Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52715967 | . | A | C | CCDS12849.1:NM_014225.5:c.532Acc>Ccc_NP_055040.2:p.178T>P | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | THR | A:178 | A:178 | 45.0 | 0.321 | S | -107.7 | 144.4 | 45.0 | 0.321 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | THR | A:178 | A:178 | 48.0 | 0.343 | S | -85.4 | 136.9 | 48.0 | 0.343 | 0.0 |
HOH |
6.242 |
C |
O |
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| 2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | THR | A:178 | A:178 | 30.0 | 0.214 | -125.7 | 138.1 | NA | NA | NA | |||||||
| THR | D:178 | D:178 | 29.0 | 0.207 | -126.7 | 127.3 | 16.0 | 0.114 | 0.093 |
E:Q13362:0.093 |
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| 3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | THR | A:178 | A:178 | 49.0 | 0.35 | S | -99.6 | 129.7 | 49.0 | 0.35 | 0.0 | ||||||
| 3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | THR | A:178 | A:178 | 48.0 | 0.343 | S | -109.2 | 127.2 | 48.0 | 0.343 | 0.0 | ||||||
| 6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | THR | A:178 | A:178 | 32.0 | 0.229 | S | -119.3 | 151.9 | 17.0 | 0.121 | 0.108 |
B:Q15172:0.107 |
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| 7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | THR | J:178 | P:178 | 47.0 | 0.336 | S | -101.0 | 142.8 | 47.0 | 0.336 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | THR | A:178 | A:178 | 6.0 | NA | -123.2 | 89.9 | 6.0 | NA | NA | |||||||
| 7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | THR | EA:178 | p:178 | 34.0 | 0.243 | S | -73.5 | 141.0 | 34.0 | 0.243 | 0.0 | ||||||
| 2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | THR | A:178 | A:178 | 20.0 | 0.143 | S | -114.1 | 143.4 | 0.0 | 0.0 | 0.143 |
B:Q13362:0.143 |
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| THR | D:178 | D:178 | 31.0 | 0.221 | S | -115.1 | 133.3 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | THR | A:178 | A:178 | 33.0 | 0.236 | S | -114.5 | 119.1 | 0.0 | 0.0 | 0.236 |
E:Q9W9P1:0.236 |
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| THR | B:178 | B:178 | 30.0 | 0.214 | S | -101.6 | 138.9 | NA | NA | NA | |||||||||||||
| THR | C:178 | C:178 | 31.0 | 0.221 | S | -121.4 | 127.2 | NA | NA | NA | |||||||||||||
| THR | D:178 | D:178 | 33.0 | 0.236 | S | -115.3 | 146.9 | NA | NA | NA | |||||||||||||
| 1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | THR | A:177 | A:177 | 32.0 | 0.229 | -80.8 | 120.2 | 32.0 | 0.229 | 0.0 |
HOH |
3.135 |
OG1 |
O |
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| THR | B:177 | B:177 | 31.0 | 0.221 | S | -84.1 | 120.5 | NA | NA | NA | |||||||||||||
| 3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | THR | A:177 | A:178 | 30.0 | 0.214 | S | -95.7 | 135.7 | 5.0 | 0.036 | 0.178 |
B:Q13362:0.179 |
HOH |
3.767 |
CG2 |
O |
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| 6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | THR | A:179 | A:178 | 41.0 | 0.293 | S | -93.0 | 148.1 | 41.0 | 0.293 | 0.0 | ||||||
| 6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | THR | A:176 | A:178 | 26.0 | 0.186 | -89.3 | 128.7 | 26.0 | 0.186 | 0.0 | |||||||
| THR | B:176 | B:178 | 42.0 | 0.3 | S | -81.2 | 136.4 | 42.0 | 0.3 | 0.0 | |||||||||||||
| THR | E:176 | E:178 | 34.0 | 0.243 | S | -80.6 | 134.4 | NA | NA | NA | |||||||||||||
| THR | F:176 | F:178 | 30.0 | 0.214 | S | -91.1 | 130.8 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | THR | A:171 | A:178 | 28.0 | 0.2 | -103.2 | 115.8 | 20.0 | 0.143 | 0.057 |
B:Q13362:0.057 |
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| THR | D:171 | D:178 | 27.0 | 0.193 | -99.0 | 124.2 | NA | NA | NA | ||||||||||||||
| 2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | THR | A:171 | A:178 | 26.0 | 0.186 | S | -108.5 | 123.6 | 18.0 | 0.129 | 0.057 |
B:Q13362:0.057 |
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| THR | D:171 | D:178 | 24.0 | 0.171 | S | -120.2 | 134.7 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | THR | A:173 | A:178 | 34.0 | 0.243 | S | -100.5 | 123.0 | 0.0 | 0.0 | 0.243 |
B:Q9Y5P8+Q99741:0.243 |
PEG HOH |
6.284 4.043 |
OG1 OG1 |
O1 O |
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| THR | D:173 | D:178 | 38.0 | 0.271 | S | -104.4 | 116.5 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | THR | A:173 | A:178 | 36.0 | 0.257 | S | -138.8 | 119.3 | 0.0 | 0.0 | 0.257 |
B:Q9Y5P8+Q99741:0.257 |
HOH |
5.293 |
OG1 |
O |
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| THR | D:173 | D:178 | 37.0 | 0.264 | S | -98.2 | 124.9 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | THR | A:171 | A:178 | 30.0 | 0.214 | S | -97.2 | 131.5 | 7.0 | 0.05 | 0.164 |
B:P63151:0.164 |
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| THR | D:171 | D:178 | 34.0 | 0.243 | S | -94.4 | 140.7 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | THR | A:174 | A:178 | 34.0 | 0.243 | S | -64.9 | 138.4 | 14.0 | 0.1 | 0.143 |
B:Q8BH58:0.143 |
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| THR | D:174 | D:178 | 30.0 | 0.214 | -112.1 | 136.8 | NA | NA | NA | ||||||||||||||
| THR | G:174 | G:178 | 18.0 | 0.129 | -102.8 | 139.2 | NA | NA | NA | ||||||||||||||
| THR | J:174 | J:178 | 25.0 | 0.179 | -103.4 | 117.0 | NA | NA | NA | ||||||||||||||
| 2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | THR | A:169 | A:178 | 35.0 | 0.25 | S | -90.2 | 115.9 | 13.0 | 0.093 | 0.157 |
C:P03081:0.157 |
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| THR | B:169 | B:178 | 31.0 | 0.221 | S | -97.0 | 135.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | THR | A:178 | A:178 | 33.0 | 0.236 | S | -92.5 | 117.4 | |
| af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | THR | A:190 | A:190 | 38.0 | 0.271 | S | -85.2 | 117.7 | |