Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52716212 . C A CCDS12849.1:NM_014225.5:c.656tCg>tAg_NP_055040.2:p.219S>* Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 SER A:219 A:219 21.0 0.183 H -71.3 -25.1 21.0 0.183 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 SER A:219 A:219 26.0 0.226 H -71.5 -18.5 26.0 0.226 0.0 HOH
 2.872
 O
 O
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 SER A:219 A:219 34.0 0.296 H -56.2 -14.1 NA NA NA
SER D:219 D:219 35.0 0.304 H -67.6 -5.5 7.0 0.061 0.243 E:Q13362:0.243
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 SER A:219 A:219 25.0 0.217 H -62.2 -23.2 25.0 0.217 0.0 HOH
 4.779
 N
 O
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 SER A:219 A:219 26.0 0.226 H -58.5 -28.4 26.0 0.226 0.0 HOH
 4.927
 N
 O
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 SER A:219 A:219 32.0 0.278 H -60.3 -43.0 16.0 0.139 0.139 B:Q15172:0.139
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 SER J:219 P:219 19.0 0.165 T -70.4 -18.6 19.0 0.165 0.0
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 SER A:219 A:219 76.0 NA H -61.2 -31.8 76.0 NA NA
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 SER EA:219 p:219 43.0 0.374 H -65.6 -38.0 43.0 0.374 0.0
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 SER A:219 A:219 29.0 0.252 H -79.9 -4.4 5.0 0.043 0.209 B:Q13362:0.209
SER D:219 D:219 33.0 0.287 H -65.5 -17.3 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 SER A:219 A:219 12.0 0.104 H -57.0 -31.5 7.0 0.061 0.043 E:Q9W9P1:0.043
SER B:219 B:219 14.0 0.122 H -54.7 -26.2 NA NA NA
SER C:219 C:219 17.0 0.148 H -55.1 -29.2 NA NA NA
SER D:219 D:219 9.0 0.078 H -54.6 -16.4 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 SER A:218 A:218 34.0 0.296 H -57.2 -21.7 34.0 0.296 0.0 HOH
 2.858
 O
 O
SER B:218 B:218 32.0 0.278 H -56.7 -17.3 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 SER A:218 A:219 30.0 0.261 H -74.2 -29.9 5.0 0.043 0.218 B:Q13362:0.217
 HOH
 6.738
 OG
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 SER A:220 A:219 22.0 0.191 H -69.8 -26.2 22.0 0.191 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 SER A:217 A:219 46.0 0.4 H -62.3 -47.8 46.0 0.4 0.0
SER B:217 B:219 28.0 0.243 H -56.0 -35.3 28.0 0.243 0.0 TME
 9.632
 CA
 C1
SER E:217 E:219 36.0 0.313 H -53.9 -35.6 NA NA NA
SER F:217 F:219 28.0 0.243 H -62.7 -46.9 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 SER A:212 A:219 42.0 0.365 H -63.7 4.4 15.0 0.13 0.235 B:Q13362:0.235
SER D:212 D:219 39.0 0.339 H -74.9 13.4 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 SER A:212 A:219 38.0 0.33 H -66.7 -9.8 11.0 0.096 0.234 B:Q13362:0.235
SER D:212 D:219 39.0 0.339 H -78.5 7.4 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 SER A:214 A:219 48.0 0.417 H -55.4 -36.5 13.0 0.113 0.304 B:Q9Y5P8+Q99741:0.304
 CA
HOH
 7.429
2.736
 OG
O
 CA
O
SER D:214 D:219 39.0 0.339 H -48.7 -44.3 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 SER A:214 A:219 45.0 0.391 H -41.2 -42.0 13.0 0.113 0.278 B:Q9Y5P8+Q99741:0.278
 CA
HOH
 7.266
4.942
 OG
N
 CA
O
SER D:214 D:219 38.0 0.33 H -48.9 -46.4 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 SER A:212 A:219 42.0 0.365 H -53.2 -41.3 18.0 0.157 0.208 B:P63151:0.209
SER D:212 D:219 24.0 0.209 H -63.5 -25.2 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 SER A:215 A:219 39.0 0.339 H -59.6 -27.0 10.0 0.087 0.252 B:Q8BH58:0.252
SER D:215 D:219 40.0 0.348 H -49.8 -32.1 NA NA NA
SER G:215 G:219 51.0 0.443 H -76.8 -9.2 NA NA NA
SER J:215 J:219 34.0 0.296 H -64.1 -41.2 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 SER A:210 A:219 40.0 0.348 H -65.8 -0.9 9.0 0.078 0.27 C:P03081:0.27
SER B:210 B:219 37.0 0.322 H -46.2 -24.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 SER A:219 A:219 30.0 0.261 H -61.4 -23.5
af-p30154-f1 1 P30154 86.4 0.0 SER A:231 A:231 36.0 0.313 H -60.6 -24.8