Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52716329 . G A CCDS12849.1:NM_014225.5:c.773cGc>cAc_NP_055040.2:p.258R>H Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ARG A:258 A:258 104.0 0.462 H -60.6 -46.8 104.0 0.462 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ARG A:258 A:258 108.0 0.48 H -69.3 -46.7 108.0 0.48 0.0 HOH
 5.765
 NH2
 O
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:258 A:258 119.0 0.529 H -60.3 -40.1 NA NA NA
ARG D:258 D:258 124.0 0.551 H -62.0 -36.8 86.0 0.382 0.169 E:Q13362:0.169
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ARG A:258 A:258 109.0 0.484 H -63.7 -39.0 109.0 0.484 0.0 HOH
 5.927
 NH1
 O
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ARG A:258 A:258 111.0 0.493 H -64.1 -46.0 111.0 0.493 0.0 HOH
 5.544
 NH1
 O
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 ARG A:258 A:258 83.0 0.369 H -50.3 -41.4 83.0 0.369 0.0
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 ARG J:258 P:258 103.0 0.458 H -69.9 -49.2 85.0 0.378 0.08 E:Q9UL03:0.08
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 ARG A:258 A:258 72.0 NA H -59.9 -59.4 72.0 NA NA
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 ARG EA:258 p:258 120.0 0.533 H -63.7 -47.8 62.0 0.276 0.257 Z:Q9UL03:0.258
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 ARG A:258 A:258 125.0 0.556 H -63.7 -17.2 79.0 0.351 0.205 B:Q13362:0.204
ARG D:258 D:258 114.0 0.507 H -55.9 -47.1 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 ARG A:258 A:258 101.0 0.449 H -52.1 -45.0 36.0 0.16 0.289 E:Q9W9P1:0.289
ARG B:258 B:258 105.0 0.467 H -67.2 -48.5 NA NA NA
ARG C:258 C:258 103.0 0.458 H -62.1 -34.6 NA NA NA
ARG D:258 D:258 98.0 0.436 H -55.4 -27.4 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 ARG A:257 A:257 118.0 0.524 H -67.3 -33.9 118.0 0.524 0.0 HOH
 3.504
 CD
 O
ARG B:257 B:257 110.0 0.489 H -59.7 -35.3 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 ARG A:257 A:258 117.0 0.52 H -65.6 -35.0 67.0 0.298 0.222 B:Q13362:0.222
 HOH
 5.769
 N
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 ARG A:259 A:258 134.0 0.596 H -71.9 -30.9 134.0 0.596 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 ARG A:256 A:258 135.0 0.6 H -65.1 -35.6 135.0 0.6 0.0
ARG B:256 B:258 123.0 0.547 H -64.5 -41.2 123.0 0.547 0.0 TME
 4.802
 NH1
 C1
ARG E:256 E:258 119.0 0.529 H -61.7 -38.2 NA NA NA
ARG F:256 F:258 121.0 0.538 H -74.3 -33.5 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:251 A:258 125.0 0.556 H -53.9 -37.7 88.0 0.391 0.165 B:Q13362:0.164
ARG D:251 D:258 127.0 0.564 H -55.4 -30.6 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:251 A:258 122.0 0.542 H -59.3 -50.3 82.0 0.364 0.178 B:Q13362:0.178
ARG D:251 D:258 123.0 0.547 H -59.4 -52.9 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ARG A:253 A:258 91.0 0.404 H -62.7 -38.4 33.0 0.147 0.257 B:Q9Y5P8+Q99741:0.258
 PEG
CA
HOH
 9.831
7.705
4.108
 N
NH2
NH2
 O1
CA
O
ARG D:253 D:258 92.0 0.409 H -70.0 -36.4 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ARG A:253 A:258 85.0 0.378 H -58.8 -30.7 35.0 0.156 0.222 B:Q9Y5P8+Q99741:0.222
 CA
HOH
 8.105
5.801
 NH2
NH1
 CA
O
ARG D:253 D:258 95.0 0.422 H -63.4 -27.6 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 ARG A:251 A:258 158.0 0.702 H -75.7 -47.4 154.0 0.684 0.018 B:P63151:0.018
ARG D:251 D:258 106.0 0.471 H -76.4 -57.6 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 ARG A:254 A:258 152.0 0.676 H -52.2 -32.4 152.0 0.676 0.0
ARG D:254 D:258 149.0 0.662 H -63.5 -44.4 NA NA NA
ARG G:254 G:258 151.0 0.671 H -62.9 -26.8 NA NA NA
ARG J:254 J:258 143.0 0.636 H -69.0 -29.2 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 ARG A:249 A:258 124.0 0.551 H -47.8 -38.3 74.0 0.329 0.222 C:P03081:0.222
ARG B:249 B:258 127.0 0.564 H -55.9 -45.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 ARG A:258 A:258 103.0 0.458 H -66.5 -33.6
af-p30154-f1 1 P30154 86.4 0.0 ARG A:270 A:270 124.0 0.551 H -64.5 -34.6