Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52715974 . T A CCDS12849.1:NM_014225.5:c.539aTg>aAg_NP_055040.2:p.180M>K Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 MET A:180 A:180 82.0 0.443 H -53.8 -45.4 82.0 0.443 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 MET A:180 A:180 82.0 0.443 H -54.1 -40.6 82.0 0.443 0.0 HOH
 7.836
 N
 O
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 MET A:180 A:180 61.0 0.33 H -51.2 -53.7 NA NA NA
MET D:180 D:180 66.0 0.357 H -54.0 -41.3 3.0 0.016 0.341 E:Q13362:0.341
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 MET A:180 A:180 60.0 0.324 H -60.4 -50.9 60.0 0.324 0.0
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 MET A:180 A:180 62.0 0.335 H -56.7 -49.5 62.0 0.335 0.0
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 MET A:180 A:180 61.0 0.33 H -65.8 -47.5 12.0 0.065 0.265 B:Q15172:0.265
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 MSE J:180 P:180 89.0 0.481 H -62.2 -21.6 89.0 0.481 0.0
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 MET A:180 A:180 52.0 NA H -64.8 -56.7 52.0 NA NA
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 MET EA:180 p:180 49.0 0.265 H -73.5 -23.5 49.0 0.265 0.0
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 MET A:180 A:180 62.0 0.335 H -65.3 -53.1 13.0 0.07 0.265 B:Q13362:0.265
MET D:180 D:180 69.0 0.373 H -49.1 -47.2 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 MET A:180 A:180 84.0 0.454 H -56.1 -33.8 15.0 0.081 0.373 E:Q9W9P1:0.373
 ZN
 9.724
 CE
 ZN
MET B:180 B:180 68.0 0.368 H -51.9 -44.9 NA NA NA
MET C:180 C:180 72.0 0.389 H -51.0 -42.1 NA NA NA
MET D:180 D:180 69.0 0.373 H -29.4 -49.1 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 MET A:179 A:179 78.0 0.422 H -55.2 -36.9 78.0 0.422 0.0 HOH
 2.811
 O
 O
MET B:179 B:179 76.0 0.411 H -56.7 -36.8 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 MET A:179 A:180 66.0 0.357 H -61.3 -45.4 2.0 0.011 0.346 B:Q13362:0.346
 HOH
 3.248
 SD
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 MET A:181 A:180 80.0 0.432 H -62.5 -39.7 80.0 0.432 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 MET A:178 A:180 68.0 0.368 H -65.5 -28.2 68.0 0.368 0.0
MET B:178 B:180 74.0 0.4 H -66.5 -45.7 74.0 0.4 0.0
MET E:178 E:180 76.0 0.411 H -63.8 -45.0 NA NA NA
MET F:178 F:180 69.0 0.373 H -65.8 -26.9 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 MSE A:173 A:180 66.0 0.357 H -45.1 -46.2 4.0 0.022 0.335 B:Q13362:0.335
MSE D:173 D:180 66.0 0.357 H -32.9 -49.6 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 MSE A:173 A:180 65.0 0.351 H -48.3 -51.9 4.0 0.022 0.329 B:Q13362:0.33
MSE D:173 D:180 63.0 0.341 H -35.7 -56.3 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 MET A:175 A:180 80.0 0.432 H -57.6 -38.0 0.0 0.0 0.432 B:Q9Y5P8+Q99741:0.432
 CA
HOH
 8.097
5.614
 CG
SD
 CA
O
MET D:175 D:180 81.0 0.438 H -52.1 -38.8 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 MSE A:175 A:180 84.0 0.454 H -61.3 -31.6 4.0 0.022 0.432 B:Q9Y5P8+Q99741:0.432
 CA
HOH
 8.331
6.102
 CG
CG
 CA
O
MSE D:175 D:180 84.0 0.454 H -56.8 -29.7 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 MET A:173 A:180 45.0 0.243 H -59.6 -65.8 30.0 0.162 0.081 B:P63151:0.081
MET D:173 D:180 44.0 0.238 H -59.6 -60.2 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 MSE A:176 A:180 74.0 0.4 H -58.5 -54.0 11.0 0.059 0.341 B:Q8BH58:0.341
MSE D:176 D:180 87.0 0.47 H -54.0 -41.6 NA NA NA
MSE G:176 G:180 89.0 0.481 H -58.6 -51.0 NA NA NA
MSE J:176 J:180 75.0 0.405 H -71.4 -8.2 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 MET A:171 A:180 57.0 0.308 H -41.8 -55.1 13.0 0.07 0.238 C:P03081:0.238
MET B:171 B:180 61.0 0.33 H -46.6 -63.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 MET A:180 A:180 67.0 0.362 H -63.6 -32.8
af-p30154-f1 1 P30154 86.4 0.0 MET A:192 A:192 99.0 0.535 H -62.9 -36.5