Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52725404 . C A CCDS12849.1:NM_014225.5:c.1571aCg>aAg_NP_055040.2:p.524T>K Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 THR A:524 A:524 5.0 0.036 H -54.0 -38.1 5.0 0.036 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 THR A:524 A:524 5.0 0.036 H -55.3 -36.5 5.0 0.036 0.0
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 THR A:524 A:524 18.0 0.129 H -49.9 -37.0 NA NA NA
THR D:524 D:524 18.0 0.129 H -52.9 -29.1 18.0 0.129 0.0
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 THR A:524 A:524 5.0 0.036 H -57.6 -35.0 5.0 0.036 0.0
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 THR A:524 A:524 6.0 0.043 H -61.2 -36.2 6.0 0.043 0.0
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 THR A:524 A:524 16.0 0.114 H -63.6 -45.1 16.0 0.114 0.0
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 THR J:524 P:524 11.0 0.079 H -65.2 -46.7 6.0 0.043 0.036 B:Q9H0H0:0.036
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 THR A:524 A:524 16.0 0.114 H -66.9 -38.4 16.0 0.114 0.0
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 THR EA:524 p:524 19.0 0.136 H -66.8 -42.4 19.0 0.136 0.0
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 THR A:524 A:524 20.0 0.143 H -95.7 -36.8 20.0 0.143 0.0
THR D:524 D:524 21.0 0.15 H -59.7 -51.7 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 THR A:524 A:524 8.0 0.057 H -78.7 -49.9 8.0 0.057 0.0
THR B:524 B:524 18.0 0.129 H -77.8 -40.4 NA NA NA
THR C:524 C:524 12.0 0.086 H -97.4 -37.4 NA NA NA
THR D:524 D:524 21.0 0.15 T -69.6 -47.4 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 THR A:523 A:523 13.0 0.093 H -64.6 -42.8 13.0 0.093 0.0 HOH
 2.717
 OG1
 O
THR B:523 B:523 28.0 0.2 H -60.7 -43.5 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 THR A:523 A:524 6.0 0.043 H -61.4 -42.4 6.0 0.043 0.0 HOH
 3.032
 OG1
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 THR A:525 A:524 18.0 0.129 H -74.1 -29.4 18.0 0.129 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 THR A:522 A:524 8.0 0.057 H -69.8 -41.5 8.0 0.057 0.0
THR B:522 B:524 42.0 0.3 H -86.2 -22.7 42.0 0.3 0.0
THR E:522 E:524 7.0 0.05 H -86.5 -22.6 NA NA NA
THR F:522 F:524 8.0 0.057 H -69.0 -45.6 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 THR A:517 A:524 16.0 0.114 H -53.9 -30.5 16.0 0.114 0.0
THR D:517 D:524 17.0 0.121 T -65.6 -7.1 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 THR A:517 A:524 16.0 0.114 H -80.7 -20.6 16.0 0.114 0.0
THR D:517 D:524 17.0 0.121 H -73.0 -11.6 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 THR A:519 A:524 17.0 0.121 H -65.1 -45.5 17.0 0.121 0.0 PEG
HOH
 5.547
2.609
 OG1
OG1
 C1
O
THR D:519 D:524 16.0 0.114 H -60.6 -40.7 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 THR A:519 A:524 13.0 0.093 H -64.0 -47.9 13.0 0.093 0.0 HOH
 2.586
 OG1
 O
THR D:519 D:524 18.0 0.129 H -51.5 -44.8 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 THR A:517 A:524 6.0 0.043 H -72.8 -56.0 6.0 0.043 0.0
THR D:517 D:524 5.0 0.036 H -61.4 -66.1 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 THR A:520 A:524 10.0 0.071 H -69.1 -40.4 10.0 0.071 0.0
THR D:520 D:524 17.0 0.121 H -73.3 -35.6 NA NA NA
THR G:520 G:524 18.0 0.129 H -59.0 -30.8 NA NA NA
THR J:520 J:524 5.0 0.036 H -84.7 -27.8 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 THR A:515 A:524 18.0 0.129 H -46.3 -30.9 18.0 0.129 0.0
THR B:515 B:524 16.0 0.114 H -48.6 -40.6 NA NA NA
3c5w 1 P30153 88.39 1e-141 X-RAY
 2008-04-15 THR A:167 A:524 15.0 0.107 H -62.6 -43.1 15.0 0.107 0.0 HOH
 2.724
 OG1
 O
4lac 2 ? 85.71 9e-137 X-RAY
 2013-10-09 THR B:193 A:524 24.0 0.171 H -63.1 -48.3 24.0 0.171 0.0 HOH
 6.723
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 THR A:524 A:524 12.0 0.086 H -73.8 -41.7
af-p30154-f1 1 P30154 86.4 0.0 ILE A:536 A:536 35.0 0.2 H -74.5 -42.3