Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52719913 . T A CCDS12849.1:NM_014225.5:c.1125gaT>gaA_NP_055040.2:p.375D>E Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ASP A:375 A:375 24.0 0.16 -87.5 164.2 24.0 0.16 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ASP A:375 A:375 23.0 0.153 -90.4 168.5 23.0 0.153 0.0
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ASP A:375 A:375 20.0 0.133 -61.9 161.8 NA NA NA
ASP D:375 D:375 21.0 0.14 -59.2 168.6 21.0 0.14 0.0
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ASP A:375 A:375 24.0 0.16 -91.6 163.3 24.0 0.16 0.0
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ASP A:375 A:375 21.0 0.14 -96.6 159.5 21.0 0.14 0.0
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 ASP A:375 A:375 27.0 0.18 S -71.3 166.2 27.0 0.18 0.0
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 ASP J:375 P:375 33.0 0.22 -109.3 173.1 33.0 0.22 0.0
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 ASP A:375 A:375 91.0 NA T -130.0 82.3 91.0 NA NA
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 ASP EA:375 p:375 24.0 0.16 -69.3 145.3 24.0 0.16 0.0
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 ASP A:375 A:375 23.0 0.153 -73.0 152.5 23.0 0.153 0.0
ASP D:375 D:375 18.0 0.12 -63.0 157.6 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 ASP A:375 A:375 31.0 0.207 -60.6 135.2 31.0 0.207 0.0
ASP B:375 B:375 31.0 0.207 -76.8 142.7 NA NA NA
ASP C:375 C:375 25.0 0.167 -123.8 157.0 NA NA NA
ASP D:375 D:375 11.0 0.073 -52.8 151.7 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 ASP A:374 A:374 25.0 0.167 -64.4 160.0 25.0 0.167 0.0 HOH
 2.597
 OD1
 O
ASP B:374 B:374 27.0 0.18 -110.2 135.6 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 ASP A:374 A:375 19.0 0.127 -61.7 150.7 19.0 0.127 0.0 HOH
 4.024
 OD1
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 ASP A:376 A:375 26.0 0.173 -87.6 144.6 26.0 0.173 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 ASP A:373 A:375 12.0 0.08 S -68.5 150.7 12.0 0.08 0.0
ASP B:373 B:375 27.0 0.18 -63.2 144.8 27.0 0.18 0.0
ASP E:373 E:375 25.0 0.167 -63.0 145.0 NA NA NA
ASP F:373 F:375 25.0 0.167 S -68.1 144.5 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ASP A:368 A:375 24.0 0.16 -54.5 134.9 24.0 0.16 0.0
ASP D:368 D:375 20.0 0.133 -48.6 139.8 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ASP A:368 A:375 20.0 0.133 -61.9 160.9 20.0 0.133 0.0
ASP D:368 D:375 18.0 0.12 -62.8 163.5 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ASP A:370 A:375 22.0 0.147 -67.0 142.7 22.0 0.147 0.0 PEG
HOH
 5.642
2.726
 O
OD2
 C4
O
ASP D:370 D:375 11.0 0.073 -66.3 139.2 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ASP A:370 A:375 21.0 0.14 -72.2 146.2 21.0 0.14 0.0
ASP D:370 D:375 24.0 0.16 -71.6 153.2 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 ASP A:368 A:375 20.0 0.133 -105.4 144.5 20.0 0.133 0.0
ASP D:368 D:375 22.0 0.147 -111.0 141.0 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 ASP A:371 A:375 29.0 0.193 -63.5 159.3 29.0 0.193 0.0
ASP D:371 D:375 27.0 0.18 -74.6 128.8 NA NA NA
ASP G:371 G:375 13.0 0.087 -102.5 152.0 NA NA NA
ASP J:371 J:375 20.0 0.133 S -79.4 -168.7 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 ASP A:366 A:375 23.0 0.153 -47.8 151.9 23.0 0.153 0.0
ASP B:366 B:375 29.0 0.193 -48.9 162.4 NA NA NA
3c5w 1 P30153 88.39 1e-141 X-RAY
 2008-04-15 ASN A:18 A:22 37.0 0.231 -62.4 163.8 37.0 0.231 0.0
4lac 2 ? 85.71 9e-137 X-RAY
 2013-10-09 ASN B:44 A:375 47.0 0.294 -72.4 141.4 47.0 0.294 0.0 HOH
 5.941
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 ASP A:375 A:375 18.0 0.12 -67.2 144.4
af-p30154-f1 1 P30154 86.4 0.0 ASP A:387 A:387 19.0 0.127 -67.4 144.0