Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 52725418 | . | G | A | CCDS12849.1:NM_014225.5:c.1585Gct>Act_NP_055040.2:p.529A>T | Homo sapiens protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ie3 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | ALA | A:529 | A:529 | 3.0 | 0.026 | G | -63.4 | -17.4 | 3.0 | 0.026 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | ALA | A:529 | A:529 | 3.0 | 0.026 | G | -61.0 | -12.3 | 3.0 | 0.026 | 0.0 |
HOH |
9.707 |
O |
O |
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| 2npp | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ALA | A:529 | A:529 | 5.0 | 0.043 | G | -73.8 | -10.2 | NA | NA | NA | ||||||
| ALA | D:529 | D:529 | 6.0 | 0.052 | G | -79.5 | -2.6 | 6.0 | 0.052 | 0.0 | |||||||||||||
| 3k7v | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | ALA | A:529 | A:529 | 3.0 | 0.026 | G | -64.3 | -10.5 | 3.0 | 0.026 | 0.0 |
SO4 |
8.876 |
O |
O3 |
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| 3k7w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2009-11-03 | ALA | A:529 | A:529 | 2.0 | 0.017 | G | -59.1 | -11.9 | 2.0 | 0.017 | 0.0 |
SO4 |
8.901 |
O |
O3 |
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| 6nts | 1 | P30153 | 100.0 | 0.0 |
EM |
2020-05-06 | ALA | A:529 | A:529 | 10.0 | 0.087 | T | -63.6 | -23.1 | 10.0 | 0.087 | 0.0 | ||||||
| 7cun | 10 | P30153 | 100.0 | 0.0 |
EM |
2020-11-25 | ALA | J:529 | P:529 | 7.0 | 0.061 | T | -91.4 | -23.1 | 7.0 | 0.061 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 100.0 | 0.0 |
EM |
2021-03-10 | ALA | A:529 | A:529 | 10.0 | 0.087 | T | -56.0 | -7.7 | 10.0 | 0.087 | 0.0 | ||||||
| 7pks | 31 | P30153 | 100.0 | 0.0 |
EM |
2021-12-08 | ALA | EA:529 | p:529 | 7.0 | 0.061 | G | -79.7 | -7.1 | 7.0 | 0.061 | 0.0 | ||||||
| 2iae | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2006-12-26 | ALA | A:529 | A:529 | 6.0 | 0.052 | T | -71.6 | -3.8 | 6.0 | 0.052 | 0.0 | ||||||
| ALA | D:529 | D:529 | 18.0 | 0.157 | G | -67.0 | -4.7 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2007-08-07 | ALA | A:529 | A:529 | 5.0 | 0.043 | T | -66.3 | 11.3 | 5.0 | 0.043 | 0.0 | ||||||
| ALA | B:529 | B:529 | 2.0 | 0.017 | G | -58.2 | -22.7 | NA | NA | NA | |||||||||||||
| ALA | C:529 | C:529 | 5.0 | 0.043 | G | -54.4 | -22.6 | NA | NA | NA | |||||||||||||
| ALA | D:529 | D:529 | 59.0 | 0.513 | -141.3 | 128.0 | NA | NA | NA | ||||||||||||||
| 1b3u | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
1999-04-12 | ALA | A:528 | A:528 | 3.0 | 0.026 | G | -58.9 | -21.4 | 3.0 | 0.026 | 0.0 |
HOH |
2.700 |
O |
O |
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| ALA | B:528 | B:528 | 16.0 | 0.139 | T | -43.5 | -39.6 | NA | NA | NA | |||||||||||||
| 3fga | 1 | Q76MZ3 | 99.83 | 0.0 |
X-RAY |
2009-09-22 | ALA | A:528 | A:529 | 13.0 | 0.113 | T | -51.1 | -18.5 | 13.0 | 0.113 | 0.0 | ||||||
| 6ef4 | 1 | Q76MZ3 | 99.66 | 0.0 |
X-RAY |
2019-06-26 | ALA | A:530 | A:529 | 11.0 | 0.096 | G | -74.6 | -17.9 | 11.0 | 0.096 | 0.0 | ||||||
| 6iur | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2019-12-04 | ALA | A:527 | A:529 | 12.0 | 0.104 | T | -58.8 | -32.3 | 12.0 | 0.104 | 0.0 | ||||||
| ALA | B:527 | B:529 | 25.0 | 0.217 | H | -74.4 | -29.5 | 25.0 | 0.217 | 0.0 | |||||||||||||
| ALA | E:527 | E:529 | 5.0 | 0.043 | G | -63.6 | -32.7 | NA | NA | NA | |||||||||||||
| ALA | F:527 | F:529 | 9.0 | 0.078 | H | -61.2 | -33.1 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ALA | A:522 | A:529 | 8.0 | 0.07 | S | -59.3 | 8.6 | 8.0 | 0.07 | 0.0 | ||||||
| ALA | D:522 | D:529 | 5.0 | 0.043 | S | -49.6 | -1.5 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ALA | A:522 | A:529 | 5.0 | 0.043 | T | -53.4 | -4.1 | 5.0 | 0.043 | 0.0 | ||||||
| ALA | D:522 | D:529 | 3.0 | 0.026 | G | -48.8 | -9.3 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | ALA | A:524 | A:529 | 12.0 | 0.104 | T | -59.9 | -22.3 | 12.0 | 0.104 | 0.0 |
HOH |
4.362 |
CB |
O |
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| ALA | D:524 | D:529 | 10.0 | 0.087 | G | -65.8 | -15.1 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 99.66 | 0.0 |
X-RAY |
2013-05-08 | ALA | A:524 | A:529 | 16.0 | 0.139 | G | -69.3 | -13.1 | 16.0 | 0.139 | 0.0 |
HOH |
4.992 |
O |
O |
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| ALA | D:524 | D:529 | 16.0 | 0.139 | G | -71.1 | -9.3 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2008-10-07 | ALA | A:522 | A:529 | 13.0 | 0.113 | T | -60.2 | -8.8 | 13.0 | 0.113 | 0.0 | ||||||
| ALA | D:522 | D:529 | 4.0 | 0.035 | T | -62.4 | -7.9 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | ALA | A:525 | A:529 | 8.0 | 0.07 | G | -67.4 | -3.8 | 8.0 | 0.07 | 0.0 | ||||||
| ALA | D:525 | D:529 | 12.0 | 0.104 | T | -66.6 | -9.6 | NA | NA | NA | |||||||||||||
| ALA | G:525 | G:529 | 3.0 | 0.026 | T | -65.7 | -3.3 | NA | NA | NA | |||||||||||||
| ALA | J:525 | J:529 | 5.0 | 0.043 | G | -64.5 | -0.0 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 100.0 | 0.0 |
X-RAY |
2007-05-15 | ALA | A:520 | A:529 | 12.0 | 0.104 | T | -63.3 | 11.7 | 12.0 | 0.104 | 0.0 | ||||||
| ALA | B:520 | B:529 | 9.0 | 0.078 | G | -57.5 | -17.6 | NA | NA | NA | |||||||||||||
| 3c5w | 1 | P30153 | 88.39 | 1e-141 |
X-RAY |
2008-04-15 | ALA | A:172 | A:529 | 5.0 | 0.043 | G | -60.1 | -23.7 | 5.0 | 0.043 | 0.0 |
HOH |
5.207 |
O |
O |
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| 4lac | 2 | ? | 85.71 | 9e-137 |
X-RAY |
2013-10-09 | ALA | B:198 | A:529 | 8.0 | 0.07 | G | -61.2 | -17.4 | 8.0 | 0.07 | 0.0 |
HOH |
4.585 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30153-f1 | 1 | P30153 | 100.0 | 0.0 | ALA | A:529 | A:529 | 9.0 | 0.078 | T | -60.2 | -20.7 | |
| af-p30154-f1 | 1 | P30154 | 86.4 | 0.0 | ALA | A:541 | A:541 | 15.0 | 0.13 | T | -60.7 | -21.2 | |