Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 49464096 . C A CCDS12742.1:NM_138761.3:c.399atC>atA_NP_620116.1:p.133I>I Homo sapiens BCL2 associated X, apoptosis regulator (BAX), transcript variant alpha, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2lr1 1 Q07812 100.0 2e-140 NMR
 2012-12-05 ILE A:133 A:133 1.0 0.006 H -56.9 -50.1 1.0 0.006 0.0
4s0p 1 Q07812 99.48 3e-139 X-RAY
 2016-07-20 ILE A:133 A:133 45.0 0.257 H -38.8 -65.1 45.0 0.257 0.0
ILE B:133 B:133 45.0 0.257 H -31.9 -60.6 NA NA NA
6eb6 1 Q07812 99.48 4e-139 X-RAY
 2019-04-10 ILE A:133 A:133 6.0 0.034 H -62.0 -53.9 6.0 0.034 0.0 HOH
 6.440
 CD1
 O
4s0o 1 Q07812 99.48 6e-139 X-RAY
 2016-07-20 ILE A:133 A:133 47.0 0.269 H -57.8 -50.5 47.0 0.269 0.0 HOH
 3.526
 CB
 O
ILE B:133 B:133 39.0 0.223 H -60.0 -49.5 39.0 0.223 0.0 HOH
 4.157
 CB
 O
5w5x 3 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ILE C:133 A:133 33.0 0.189 H -78.8 -43.4 30.0 0.171 0.018 B:None:0.017
5w60 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ILE A:133 A:133 4.0 0.023 H -55.5 -54.5 4.0 0.023 0.0 HOH
 4.546
 CG2
 O
5w61 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 ILE A:133 A:133 70.0 0.4 H -48.5 -52.7 70.0 0.4 0.0 HOH
 7.261
 O
 O
5w62 1 Q07813 91.15 3e-125 X-RAY
 2018-06-27 ILE A:133 A:133 62.0 0.354 H -58.2 -48.8 62.0 0.354 0.0 HOH
 8.330
 CD1
 O
4bd2 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ILE A:133 A:133 97.0 0.554 H -66.4 -37.1 6.0 0.034 0.52 A:Q07812:0.52
 HOH
 3.554
 CG2
 O
4bd6 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ILE A:133 A:133 96.0 0.549 H -66.3 -37.0 10.0 0.057 0.492 A:Q07812:0.491
4bd7 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ILE A:133 A:133 88.0 0.503 H -67.6 -38.4 4.0 0.023 0.48 B:Q07812:0.48
ILE B:133 B:133 90.0 0.514 H -61.7 -39.7 36.0 0.206 0.308 A:Q07812:0.309
ILE C:133 C:133 91.0 0.52 H -53.0 -58.4 NA NA NA
ILE D:133 D:133 87.0 0.497 H -69.0 -48.7 NA NA NA
4bd8 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 ILE A:133 A:133 90.0 0.514 H -62.9 -43.2 8.0 0.046 0.468 B:Q07812:0.469
 EDO
HOH
 6.625
5.956
 C
N
 C1
O
ILE B:133 B:133 77.0 0.44 H -64.5 -42.8 29.0 0.166 0.274 A:Q07812:0.274
 HOH
 6.157
 O
 O
ILE C:133 C:133 100.0 0.571 H -64.9 -47.6 NA NA NA
ILE D:133 D:133 88.0 0.503 H -59.2 -46.3 NA NA NA
4zii 1 Q07812 98.82 1e-121 X-RAY
 2015-07-22 ILE A:133 A:133 91.0 0.52 H -60.2 -50.8 1.0 0.006 0.514 A:Q07812:0.514
 EDO
HOH
 7.164
7.074
 N
O
 O1
O
4zie 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ILE A:133 A:133 93.0 0.531 H -62.8 -43.9 22.0 0.126 0.405 A:Q07812:0.406
 HOH
 3.651
 CG2
 O
4zif 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ILE A:133 A:133 96.0 0.549 H -59.3 -45.6 14.0 0.08 0.469 A:Q07812:0.469
 HOH
 5.798
 CD1
 O
4zig 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 ILE A:133 A:133 94.0 0.537 H -62.3 -45.0 94.0 0.537 0.0 HOH
 7.148
 O
 O
4zih 1 Q07812 98.78 2e-116 X-RAY
 2015-07-22 ILE A:133 A:133 98.0 0.56 H -58.9 -45.2 21.0 0.12 0.44 A:Q07812:0.44
 HOH
 6.755
 O
 O
5w5z 3 Q07812 98.14 3e-113 X-RAY
 2018-06-27 ILE C:102 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q07812-f1 1 Q07812 100.0 1e-140 ILE A:133 A:133 6.0 0.034 H -61.3 -55.7