Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52719069 | . | A | C | CCDS12849.1:NM_014225.5:c.845gAc>gCc_NP_055040.2:p.282D>A | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | ASP | A:282 | A:282 | 25.0 | 0.167 | I | -94.8 | -43.9 | 25.0 | 0.167 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | ASP | A:282 | A:282 | 29.0 | 0.193 | I | -92.9 | -49.5 | 29.0 | 0.193 | 0.0 |
HOH |
7.744 |
OD2 |
O |
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| 2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ASP | A:282 | A:282 | 34.0 | 0.227 | I | -100.5 | -44.5 | NA | NA | NA | ||||||
| ASP | D:282 | D:282 | 33.0 | 0.22 | I | -95.0 | -48.7 | 33.0 | 0.22 | 0.0 | |||||||||||||
| 3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | ASP | A:282 | A:282 | 25.0 | 0.167 | I | -88.3 | -43.9 | 25.0 | 0.167 | 0.0 |
HOH |
9.174 |
N |
O |
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| 3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | ASP | A:282 | A:282 | 27.0 | 0.18 | I | -85.8 | -35.3 | 27.0 | 0.18 | 0.0 | ||||||
| 6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | ASP | A:282 | A:282 | 71.0 | 0.473 | I | -114.3 | -43.0 | 71.0 | 0.473 | 0.0 | ||||||
| 7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | ASP | J:282 | P:282 | 44.0 | 0.293 | T | -133.3 | 2.3 | 44.0 | 0.293 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | ASP | A:282 | A:282 | 79.0 | NA | T | -64.8 | -36.9 | 79.0 | NA | NA | ||||||
| 7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | ASP | EA:282 | p:282 | 39.0 | 0.26 | I | -119.3 | -33.2 | 39.0 | 0.26 | 0.0 | ||||||
| 2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | ASP | A:282 | A:282 | 35.0 | 0.233 | I | -116.4 | -42.6 | 35.0 | 0.233 | 0.0 | ||||||
| ASP | D:282 | D:282 | 46.0 | 0.307 | I | -121.5 | -30.9 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | ASP | A:282 | A:282 | 34.0 | 0.227 | I | -107.6 | -40.9 | 34.0 | 0.227 | 0.0 | ||||||
| ASP | B:282 | B:282 | 34.0 | 0.227 | I | -114.7 | -40.8 | NA | NA | NA | |||||||||||||
| ASP | C:282 | C:282 | 33.0 | 0.22 | I | -122.8 | -42.0 | NA | NA | NA | |||||||||||||
| ASP | D:282 | D:282 | 33.0 | 0.22 | I | -97.7 | -49.6 | NA | NA | NA | |||||||||||||
| 1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | ASP | A:281 | A:281 | 28.0 | 0.187 | I | -105.7 | -51.1 | 28.0 | 0.187 | 0.0 |
HOH |
3.150 |
O |
O |
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| ASP | B:281 | B:281 | 32.0 | 0.213 | I | -107.0 | -42.9 | NA | NA | NA | |||||||||||||
| 3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | ASP | A:281 | A:282 | 22.0 | 0.147 | I | -97.8 | -43.4 | 22.0 | 0.147 | 0.0 | ||||||
| 6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | ASP | A:283 | A:282 | 35.0 | 0.233 | I | -119.1 | -41.3 | 35.0 | 0.233 | 0.0 | ||||||
| 6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | ASP | A:280 | A:282 | 42.0 | 0.28 | I | -119.0 | -36.3 | 42.0 | 0.28 | 0.0 | ||||||
| ASP | B:280 | B:282 | 20.0 | 0.133 | I | -104.0 | -19.5 | 20.0 | 0.133 | 0.0 | |||||||||||||
| ASP | E:280 | E:282 | 52.0 | 0.347 | I | -100.6 | -25.0 | NA | NA | NA | |||||||||||||
| ASP | F:280 | F:282 | 37.0 | 0.247 | I | -120.2 | -32.5 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ASP | A:275 | A:282 | 38.0 | 0.253 | I | -114.3 | -46.2 | 38.0 | 0.253 | 0.0 | ||||||
| ASP | D:275 | D:282 | 36.0 | 0.24 | I | -110.2 | -46.4 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ASP | A:275 | A:282 | 28.0 | 0.187 | I | -118.3 | -51.7 | 28.0 | 0.187 | 0.0 | ||||||
| ASP | D:275 | D:282 | 31.0 | 0.207 | I | -115.4 | -48.6 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | ASP | A:277 | A:282 | 31.0 | 0.207 | I | -111.3 | -48.6 | 31.0 | 0.207 | 0.0 |
HOH |
6.469 |
N |
O |
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| ASP | D:277 | D:282 | 27.0 | 0.18 | I | -106.5 | -40.4 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | ASP | A:277 | A:282 | 29.0 | 0.193 | I | -106.5 | -45.2 | 29.0 | 0.193 | 0.0 | ||||||
| ASP | D:277 | D:282 | 26.0 | 0.173 | I | -102.1 | -61.8 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | ASP | A:275 | A:282 | 37.0 | 0.247 | I | -103.1 | -39.5 | 37.0 | 0.247 | 0.0 | ||||||
| ASP | D:275 | D:282 | 29.0 | 0.193 | I | -105.5 | -46.8 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | ASP | A:278 | A:282 | 22.0 | 0.147 | I | -134.7 | -30.8 | 22.0 | 0.147 | 0.0 | ||||||
| ASP | D:278 | D:282 | 33.0 | 0.22 | I | -117.4 | -50.4 | NA | NA | NA | |||||||||||||
| ASP | G:278 | G:282 | 30.0 | 0.2 | I | -122.4 | -41.7 | NA | NA | NA | |||||||||||||
| ASP | J:278 | J:282 | 33.0 | 0.22 | I | -128.8 | -15.8 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | ASP | A:273 | A:282 | 27.0 | 0.18 | I | -121.6 | -56.9 | 27.0 | 0.18 | 0.0 | ||||||
| ASP | B:273 | B:282 | 28.0 | 0.187 | I | -118.4 | -54.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | ASP | A:282 | A:282 | 29.0 | 0.193 | I | -119.0 | -45.8 | |
| af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | ASP | A:294 | A:294 | 23.0 | 0.153 | I | -128.4 | -43.9 | |