Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 52725412 . C A CCDS12849.1:NM_014225.5:c.1579Cgc>Agc_NP_055040.2:p.527R>S Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ie3 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ARG A:527 A:527 149.0 0.662 H -65.6 -37.5 149.0 0.662 0.0
2ie4 1 Q96DH3 100.0 0.0 X-RAY
 2006-11-07 ARG A:527 A:527 148.0 0.658 H -65.2 -36.1 148.0 0.658 0.0
2npp 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:527 A:527 152.0 0.676 H -55.0 -41.0 NA NA NA
ARG D:527 D:527 153.0 0.68 H -56.4 -29.6 153.0 0.68 0.0
3k7v 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ARG A:527 A:527 151.0 0.671 H -68.6 -27.0 151.0 0.671 0.0
3k7w 1 P30153 100.0 0.0 X-RAY
 2009-11-03 ARG A:527 A:527 153.0 0.68 H -65.1 -40.2 153.0 0.68 0.0
6nts 1 P30153 100.0 0.0 EM
 2020-05-06 ARG A:527 A:527 160.0 0.711 H -81.8 -38.6 160.0 0.711 0.0
7cun 10 P30153 100.0 0.0 EM
 2020-11-25 ARG J:527 P:527 167.0 0.742 H -80.6 -18.5 124.0 0.551 0.191 B:Q9H0H0:0.191
7k36 1 P30153 100.0 0.0 EM
 2021-03-10 ARG A:527 A:527 140.0 0.622 H -70.0 -48.1 140.0 0.622 0.0
7pks 31 P30153 100.0 0.0 EM
 2021-12-08 ARG EA:527 p:527 149.0 0.662 H -67.6 -42.0 141.0 0.627 0.035 W:Q9H0H0:0.036
2iae 1 Q76MZ3 99.83 0.0 X-RAY
 2006-12-26 ARG A:527 A:527 198.0 0.88 H -111.0 -26.8 198.0 0.88 0.0
ARG D:527 D:527 195.0 0.867 H -65.8 -15.4 NA NA NA
2pf4 1 Q76MZ3 99.83 0.0 X-RAY
 2007-08-07 ARG A:527 A:527 147.0 0.653 H -68.6 -22.6 147.0 0.653 0.0
ARG B:527 B:527 152.0 0.676 H -52.5 -46.3 NA NA NA
ARG C:527 C:527 170.0 0.756 G -66.1 -35.1 NA NA NA
ARG D:527 D:527 142.0 0.631 T -66.0 -31.6 NA NA NA
1b3u 1 P30153 100.0 0.0 X-RAY
 1999-04-12 ARG A:526 A:526 143.0 0.636 H -67.1 -33.6 143.0 0.636 0.0 HOH
 2.522
 NH1
 O
ARG B:526 B:526 223.0 0.991 H -57.4 -41.0 NA NA NA
3fga 1 Q76MZ3 99.83 0.0 X-RAY
 2009-09-22 ARG A:526 A:527 170.0 0.756 H -68.4 -34.9 170.0 0.756 0.0 HOH
 4.114
 NH2
 O
6ef4 1 Q76MZ3 99.66 0.0 X-RAY
 2019-06-26 ARG A:528 A:527 152.0 0.676 H -60.0 -36.3 152.0 0.676 0.0
6iur 1 P30153 100.0 0.0 X-RAY
 2019-12-04 ARG A:525 A:527 186.0 0.827 H -60.8 -41.3 186.0 0.827 0.0
ARG B:525 B:527 72.0 NA H -65.1 -51.9 72.0 NA NA
ARG E:525 E:527 167.0 0.742 H -74.5 -32.0 NA NA NA
ARG F:525 F:527 184.0 0.818 H -62.0 -37.8 NA NA NA
2nyl 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:520 A:527 156.0 0.693 H -61.3 -12.7 156.0 0.693 0.0
ARG D:520 D:527 163.0 0.724 T -50.1 -16.4 NA NA NA
2nym 1 Q96DH3 100.0 0.0 X-RAY
 2006-12-12 ARG A:520 A:527 154.0 0.684 H -51.9 -23.8 154.0 0.684 0.0
ARG D:520 D:527 159.0 0.707 H -41.5 -30.5 NA NA NA
4i5l 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ARG A:522 A:527 151.0 0.671 H -63.4 -37.4 151.0 0.671 0.0 PEG
HOH
 8.643
2.423
 NE
NE
 C1
O
ARG D:522 D:527 143.0 0.636 H -59.5 -29.5 NA NA NA
4i5n 1 P30153 99.66 0.0 X-RAY
 2013-05-08 ARG A:522 A:527 158.0 0.702 H -69.5 -34.7 158.0 0.702 0.0 HOH
 7.005
 NH2
 O
ARG D:522 D:527 147.0 0.653 H -61.8 -31.2 NA NA NA
3dw8 1 P30153 100.0 0.0 X-RAY
 2008-10-07 ARG A:520 A:527 150.0 0.667 H -67.8 -31.4 150.0 0.667 0.0
ARG D:520 D:527 146.0 0.649 H -80.9 -23.9 NA NA NA
5w0w 1 P30153 100.0 0.0 X-RAY
 2018-01-17 ARG A:523 A:527 148.0 0.658 H -69.0 -34.7 148.0 0.658 0.0
ARG D:523 D:527 169.0 0.751 H -65.9 -26.0 NA NA NA
ARG G:523 G:527 160.0 0.711 T -71.8 -9.5 NA NA NA
ARG J:523 J:527 159.0 0.707 H -72.0 -19.4 NA NA NA
2pkg 1 P30153 100.0 0.0 X-RAY
 2007-05-15 ARG A:518 A:527 150.0 0.667 H -65.8 -47.4 150.0 0.667 0.0
ARG B:518 B:527 158.0 0.702 H -50.4 -35.6 NA NA NA
3c5w 1 P30153 88.39 1e-141 X-RAY
 2008-04-15 ARG A:170 A:527 145.0 0.644 H -72.7 -21.3 145.0 0.644 0.0 HOH
 6.659
 NH2
 O
4lac 2 ? 85.71 9e-137 X-RAY
 2013-10-09 ARG B:196 A:527 206.0 0.916 H -63.3 -40.1 206.0 0.916 0.0 HOH
 2.951
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30153-f1 1 P30153 100.0 0.0 ARG A:527 A:527 143.0 0.636 H -63.1 -37.5
af-p30154-f1 1 P30154 86.4 0.0 LYS A:539 A:539 123.0 0.615 H -58.8 -43.0