Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52724361 . G A CCDS12849.1:NM_014225.5:c.1493cGc>cAc_NP_055040.2:p.498R>H Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ARG A:498 A:498 17.0 0.076 H -66.5 -40.4 13.0 0.058 0.018 B:P67775:0.018
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ARG A:498 A:498 16.0 0.071 H -59.0 -42.5 12.0 0.053 0.018 B:P67775:0.018
 HOH
 7.423
 N
 O
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:498 A:498 23.0 0.102 H -62.1 -41.7 NA NA NA
ARG D:498 D:498 26.0 0.116 H -59.6 -35.0 19.0 0.084 0.032 F:P67775:0.031
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ARG A:498 A:498 15.0 0.067 H -61.4 -39.2 11.0 0.049 0.018 B:P67775:0.018
 SO4
HOH
 8.839
7.214
 NH2
N
 O3
O
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ARG A:498 A:498 15.0 0.067 H -63.9 -43.4 12.0 0.053 0.014 B:P67775:0.013
 SO4
HOH
 8.932
8.118
 NH2
NH2
 O3
O
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 ARG A:498 A:498 52.0 0.231 H -67.3 -41.3 45.0 0.2 0.031 C:P67775:0.031
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 ARG J:498 P:498 31.0 0.138 H -66.0 -41.2 27.0 0.12 0.018 K:P67775:0.018
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 ARG A:498 A:498 25.0 0.111 H -111.5 -45.1 16.0 0.071 0.04 C:P67775:0.04
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 ARG EA:498 p:498 22.0 0.098 H -67.4 -41.1 15.0 0.067 0.031 FA:P67775:0.031
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 ARG A:498 A:498 22.0 0.098 H -82.5 -10.4 14.0 0.062 0.036 C:P67775:0.036
ARG D:498 D:498 9.0 0.04 H -55.4 -43.4 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 ARG A:498 A:498 28.0 0.124 H -48.9 -47.4 28.0 0.124 0.0
ARG B:498 B:498 29.0 0.129 H -57.2 -37.0 NA NA NA
ARG C:498 C:498 23.0 0.102 H -56.2 -41.0 NA NA NA
ARG D:498 D:498 23.0 0.102 H -90.7 -20.2 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 ARG A:497 A:497 18.0 0.08 H -65.0 -32.6 18.0 0.08 0.0 HOH
 2.615
 NH1
 O
ARG B:497 B:497 33.0 0.147 H -61.3 -37.6 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 ARG A:497 A:498 27.0 0.12 H -60.8 -40.2 17.0 0.076 0.044 C:P67775:0.044
 HOH
 7.028
 N
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 ARG A:499 A:498 27.0 0.12 H -60.3 -46.8 27.0 0.12 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 ARG A:496 A:498 35.0 0.156 H -59.6 -36.2 35.0 0.156 0.0 HOH
 3.568
 NH2
 O
ARG B:496 B:498 44.0 0.196 H -62.4 -44.6 44.0 0.196 0.0
ARG E:496 E:498 22.0 0.098 H -63.8 -41.6 NA NA NA
ARG F:496 F:498 32.0 0.142 H -59.0 -39.3 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:491 A:498 20.0 0.089 H -46.7 -50.6 11.0 0.049 0.04 C:P67775:0.04
ARG D:491 D:498 16.0 0.071 H -52.7 -44.3 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:491 A:498 20.0 0.089 H -53.0 -39.8 12.0 0.053 0.036 C:P67775:0.036
ARG D:491 D:498 18.0 0.08 H -55.2 -34.4 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ARG A:493 A:498 21.0 0.093 H -68.1 -37.2 15.0 0.067 0.026 C:P67775:0.027
 HOH
 3.517
 NH2
 O
ARG D:493 D:498 22.0 0.098 H -62.8 -42.5 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ARG A:493 A:498 19.0 0.084 H -62.7 -40.0 13.0 0.058 0.026 C:P67775:0.027
 HOH
 4.930
 N
 O
ARG D:493 D:498 23.0 0.102 H -72.1 -42.8 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 ARG A:491 A:498 23.0 0.102 H -77.7 -54.4 16.0 0.071 0.031 C:P67775:0.031
ARG D:491 D:498 25.0 0.111 H -73.8 -65.8 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 ARG A:494 A:498 31.0 0.138 H -68.0 -41.6 18.0 0.08 0.058 C:P67775:0.058
ARG D:494 D:498 21.0 0.093 H -63.2 -45.1 NA NA NA
ARG G:494 G:498 25.0 0.111 H -66.9 -11.3 NA NA NA
ARG J:494 J:498 22.0 0.098 H -73.7 -29.9 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 ARG A:489 A:498 23.0 0.102 H -60.5 -33.1 23.0 0.102 0.0
ARG B:489 B:498 23.0 0.102 H -60.9 -38.9 NA NA NA
3c5w 1 P30153 88.39 1e-141 X-RAY
 2008-04-15 ARG A:141 A:498 22.0 0.098 H -50.6 -38.8 15.0 0.067 0.031 B:P67775:0.031
 HOH
 8.616
 C
 O
4lac 2 ? 85.71 9e-137 X-RAY
 2013-10-09 ARG B:167 A:498 21.0 0.093 H -64.6 -38.1 15.0 0.067 0.026 C:P67775:0.027
 HOH
 6.730
 NE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 ARG A:498 A:498 20.0 0.089 H -59.7 -42.5
af-p30154-f1 1 P30154 86.4 0.0 ARG A:510 A:510 30.0 0.133 H -58.4 -43.3