Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52724339 | . | G | A | CCDS12849.1:NM_014225.5:c.1471Gga>Aga_NP_055040.2:p.491G>R | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | GLY | A:491 | A:491 | 66.0 | 0.88 | G | -90.4 | -16.0 | 66.0 | 0.88 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | GLY | A:491 | A:491 | 64.0 | 0.853 | G | -92.5 | 4.7 | 64.0 | 0.853 | 0.0 | ||||||
| 2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | GLY | A:491 | A:491 | 65.0 | 0.867 | S | -106.2 | 53.8 | NA | NA | NA | ||||||
| GLY | D:491 | D:491 | 66.0 | 0.88 | S | -109.1 | 53.3 | 66.0 | 0.88 | 0.0 | |||||||||||||
| 3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | GLY | A:491 | A:491 | 69.0 | 0.92 | G | -86.1 | -6.7 | 69.0 | 0.92 | 0.0 | ||||||
| 3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | GLY | A:491 | A:491 | 64.0 | 0.853 | G | -80.7 | -23.0 | 64.0 | 0.853 | 0.0 | ||||||
| 6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | GLY | A:491 | A:491 | 69.0 | 0.92 | G | -99.6 | 21.5 | 69.0 | 0.92 | 0.0 | ||||||
| 7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | GLY | J:491 | P:491 | 65.0 | 0.867 | T | -144.0 | 7.6 | 65.0 | 0.867 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | GLY | A:491 | A:491 | 54.0 | 0.72 | -129.8 | 116.3 | 54.0 | 0.72 | 0.0 | |||||||
| 7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | GLY | EA:491 | p:491 | 56.0 | 0.747 | S | -84.4 | 8.3 | 56.0 | 0.747 | 0.0 | ||||||
| 2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | GLY | A:491 | A:491 | 61.0 | 0.813 | G | -85.2 | -22.8 | 61.0 | 0.813 | 0.0 | ||||||
| GLY | D:491 | D:491 | 40.0 | 0.533 | -46.0 | 90.8 | NA | NA | NA | ||||||||||||||
| 2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | GLY | A:491 | A:491 | 65.0 | 0.867 | T | -106.1 | 0.3 | 65.0 | 0.867 | 0.0 | ||||||
| GLY | B:491 | B:491 | 60.0 | 0.8 | G | -108.5 | -0.4 | NA | NA | NA | |||||||||||||
| GLY | C:491 | C:491 | 64.0 | 0.853 | G | -129.8 | -5.5 | NA | NA | NA | |||||||||||||
| GLY | D:491 | D:491 | 76.0 | 1.0 | S | -68.1 | 85.0 | NA | NA | NA | |||||||||||||
| 1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | GLY | A:490 | A:490 | 58.0 | 0.773 | T | -74.6 | -59.0 | 58.0 | 0.773 | 0.0 |
HOH |
3.429 |
O |
O |
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| GLY | B:490 | B:490 | 66.0 | 0.88 | T | -104.3 | 32.7 | NA | NA | NA | |||||||||||||
| 3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | GLY | A:490 | A:491 | 63.0 | 0.84 | G | -112.9 | 12.0 | 63.0 | 0.84 | 0.0 |
HOH |
5.947 |
N |
O |
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| 6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | GLY | A:492 | A:491 | 66.0 | 0.88 | G | -103.8 | 19.9 | 66.0 | 0.88 | 0.0 | ||||||
| 6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | GLY | A:489 | A:491 | 65.0 | 0.867 | T | -77.8 | 27.4 | 65.0 | 0.867 | 0.0 |
HOH |
9.002 |
O |
O |
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| GLY | B:489 | B:491 | 48.0 | 0.64 | S | 101.0 | 88.0 | 48.0 | 0.64 | 0.0 | |||||||||||||
| GLY | E:489 | E:491 | 62.0 | 0.827 | T | -100.2 | 26.3 | NA | NA | NA | |||||||||||||
| GLY | F:489 | F:491 | 43.0 | 0.573 | S | -67.2 | -66.5 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | GLY | A:484 | A:491 | 49.0 | 0.653 | T | -94.0 | -57.6 | 49.0 | 0.653 | 0.0 | ||||||
| GLY | D:484 | D:491 | 50.0 | 0.667 | T | -87.6 | -60.4 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | GLY | A:484 | A:491 | 62.0 | 0.827 | T | -100.2 | 9.2 | 62.0 | 0.827 | 0.0 | ||||||
| GLY | D:484 | D:491 | 62.0 | 0.827 | T | -99.8 | 16.3 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | GLY | A:486 | A:491 | 63.0 | 0.84 | G | -100.1 | 5.2 | 63.0 | 0.84 | 0.0 |
HOH |
6.506 |
N |
O |
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| GLY | D:486 | D:491 | 57.0 | 0.76 | G | -110.9 | 5.5 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | GLY | A:486 | A:491 | 61.0 | 0.813 | G | -106.5 | 1.6 | 61.0 | 0.813 | 0.0 |
HOH |
9.489 |
N |
O |
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| GLY | D:486 | D:491 | 57.0 | 0.76 | T | -114.0 | 10.3 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | GLY | A:484 | A:491 | 60.0 | 0.8 | G | -99.9 | -14.1 | 60.0 | 0.8 | 0.0 | ||||||
| GLY | D:484 | D:491 | 60.0 | 0.8 | S | -102.1 | -21.5 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | GLY | A:487 | A:491 | 65.0 | 0.867 | G | -110.6 | 2.4 | 65.0 | 0.867 | 0.0 | ||||||
| GLY | D:487 | D:491 | 59.0 | 0.787 | G | -108.2 | 7.1 | NA | NA | NA | |||||||||||||
| GLY | G:487 | G:491 | 57.0 | 0.76 | S | -126.5 | -9.6 | NA | NA | NA | |||||||||||||
| GLY | J:487 | J:491 | 62.0 | 0.827 | G | -108.9 | -5.7 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | GLY | A:482 | A:491 | 52.0 | 0.693 | S | -100.5 | -37.7 | 52.0 | 0.693 | 0.0 | ||||||
| GLY | B:482 | B:491 | 59.0 | 0.787 | G | -119.0 | 3.7 | NA | NA | NA | |||||||||||||
| 3c5w | 1 | P30153 | 88.39 | 1e-141 |
X-RAY |
2008-04-15 | GLY | A:134 | A:491 | 61.0 | 0.813 | G | -92.1 | -3.8 | 61.0 | 0.813 | 0.0 | ||||||
| 4lac | 2 | ? | 85.71 | 9e-137 |
X-RAY |
2013-10-09 | GLY | B:160 | A:491 | 67.0 | 0.893 | G | -105.9 | 10.4 | 67.0 | 0.893 | 0.0 |
HOH |
7.905 |
O |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | GLY | A:491 | A:491 | 61.0 | 0.813 | G | -97.4 | 3.2 | |
| af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | ASN | A:503 | A:503 | 96.0 | 0.6 | G | -105.9 | 8.3 | |