH
 5.043
 O
 O
ALA C:96 C:96 14.0 0.122 H -70.1 -45.5 NA NA NA
ALA D:96 D:96 12.0 0.104 H -51.9 -43.5 NA NA NA
4zii 1 Q07812 98.82 1e-121 X-RAY
 2015-07-22 ALA A:96 A:96 18.0 0.157 H -55.1 -50.3 0.0 0.0 0.157 A:Q07812:0.157
 HOH
 5.247
 O
 O
4zie 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ALA A:96 A:96 16.0 0.139 H -55.9 -48.2 0.0 0.0 0.139 A:Q07812:0.139
 HOH
 4.254
 CB
 O
4zif 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ALA A:96 A:96 17.0 0.148 H -61.3 -44.7 0.0 0.0 0.148 A:Q07812:0.148
 HOH
 8.833
 O
 O
4zig 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ALA A:96 A:96 16.0 0.139 H -59.0 -50.2 16.0 0.139 0.0 HOH
 4.969
 O
 O
4zih 1 Q07812 98.78 2e-116 X-RAY
 2015-07-22 ALA A:96 A:96 16.0 0.139 H -61.6 -45.2 0.0 0.0 0.139 A:Q07812:0.139
 HOH
 7.901
 N
 O
5w5z 3 Q07812 98.14 3e-113 X-RAY
 2018-06-27 ALA C:65 A:96 4.0 0.035 H -67.9 -52.0 4.0 0.035 0.0
6l8v 1 Q07812 93.75 4e-48 NMR
 2020-11-11 ALA A:49 A:96 27.0 0.235 H -62.2 -40.4 27.0 0.235 0.0
ALA B:49 B:96 28.0 0.243 H -67.5 -42.8 28.0 0.243 0.0
4bdu 1 P42212,Q07812 97.37 4e-45 X-RAY
 2013-02-13 ALA A:277 A:1096 16.0 0.139 H -62.6 -51.1 16.0 0.139 0.0 HOH
 9.431
 N
 O
ALA B:277 B:1096 17.0 0.148 H -62.5 -51.7 17.0 0.148 0.0 HOH
 9.517
 C
 O
ALA C:277 C:1096 16.0 0.139 H -62.5 -51.7 NA NA NA
ALA D:277 D:1096 16.0 0.139 H -62.6 -51.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q07812-f1 1 Q07812 100.0 1e-140 ALA A:96 A:96 0.0 0.0 H -64.1 -46.1