Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52715957 . C A CCDS12849.1:NM_014225.5:c.522tgC>tgA_NP_055040.2:p.174C>* Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 CYS A:174 A:174 8.0 0.059 H -70.6 -33.4 8.0 0.059 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 CYS A:174 A:174 7.0 0.052 H -76.0 -38.3 7.0 0.052 0.0 HOH
 9.905
 O
 O
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 CYS A:174 A:174 11.0 0.081 H -59.1 -33.2 NA NA NA
CYS D:174 D:174 11.0 0.081 H -63.5 -29.8 11.0 0.081 0.0
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 CYS A:174 A:174 9.0 0.067 H -74.8 -34.0 9.0 0.067 0.0
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 CYS A:174 A:174 9.0 0.067 H -72.7 -44.1 9.0 0.067 0.0
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 CYS A:174 A:174 6.0 0.044 H -69.3 -27.0 6.0 0.044 0.0
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 CYS J:174 P:174 13.0 0.096 T -81.9 13.1 13.0 0.096 0.0
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 CYS A:174 A:174 29.0 NA H -62.7 -32.7 29.0 NA NA
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 CYS EA:174 p:174 5.0 0.037 H -68.7 -18.9 5.0 0.037 0.0
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 CYS A:174 A:174 12.0 0.089 H -66.2 -20.6 12.0 0.089 0.0
CYS D:174 D:174 9.0 0.067 T -59.3 -8.0 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 CYS A:174 A:174 12.0 0.089 T -59.4 -16.5 12.0 0.089 0.0
CYS B:174 B:174 9.0 0.067 H -59.2 -23.0 NA NA NA
CYS C:174 C:174 12.0 0.089 H -71.4 -24.7 NA NA NA
CYS D:174 D:174 12.0 0.089 H -64.4 -25.3 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 CYS A:173 A:173 12.0 0.089 H -52.2 -25.5 12.0 0.089 0.0 HOH
 2.891
 O
 O
CYS B:173 B:173 8.0 0.059 H -61.4 -26.2 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 CYS A:173 A:174 14.0 0.104 H -57.5 -20.0 14.0 0.104 0.0 HOH
 2.736
 O
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 CYS A:175 A:174 9.0 0.067 H -73.8 -27.2 9.0 0.067 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 CYS A:172 A:174 13.0 0.096 H -63.1 -20.6 13.0 0.096 0.0
CYS B:172 B:174 12.0 0.089 H -74.0 -21.9 12.0 0.089 0.0
CYS E:172 E:174 8.0 0.059 H -74.9 -23.2 NA NA NA
CYS F:172 F:174 6.0 0.044 H -62.2 -18.6 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 CYS A:167 A:174 7.0 0.052 H -88.6 -27.2 7.0 0.052 0.0
CYS D:167 D:174 8.0 0.059 H -80.6 -34.6 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 CYS A:167 A:174 7.0 0.052 H -76.5 -31.5 7.0 0.052 0.0
CYS D:167 D:174 6.0 0.044 H -68.6 -35.5 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 CYS A:169 A:174 12.0 0.089 H -58.6 -27.2 12.0 0.089 0.0 PEG
HOH
 8.415
2.750
 N
O
 O4
O
CYS D:169 D:174 14.0 0.104 H -60.9 -24.3 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 CYS A:169 A:174 8.0 0.059 H -61.0 -35.3 8.0 0.059 0.0
CYS D:169 D:174 11.0 0.081 H -56.6 -32.0 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 CYS A:167 A:174 8.0 0.059 T -67.1 -16.4 8.0 0.059 0.0
CYS D:167 D:174 11.0 0.081 H -72.6 -19.3 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 CYS A:170 A:174 3.0 0.022 H -68.7 -16.1 3.0 0.022 0.0
CYS D:170 D:174 7.0 0.052 H -77.2 -39.7 NA NA NA
CYS G:170 G:174 7.0 0.052 H -63.6 -26.3 NA NA NA
CYS J:170 J:174 7.0 0.052 H -66.4 -19.6 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 CYS A:165 A:174 9.0 0.067 T -61.3 -6.2 9.0 0.067 0.0
CYS B:165 B:174 13.0 0.096 H -70.6 -10.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 CYS A:174 A:174 12.0 0.089 H -64.8 -26.9
af-p30154-f1 1 P30154 86.4 0.0 CYS A:186 A:186 4.0 0.03 H -65.1 -26.5