Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52714562 | . | A | C | CCDS12849.1:NM_014225.5:c.320aAg>aCg_NP_055040.2:p.107K>T | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | LYS | A:107 | A:107 | 41.0 | 0.205 | H | -52.6 | -39.5 | 41.0 | 0.205 | 0.0 | ||||||
2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | LYS | A:107 | A:107 | 47.0 | 0.235 | H | -52.3 | -37.0 | 47.0 | 0.235 | 0.0 |
HOH |
7.413 |
O |
O |
||
2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | LYS | A:107 | A:107 | 53.0 | 0.265 | H | -61.5 | -47.4 | NA | NA | NA | ||||||
LYS | D:107 | D:107 | 51.0 | 0.255 | H | -52.0 | -49.5 | 51.0 | 0.255 | 0.0 | |||||||||||||
3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | LYS | A:107 | A:107 | 45.0 | 0.225 | H | -54.4 | -43.5 | 45.0 | 0.225 | 0.0 |
HOH |
7.138 |
O |
O |
||
3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | LYS | A:107 | A:107 | 42.0 | 0.21 | H | -48.5 | -57.2 | 42.0 | 0.21 | 0.0 | ||||||
6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | LYS | A:107 | A:107 | 81.0 | 0.405 | H | -64.4 | -37.5 | 81.0 | 0.405 | 0.0 | ||||||
7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | LYS | J:107 | P:107 | 74.0 | 0.37 | H | -61.5 | -38.9 | 74.0 | 0.37 | 0.0 | ||||||
7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | LYS | A:107 | A:107 | 20.0 | NA | H | -61.3 | -33.0 | 20.0 | NA | NA | ||||||
7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | LYS | EA:107 | p:107 | 40.0 | 0.2 | H | -65.0 | -42.7 | 40.0 | 0.2 | 0.0 | ||||||
2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | LYS | A:107 | A:107 | 60.0 | 0.3 | H | -76.1 | -51.5 | 60.0 | 0.3 | 0.0 | ||||||
LYS | D:107 | D:107 | 43.0 | 0.215 | H | -70.8 | -44.6 | NA | NA | NA | |||||||||||||
2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | LYS | A:107 | A:107 | 43.0 | 0.215 | H | -68.5 | -42.0 | 43.0 | 0.215 | 0.0 | ||||||
LYS | B:107 | B:107 | 46.0 | 0.23 | H | -64.8 | -47.7 | NA | NA | NA | |||||||||||||
LYS | C:107 | C:107 | 50.0 | 0.25 | H | -65.2 | -33.7 | NA | NA | NA | |||||||||||||
LYS | D:107 | D:107 | 42.0 | 0.21 | H | -73.7 | -36.8 | NA | NA | NA | |||||||||||||
1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | LYS | A:106 | A:106 | 55.0 | 0.275 | H | -67.6 | -42.5 | 55.0 | 0.275 | 0.0 |
HOH |
4.612 |
NZ |
O |
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LYS | B:106 | B:106 | 40.0 | 0.2 | H | -68.8 | -41.1 | NA | NA | NA | |||||||||||||
3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | LYS | A:106 | A:107 | 53.0 | 0.265 | H | -59.8 | -44.0 | 53.0 | 0.265 | 0.0 |
HOH |
3.729 |
O |
O |
||
6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | LYS | A:108 | A:107 | 50.0 | 0.25 | H | -93.3 | -34.0 | 50.0 | 0.25 | 0.0 | ||||||
6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | LYS | A:105 | A:107 | 61.0 | 0.305 | H | -75.2 | -33.2 | 61.0 | 0.305 | 0.0 | ||||||
LYS | B:105 | B:107 | 53.0 | 0.265 | H | -69.2 | -36.1 | 53.0 | 0.265 | 0.0 | |||||||||||||
LYS | E:105 | E:107 | 51.0 | 0.255 | H | -65.9 | -36.9 | NA | NA | NA | |||||||||||||
LYS | F:105 | F:107 | 51.0 | 0.255 | H | -73.8 | -35.3 | NA | NA | NA | |||||||||||||
2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | LYS | A:100 | A:107 | 54.0 | 0.27 | H | -66.4 | -35.7 | 54.0 | 0.27 | 0.0 | ||||||
LYS | D:100 | D:107 | 51.0 | 0.255 | H | -74.1 | -42.6 | NA | NA | NA | |||||||||||||
2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | LYS | A:100 | A:107 | 53.0 | 0.265 | H | -69.8 | -38.0 | 53.0 | 0.265 | 0.0 | ||||||
LYS | D:100 | D:107 | 52.0 | 0.26 | H | -74.3 | -37.9 | NA | NA | NA | |||||||||||||
4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | LYS | A:102 | A:107 | 40.0 | 0.2 | H | -66.2 | -38.8 | 40.0 | 0.2 | 0.0 |
HOH |
3.384 |
CD |
O |
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LYS | D:102 | D:107 | 49.0 | 0.245 | H | -61.5 | -43.0 | NA | NA | NA | |||||||||||||
4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | LYS | A:102 | A:107 | 48.0 | 0.24 | H | -61.2 | -34.9 | 48.0 | 0.24 | 0.0 | ||||||
LYS | D:102 | D:107 | 40.0 | 0.2 | H | -60.9 | -44.4 | NA | NA | NA | |||||||||||||
3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | LYS | A:100 | A:107 | 47.0 | 0.235 | H | -57.6 | -60.2 | 47.0 | 0.235 | 0.0 | ||||||
LYS | D:100 | D:107 | 44.0 | 0.22 | H | -66.8 | -48.3 | NA | NA | NA | |||||||||||||
5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | LYS | A:103 | A:107 | 45.0 | 0.225 | H | -59.9 | -44.7 | 45.0 | 0.225 | 0.0 | ||||||
LYS | D:103 | D:107 | 47.0 | 0.235 | H | -75.2 | -29.9 | NA | NA | NA | |||||||||||||
LYS | G:103 | G:107 | 47.0 | 0.235 | H | -73.7 | -37.1 | NA | NA | NA | |||||||||||||
LYS | J:103 | J:107 | 49.0 | 0.245 | H | -63.6 | -29.1 | NA | NA | NA | |||||||||||||
2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | LYS | A:98 | A:107 | 60.0 | 0.3 | H | -53.4 | -58.2 | 60.0 | 0.3 | 0.0 | ||||||
LYS | B:98 | B:107 | 52.0 | 0.26 | H | -53.3 | -59.4 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | LYS | A:107 | A:107 | 39.0 | 0.195 | H | -65.7 | -39.1 | |
af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | LYS | A:119 | A:119 | 45.0 | 0.225 | H | -68.8 | -36.9 |